July 20, 2023

Phcoker is a professional GMP manufacturer of PT-141 peptide that provide both form of PT-141 powder and PT-141 finished lyophilized powder in vial.  The regularly manufacturing specification include PT-141 5mg, PT-141 10mg, PT-141 15mg. Larger dosage and contract manufacturing service is available.

Monthly production capacity: >1,000,000 vials

Other Name:Vyleesi, PT141, Rekynda, bremelanotide acetate, Bremelanotide


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Raw Bremelanotide,α-MSH (PT-141) powder (189691-06-3) video


Molecular Formula:CsoHogN14O10
Molecular Weight:1025.182 g/mol
PubChem CID:9941379
CAS Number:189691-06-3
Synonyms:PT141, Rekynda, bremelanotide acetate, Bremelanotide


PT-141 also known as Bremelanotide, is a 7-amino acid peptide used to treat decreased libido in women who are not experiencing menopause and have not had low libido in the past and erectile dysfunction in men. It is sold under the brand name Vyleesi.

In the market of sex enhancement products, people are often familiar with Tadalafil(brand name is Cialis), Flibanserin(brand name addyi) etc. Today we are going to discuss with you another sex enhancing product name PT-141 or BremelanotideHow it is different from other sex enhancing products? Let’s take a look.

PT-141Bremelanotide Structure

PT-141 Bremelanotide Structure

What is PT-141Bremelanotide?

Peptide PT-141 (Bremelanotide) is a synthetic peptide developed from Melanotan 2. It is used to treat sexual dysfunction in both men and women. Unlike traditional drugs such as Tadalafil (Cialis), PT-141 acts on the brain and acts on the nervous system by activating neurons in the hypothalamus to increase libido. In 2019, Bremelanotide was approved by the FDA for the treatment of premenopausal women with hypoactive sexual desire disorder(HSDD). It is also useful in treating erectile dysfunction or impotence in men.

How Does PT-141(Bremelanotide) Works?

Bremelanotide PT-141 is a molecule that binds to and activates melanocortin receptors associated with skin pigmentation. Because of this, Bremelanotide PT-141 is currently administered via subcutaneous injection, which is best suited for areas with fatty deposits. The only legal form of the peptide is injectable, which is popular for its ability to quickly increase libido and sexual arousal in both men and women. It has been shown to increase physical arousal and genital circulation, thereby increasing male erections. PT-141 unlike common oral medications such as Viagra®, Cialis®, or Levitra®, PT-141 acts directly on the nervous system to stimulate sexual arousal. In addition, PT-141 may stimulate the release of dopamine, which is often considered a pleasure chemical. This hormone flows into the bloodstream of the reproductive organs, thereby increasing the physical pleasure of the sexual intercourse process. It also increases the sensitivity of nerve endings, which amplifies the look of messages sent from the brain to the body. Bremelanotide PT-141 is a novel treatment option for sexual dysfunction that is effective for both men and women.

What Are The Benefits Of PT-141(Bremelanotide)?

Numerous studies have surfaced that PT-141 can help treat a range of conditions, including erectile dysfunction in men, HSDD in premenopausal women, and even maintaining a happy mood. PT 141 works by stimulating the melanocortin receptor in the brain. It can be injected subcutaneously or inhaled through the nose to treat sexual dysfunction. It is known for its quick results, usually less than an hour. This peptide can provide many benefits to men and women with decreased libido and sexual performance. Here are the primary benefits of PT-141(Bremelanotide) for men and women:

1.PT-141 and Male Erectile Dysfunction

PT-141 has been studied as a potential treatment option for ED. Bremelanotide PT-141 is a melanocortin receptor agonist that works by stimulating the release of nitric oxide. This chemical helps relax the smooth muscles of the penis and increases blood flow. The increased blood flow helps improve erectile function in men with ED.

2.PT-141 and HSDD in Women

Studies have shown that about 10% of women in the United States have low or no sexual desire. Lack of libido in women, called Hypoactive Sexual Desire Disorder (HSDD), is associated with hormonal abnormalities as well as abnormal levels of dopamine and serotonin. Another potential benefit of PT-141 is its ability to increase sexual desire and arousal in women. It is particularly effective in premenopausal women with sexual arousal disorders.

3.PT-141 and Mood

As mentioned earlier, Bremelanotide PT-141 works on the nervous system to stimulate the release of dopamine, which acts as a pleasure-releasing chemical that improves the user’s overall mood and keeps them happy.

Bremelanotide PT-141 is one of the few solutions that has been clinically tested to determine its effectiveness in treating sexual dysfunction in both men and women. The results of the Phase II clinical trial were encouraging and may support the use of PT-141 as a solution for ED.

It is important to remember that the possible benefits of PT-141 are still being evaluated and more research is needed to determine how well it works and whether it is safe for long-term use. With that said, it is best to consult with your doctor before undergoing any treatment.

Individual seeking sex enhancement drugs like PT-141(Bremelanotide) to increase confident or improve happiness found that it is cost-efficient to buy PT-141 online. Some people who dare to try, even buy the PT-141 (Bremelanotide) powder to make different form such as PT-141 oral pill, PT-141 injection…Be careful if you want to buy PT-141(Bremelanotide) online, buy from the reliable manufacturers is important. Phcoker is good place to view.

What Are The Link Between PT-141 And Melanotan II?

PT-141, also known as Bremelanotide PT-141, is a synthetic peptide mixture derived from Melanotan II. Bremelanotide PT-141 was extracted from Melanotan 2 by a researcher who found that one of the side effects of Melanotan 2 was sexual arousal, and PT-141 peptide is known as a good alternative to improve sexual dysfunction.

PT-141(Bremelanotide) Side Effects And Safety

As with any medication like or treatment, there are potential side effects associated with PT-141 use. Common side effects of Pt-141 include flushing, headache, nausea, irritation, and redness at the injection site. While these side effects can be uncomfortable, their severity is usually considered mild to moderate. These symptoms usually go away on their own within a few hours of PT-141 use.

Less common side effect symptoms of PT-141 use: vomiting, blurred vision, dizziness, joint pain or swelling, runny or stuffy nose, etc. These symptoms are relatively rare and are experienced by only a small percentage of users. Although these symptoms are relatively rare, they are more serious in nature and it is important to seek medical attention as soon as possible if you experience them.

Compared to traditional medications such as Tadalafil(Cialis) that are associated with more serious side effects such as heart attack and stroke, the side effects of PT-141 are generally considered less serious. Many researchers do comparison between PT-141 and Tadalafil, Melanotan II to find out what are the differences and similarities.

How To Store PT-141(Bremelanotide)?

PT-141 lyophilized powder can be stored at room temperature for 30-60 days if you are using it for a short period of time. If you are not going to use the peptide lyophilized powder within 1-2 months, it should be stored at -18°C. Peptides can be stored for 1-2 years in this case. You can refer to the information from the peptide manufacturer where you buy the PT-141 powder.



Would you like to looking for high quality Bremelanotide PT-141 peptide manufacturer? Phcoker as one of professional peptide factory, all our peptides are pharmaceutical grade and produced accordance with GMP standard strictly.

As the best PT-141 peptide manufacturer, is not only supply the peptide PT-141(Bremelanotide) in powder form but provide the customized standard easy use vial form. You can buy the best price PT 141 and best quality peptide from this professional peptide manufacturer.


Where to buy

Vyleesi(PT-141) is available only with your doctor’s prescription.  If you are looking for a best online PT-141 peptide supplier, you have come a right place! Click and make a contact, you will get all the details. Before buy PT-141 (Bremelanotide), you may curious:

What Are The Advantages If Buy PT 141 From

  • 【Competitive Factory Price】

Factory direct sales, No middlemen make a difference.

  • 【Customization Service】

Product specifications can be customized to create your own peptide brand.

  • 【Quality Guarantee】

Professional lab reports along with shipment.

  • 【Fast Shipping】

Professional logistics customization solutions, on-time delivery.

  • 【Easy Payment】

Payment methods that are diverse.

  • 【365/24/7 Service】

High quality pre-sales and after-sales service, followed by product and order details consultation.

How To Get The Quick Price Of PT 141 Online?

  • Visit professional PT 141 supplier, choose the PT 141 you want to buy.
  • Leave your contact and message on Phcoker website, then submit to
  • The customer service will reply you in 12 hours once received your message, then talk in details about buy PT 141.

Does Support The Free Sample Of PT 141 Powder?

It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for sample.

Can I Appoint The PT 141 Colour When Buy PT 141?

YES! Phcoker as peptide manufacturer, provide colour customization of PT 141, easy to help you to build your PT 141 peptide brand.

Can I Appoint The Products Standard When Buy PT 141 From

YES! As one of the best PT 141 manufacturer, Phcoker not only provide the standard specification of PT 141 in 5mg, 10mg, but support standard customization. Provide the best support to build your own PT 141 brand.

Can I Buy PT 141 In Pure Powder Form From

YES! PT 141 powder is the base that use for PT 141 lyophilized powder manufacture. Phcoker provide PT 141 in both of pure powder form and semi-finished vial form.

Can I Buy Discount PT 141 Powder From

YES! Our factory produce high quality PT 141 powder in term and keep PT 141 powder in stock. You can buy high quality PT 141 powder in bulk. During promotion sale, you can buy PT 141 peptide by lower price. You can keep touch with our customer manager and they will update the latest bulk PT 141 price for you in time.



1. When should I use PT-141?

You should start subcutaneous injections at least 45 minutes before sexual activity. You can only do this two to three times a week, up to a maximum of eight injections a month. This is because you should not use more than the required dose every 24-36 hours.

2. Is PT-141 safe?

PT-141 is currently approved by the FDA as a natural and safe treatment for erectile dysfunction. In addition, because PT-141 works through the nervous system and not the cardiovascular system, it can be used in most adults and even in patients with heart complications.

3. Can PT-141 be used with Viagra?

Yes, PT-141 has been shown to be safe for use with Viagra (sildenafil). In clinical studies, the combination of the two increased erectile activity without causing any serious side effects.

4.Does PT-141 give you an erection?

Yes, it does. After injection PT-141, men find that they get erections as a natural result of increased sexual desire and attraction.

5. How often can you take PT-141?

As the effects of each 2mg dose last for up to 72 hours, it is recommended that the maximum dose is not exceeded during this time. Therefore, you should only take PT-141 3 times per week and no more than 8 times per month to safely benefit from the effects.

6. Does PT-141 really work?

PT-141 has been shown to be effective in helping men with sexual dysfunction thanks to its alternative method of subcutaneous injection. By acting on the nervous system and binding Melanotan receptors to the hypothalamus (the area of the brain responsible for sexual arousal), PT-141 is a quick-acting method that helps to increase libido and sexual drive. While Cialis and Viagra utilize the vascular system to increase blood flow just to promote an erection, PT-141 provides the brain with a natural stimulant to generate interest and attraction.


Referenced Citations

[1] Alabsi W, Eedara BB,  Encinas-Basurto D, Polt R, Mansour HM. Nose-to-Brain Delivery of Therapeutic Peptides as Nasal Aerosols. Pharmaceutics. 2022 Sep 5;14(9):1870. doi: 10.3390/pharmaceutics14091870. PMID: 36145618; PMCID: PMC9502087.

[2] Mayer D, Lynch SE. Bremelanotide: New Drug Approved for Treating Hypoactive Sexual Desire Disorder. Ann Pharmacother. 2020 Jul;54(7):684-690. doi: 10.1177/1060028019899152. Epub 2020 Jan 1. PMID: 31893927.

[3] Bartlik B, Sugarman A, Seenaraine S, Green S. FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire/Function in Women. On J Complement & Alt Med. 4(1): 2020. OJCAM. MS.ID.000578.

[4] Simon JA, Kingsberg SA, Portman D, Williams LA, Krop J, Jordan R, Lucas J, Clayton AH. Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder. Obstet Gynecol. 2019 Nov;134(5):909-917. doi: 10.1097/AOG.0000000000003514. PMID: 31599847; PMCID: PMC6819023.

[5] Wessells H, Fuciarelli K, Hansen J, Hadley ME, Hruby VJ, Dorr R, et al. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: Double-blind, placebo controlled crossover study. J Urol. 1998 Aug;160(2):389–93.

[6] King SH, Mayorov AV, Balse-Srinivasan P, Hruby VJ, Vanderah TW, Wessells H. Melanocortin receptors, melanotropic peptides and penile erection. Curr Top Med Chem. 2007;7(11):1098-1106. PMID: 17584130; PMCID: PMC2694735.

[7] Michelakis E, Tymchak W, Archer S. Sildenafil: from the bench to the bedside. CMAJ. 2000 Oct 31;163(9):1171-5. PMID: 11079066; PMCID: PMC80254.

[8] Safarinejad MR, Hosseini SY. Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo controlled study. J Urol. 2008 Mar;179(3):1066-71. doi: 10.1016/j.juro.2007.10.063. Epub 2008 Jan 18. PMID: 18206919.

[9] Sharot T, Guitart-Masip M, Korn CW, Chowdhury R, Dolan RJ. How dopamine enhances an optimism bias in humans. Curr Biol. 2012 Aug 21;22(16):1477-81. doi: 10.1016/j.cub.2012.05.053. Epub 2012 Jul 12. PMID: 22795698; PMCID: PMC3424419.

[10] Edinoff AN, Sanders NM, Lewis KB, Apgar TL, Cornett EM, Kaye AM, Kaye AD. Bremelanotide for Treatment of Female Hypoactive Sexual Desire. Neurol Int. 2022 Jan 4;14(1):75-88. doi: 10.3390/neurolint14010006. PMID: 35076581; PMCID: PMC8788464.

[11]Kim S, Cho MC, Cho SY, Chung H, Rajasekaran MR. Novel Emerging Therapies for Erectile Dysfunction. World J Mens Health. 2021 Jan;39(1):48-64. doi: 10.5534/wjmh.200007. Epub 2020 Mar 16. PMID: 32202086; PMCID: PMC7752520.

[12]Liu C, Kaeser PS. Mechanisms and regulation of dopamine release. Curr Opin Neurobiol. 2019 Aug;57:46-53. doi: 10.1016/j.conb.2019.01.001. Epub 2019 Feb 12. PMID: 30769276; PMCID: PMC6629510.


Author of this article:

Dr. Jean Zeng graduated from king’s college london Faculty of Life Sciences & Medicine.


Scientific Journal paper Author:


Palatin Technologies, Inc., Cranbury, New Jersey, USA


Palatin Technologies, Inc., Cranbury, New Jersey 08512, USA


Palatin Technologies, Inc., Cranbury, New Jersey, USA

Songlong Jiao

Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, School of Mechanical Engineering, SoutheastUniversity, Nanjing 211189, People’s Republic of China

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