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Gonadorelin Acetate (34973-08-5)

Gonadorelin acetate is a decapeptide that stimulates the synthesis and secretion of both pituitary………


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1677kg/month

Description

Gonadorelin Acetate (34973-08-5) video

 

Gonadorelin Acetate (34973-08-5) Description

Gonadorelin acetate is a decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.

Like naturally occurring gonadotropin-releasing hormone (GnRH), gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.

Gonadorelin Acetate (34973-08-5) Specifications

Product Name Gonadorelin Acetate
Chemical Name Luprolite acetate; Cystorelin; Fertiline; Lutrelef
Brand Name Factrel; Lutrepulse; Relisorm.
Drug Class Peptide
CAS Number 34973-08-5
InChIKey NGCGMRBZPXEPOZ-HBBGHHHDSA-N
Molecular Formula C55H75N17O13.C2H4O2
Molecular Weight 1242.36 g/mol
Monoisotopic Mass 1241.59
Melting Point   >158°C
Freezing Point −0.568°C
Biological Half-Life A few minutes (natural GnRH) up to 2 hours
Color white lyophilized powder
Solubility  Soluble in water, methanol.
Storage Temperature  2-8°c sealed preservation & transportation, avoidsunlight.
Application (1) Gonadotropin-releasing hormone;

(2) diagnostic aid (hypothalamic-pituitary-gonadal axis function);

(3) infertility therapy agent;

 


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