+86(1812)4514114 [email protected]

Raw Caffeic acid phenethyl ester powder (104594-70-9)

Raw Caffeic acid phenethyl ester powder is the phenethyl alcohol ester of caffeic acid and a bioactive……..


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1180kg/month

Description

Raw Caffeic acid phenethyl ester powder (104594-70-9) video

 

Raw Caffeic acid phenethyl ester powder (104594-70-9) Description

Raw Caffeic acid phenethyl ester powder is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and immunomodulating activities. Upon administration, Raw Caffeic acid phenethyl ester powder (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).

It has a role as an antineoplastic agent, an anti-inflammatory agent, an immunomodulator, a metabolite, an antioxidant, a neuroprotective agent, an antiviral agent and an antibacterial agent.

Raw Caffeic acid phenethyl ester powder (104594-70-9) Specifications

Product Name Raw Caffeic acid phenethyl ester powder
Chemical Name Raw Caffeic acid phenethyl ester powder;

Phenylethyl caffeate; Phenethyl caffeate; Caffeic acid 2-phenylethyl ester; β-Phenylethyl caffeate;

2-Phenylethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate

Brand Name No data for available
Drug Class Tyrosine Kinase Inhibitors, Inhibitors
CAS Number 104594-70-9
InChIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
Molecular Formula C17H16O4
Molecular Weight 284.311 g/mol
Monoisotopic Mass 284.31 g·mol−1
Melting Point  125-126ºC (dec.)
Boiling point 498.6±45.0 °C at 760 mmHg
Biological Half-Life No Data Available
Color off-white
Solubility  Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol.
Storage Temperature  Store at 0°C
Raw Caffeic acid phenethyl ester powder Application Cytotoxic agent against cancer cell lines. Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. It has also been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation.

 


=

Reviews

There are no reviews yet.

Be the first to review “Raw Caffeic acid phenethyl ester powder (104594-70-9)”

Your email address will not be published. Required fields are marked *

Shangke Chemical is a high-tech enterprise specializing in active pharmaceutical intermediates (APIs). To control the quality during production, a large number of experienced professionals, a first-class production equipment and laboratories are the key points.

Contact Us