Pyrroloquinoline quinone disodium salt (122628-50-6) video
Pyrroloquinoline quinone disodium salt (122628-50-6) Specifications
| Product Name | Pyrroloquinoline quinone disodium salt (122628-50-6) |
| Chemical Name | Pyrroloquinoline quinone sodium salt; disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat;PQQ, Pyrrolo-quinoline-quinone disodium salt;sodiuM 9-carboxy-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7-dicarboxylate;PQQ disodium |
| CAS Number | 122628-50-6 |
| InChIKey | UFVBOGYDCJNLPM-UHFFFAOYSA-L |
| SMILE | C1=C(C2=C(C(=O)C(=O)C3=C2NC(=C3)C(=O)O)N=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+] |
| Molecular Formula | C14H4N2Na2O8 |
| Molecular Weight | 374.17 |
| Monoisotopic Mass | 373.976304 g/mol |
| Melting Point | > 300℃ (decomposed during the assay) |
| Color | Reddish orange to Reddish Brown Fine Powder |
| Storage temp | 2-8°C |
| Solubility | Soluble in water |
| Application | Pyrroloquinoline quinone (PQQ) disodium salt is proposed for use due to its nutritive value in the United States (U.S.) in foods, such as energy, sport, and isotonic drinks; non-milk based meal replacement beverages; water (bottled, enhanced, fortified); milk-based meal replacement beverages; cereal and granola bars; and energy, meal replacement, and fortified bars. |
What is Pyrroloquinoline quinone disodium salt (PQQ disodium salt)?
PQQ is a new type of water-soluble vitamins, was first discovered as a cofactor for enzyme reactions in bacteria, in which it serves a similar function to that of B vitamins for humans. It is an oxidoreductase-based, exists in some micro-organisms, plants and animal tissues, not only involved in catalytic oxidation of the body reaction, but also has some special biological activity and physiological function. Trace of PQQ can improve the metabolism of biological tissue and growth function, very valuable.
How does Pyrroloquinoline quinone disodium salt work?
Pyrroloquinoline quinone disodium salt can involves a direct action on key enzymes involved in the energy producing compartments in our cells – the mitochondria, theapy improves energy production. Pyrroloquinoline quinone disodium salt In addition to having a powerful antioxidant effect, it also can protects against mitochondrial damage. Not only protects mitochondria from oxidative stress, it also promotes the spontaneous generation of new mitochondria within aging cells.
The benefits of Pyrroloquinoline quinone disodium salt
Pyrroloquinoline quinone disodium salt is a natural compound that already exists in our cells, it has good benefits in human:
– Help improve immune and higher brain function;
– Prevent and treat liver damage;
– Reduce free radical damage to human body;
– Regulate various neurological diseases;
– romote the absorption of amino acids;
– Prevent and treat alzheimer’s disease;
– Active NK cells, enhance the antitumor activity;
– Improved sleep quality and duration as well as other metrics secondary to improved sleep;
– Increased transcription factors that activate antioxidant pathways;
– Enhances the formation of new mitochondria and increases cellular energy production.
The application of Pyrroloquinoline quinone disodium salt
Pyrroloquinoline quinone disodium salt is the disodium salt of Pyrroloquinoline quinone, its function is same as Pyrroloquinoline quinone.
In a 2009 study published in the medical journal Food Style, Pyrroloquinoline Quinone has been shown to have the ability to help protect. It be used to protect cognitive decline (memory loss, learning difficulty, etc.) due to age, stroke or neurodegenerative disorders, and protection from cardiac and neurological ischemic events. Similar results were reported in a 2011 follow-up study in which Pyrroloquinoline Quinone was also given directly as a dietary supplement, such as milk-based meal replacement beverages.
Reference:
[1]Nakano M, Takahashi H, Koura S, Chung C, Tafazoli S, Roberts A. Acute and subchronic toxicity studies of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™) in rats. Regul Toxicol Pharmacol. 2014 Oct;70(1):107-21. doi: 10.1016/j.yrtph.2014.06.024. Epub 2014 Jul 1. PMID: 24995591.
[2]Itoh Y, Hine K, Miura H, Uetake T, Nakano M, Takemura N, Sakatani K. Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions. Adv Exp Med Biol. 2016;876:319-325. doi: 10.1007/978-1-4939-3023-4_40. PMID: 26782228.
[3]Nakano M, Kawasaki Y, Suzuki N, Takara T. Effects of Pyrroloquinoline Quinone Disodium Salt Intake on the Serum Cholesterol Levels of Healthy Japanese Adults. J Nutr Sci Vitaminol (Tokyo). 2015;61(3):233-40. doi: 10.3177/jnsv.61.233. PMID: 26226960.
[4]Rucker R, Chowanadisai W, Nakano M. Potential physiological importance of pyrroloquinoline quinone. Altern Med Rev. (2009)
[5]Noji N, et al. Simple and sensitive method for pyrroloquinoline quinone (PQQ) analysis in various foods using liquid chromatography/electrospray-ionization tandem mass spectrometry. J Agric Food Chem. (2007)
