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MT2 (Melanotan-II) (121062-08-6)

Melanotan-II is a synthetic cyclic heptapeptide, an analog of alpha-melanotropin (4,10); capable of………


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1167kg/month

Description

MT2 (Melanotan-II) (121062-08-6) video

 

MT2 (Melanotan-II) (121062-08-6) Description

Melanotan-II is a synthetic cyclic heptapeptide, an analog of alpha-melanotropin (4,10); capable of stimulating melanin synthesis & promoting rapid tanning of skin; currently in trials for use in the prevention of sunlight-induced skin cancer.

MT2 (Melanotan-II) (121062-08-6) Specifications

Product Name MT2/Melanotan-II
Chemical Name Melanotan II; MelanotanII;

(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide

Brand Name N/A
Drug Class Peptide
CAS Number 121062-08-6
InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N
Molecular Formula C50H69N15O9
Molecular Weight 1024.198 g/mol
Monoisotopic Mass 1023.54 g/mol
Melting Point  >181°C (subl.)
Freezing Point ≥17.0
Biological Half-Life 33 hour
Color White
Solubility  Soluble in DMSO
Storage Temperature   –20 °C
Application Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.

Melanotan II Acetic Acid Salt, is a lab-made chemical that is similar to a hormone found in people. Melanotan II has been shown to have melanogenesis (tanning) and aphrodisiac effects on humans.

 


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References & product citations

The 6 Key Points on Melanotan-II/MT2 which you need to know

 

References

  1. Wessells, H., Levine, N., Hadley, M. E., Dorr, R., & Hruby, V. (2000). Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. International journal of impotence research12(S4), S74.
  2. Evans-Brown, M., Dawson, R. T., Chandler, M., & McVeigh, J. (2009). Use of melanotan I and II in the general population.
  3. Nelson, M. E., Bryant, S. M., & Aks, S. E. (2012). Melanotan II injection resulting in systemic toxicity and rhabdomyolysis. Clinical Toxicology50(10), 1169-1173.
  4. Heijboer, A. C., Van Den Hoek, A. M., Pijl, H., Voshol, P. J., Havekes, L. M., Romijn, J. A., & Corssmit, E. P. (2005). Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice. Diabetologia48(8), 1621-1626.
  5. Breindahl, T., Evans‐Brown, M., Hindersson, P., McVeigh, J., Bellis, M., Stensballe, A., & Kimergård, A. (2015). Identification and characterization by LC‐UV‐MS/MS of melanotan II skin‐tanning products sold illegally on the Internet. Drug testing and analysis7(2), 164-172.
  6. Li, G., Zhang, Y., Wilsey, J. T., & Scarpace, P. J. (2004). Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression. Journal of Endocrinology182(1), 123-132.

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