Gonadorelin Acetate (34973-08-5) video
Gonadorelin Acetate (34973-08-5) Description
Gonadorelin acetate is a decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Like naturally occurring gonadotropin-releasing hormone (GnRH), gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.
Gonadorelin Acetate (34973-08-5) Specifications
|Product Name||Gonadorelin Acetate|
|Chemical Name||Luprolite acetate; Cystorelin; Fertiline; Lutrelef|
|Brand Name||Factrel; Lutrepulse; Relisorm.|
|Molecular Weight||1242.36 g/mol|
|Biological Half-Life||A few minutes (natural GnRH) up to 2 hours|
|Color||white lyophilized powder|
|Solubility||Soluble in water, methanol.|
|Storage Temperature||2-8°c sealed preservation & transportation, avoidsunlight.|
|Application||(1) Gonadotropin-releasing hormone;
(2) diagnostic aid (hypothalamic-pituitary-gonadal axis function);
(3) infertility therapy agent;