Desmopressin Acetate

July 20, 2023

Desmopressin is a man-made analogue of vasopressin which is the body’s natural anti-diuretic hormone released by the pituitary. It works by increasing water permeability in renal tubular cells, which decreases urine volume and increases urine concentration.
Desmopressin acetate (DDAVP, Stimate, Minirin) is a medication prescribed for the management of thirst and urination following head trauma or surgery involving the pituitary gland, and the treatment of diabetes insipidus.

Status:In Mass Production
Capacity: 1kg/month

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Raw Desmopressin Acetate powder (16679-58-6) video

Desmopressin Acetate Description

Octreotide is a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.

Desmopressin Acetate Specifications

Product NameDesmopressin Acetate
Chemical NameLeuprolide acetate,74381-53-6

, Leuprorelin acetate, Lupron, Enantone

Brand NameEligard
Drug ClassPeptide
CAS Number16679-58-6
Molecular FormulaC46H64N14O12S2
Molecular Weight1069.22
Monoisotopic Mass1069.3
Melting Point N/A
Biological Half-LifeFollowing an intranasal dose of 1.66 mcg of desmopressin, the median apparent terminal half-life was 2.8 hours. Terminal half-life significantly increased from 3 hours in normal healthy patients to 9 hours in patients with severe renal impairment. The oral terminal half life of desmopressin ranges from 2 to 3.11 hours.
ColorWhite or almost white, fluffy powder.
Solubility H2O: soluble20mg/mL, clear, colorless
Storage Temperature 0°C
ApplicationA medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels.

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