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Raw Gonadorelin Acetate powder (34973-08-5)

(1 customer review)

Raw Gonadorelin Acetate powder is a decapeptide that stimulates the synthesis and secretion of both pituitary………


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

Description

Raw Gonadorelin Acetate powder (34973-08-5) video

 

Raw Gonadorelin Acetate powder (34973-08-5) Description

Raw Gonadorelin Acetate powder is a decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.

Like naturally occurring gonadotropin-releasing hormone (GnRH), gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.

Raw Gonadorelin Acetate powder (34973-08-5) Specifications

Product Name Raw Gonadorelin Acetate powder
Chemical Name Luprolite acetate; Cystorelin; Fertiline; Lutrelef
Brand Name Factrel; Lutrepulse; Relisorm.
Drug Class Peptide
CAS Number 34973-08-5
InChIKey NGCGMRBZPXEPOZ-HBBGHHHDSA-N
Molecular Formula C55H75N17O13.C2H4O2
Molecular Weight 1242.36 g/mol
Monoisotopic Mass 1241.59
Melting Point   >158°C
Freezing Point −0.568°C
Biological Half-Life A few minutes (natural GnRH) up to 2 hours
Color white lyophilized powder
Solubility  Soluble in water, methanol.
Storage Temperature  2-8°c sealed preservation & transportation, avoidsunlight.
Application (1) Gonadotropin-releasing hormone;

(2) diagnostic aid (hypothalamic-pituitary-gonadal axis function);

(3) infertility therapy agent;

 


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References & product citations

2019 Most Comprehensive Introduction To Gonadorelin Acetate

 

References:

  1. Akın, O., Yavuz, S. T., Hacıhamdioğlu, B., Sarı, E., Gürsel, O., & Yeşilkaya, E. (2015). Anaphylaxis to gonadorelin acetate in a girl with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism, 28(11-12), 1387-1389.
  2. Rastogi, S., Shukla, S., Kalaivani, M., & Singh, G. N. (2018). Peptide-based therapeutics: Quality specifications, regulatory considerations, and prospects. Drug discovery today.
  3. Endo, N., Nagai, K., Tanaka, T., & Kamomae, H. (2013). Progesterone profiles in the caudal vena cava and jugular vein in response to pulsatile luteinizing hormone stimulation induced by GnRH treatment during the mid-luteal phase in lactating dairy cows. Journal of Reproduction and Development, 2012-191.

1 review for Raw Gonadorelin Acetate powder (34973-08-5)

  1. Phcoker

    Got Gonadorelin Acetate powder to test, test result show very high quality and purity!

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