Raw Plecanatide Acetate powder (467426-54-6) video
Plecanatide Description
Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation. It is an agonist of guanylate cyclase-C, it increases intestinal transit and fluid through a buildup of cGMP.
Plecanatide should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age.
Plecanatide Specifications
| Product Name | Plecanatide |
| Chemical Name | L-Leucine,L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-αglutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-Lcysteinyl-, cyclic (4→12),(7→15)-bis(disulfide);Plecanatide Impurtiy; SP-304; |
| Brand Name | Trulance |
| Drug Class | Peptide |
| CAS Number | 467426-54-6 |
| InChIKey | NSPHQWLKCGGCQR-DLJDZFDSSA-N |
| Molecular Formula | C65H104N18O26S4 |
| Molecular Weight | 1681.887 |
| Monoisotopic Mass | 1680.625 g/mol |
| Melting Point | N/A |
| Biological Half-Life | half-life (t½) cannot be calculated due to negligible systemic absorbance |
| Color | white to off-white |
| Solubility | Water Solubility:0.165 mg/mL |
| Storage Temperature | −20°C |
| Application | Used for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation. |
