AOD9604

July 19, 2023

Phcoker is a professional AOD 9604 GMP manufacturer that provide both form of AOD 9604 powder and AOD 9604 finished lyophilized powder in vial.  The regularly manufacturing specification include AOD 9604 5mg, AOD 9604 10mg. Larger dosage and contract manufacturing service is available.

Monthly production capacity: >1,000,000 vials


Other Name:221231-10-3,UNII-7UP768IP4M,7UP768IP4M,EX-A4625

 

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Raw AOD 9604 powder (221231-10-3) video

Properties


Sequence: H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-Ser-Cys(1)-Gly-Phe-OH
Molecular Formula: C78H123N23O23S2
Molecular Weight: 1815.1 g/mol
PubChem CID: 71300630
CAS Number: 221231-10-3
Synonyms: 221231-10-3,UNII-7UP768IP4M,7UP768IP4M,EX-A4625

Description


AOD 9604 Peptide is a synthetic alternative to growth hormone used to control fat burning. As a growth hormone lipolytic peptide fragment, it can enhance the body’s metabolism and accelerate the fat burning process. AOD 9604 was first discovered at Monash University in Australia with the aim of developing an anti-obesity drug. The discovery and production of the peptide AOD 9604 has dramatically improved the results of dietary restriction and exercise. Here are all the things you need to know about AOD9604 peptides and how it will benefit your body weight control.

The Structure Of AOD 9604

Structure AOD 9604

What Is AOD 9604 Peptide

Obesity is a serious problem that affects countless people around the world. Research shows that 25-50% of people in the United States are considered overweight or obese.[1][5] Although countless diet plans, exercise regimens, and weight-loss drugs have been introduced over the past decade or so to treat this problem, none have achieved the desired results.

Originally developed as an anti-obesity drug, AOD 9604 is composed of the C-terminal fragment of human growth hormone from amino acids 177-191 and an additional tyrosine residue at the N-terminus of the peptide. As an orally available lipopeptide fragment of human growth hormone, it retains its lipolytic properties but does not stimulate the production of IGF-1.

AOD 9604 is also known as “Anti Obesity Drug 9604”. In early studies, AOD9604 showed positive effects in breaking down fat. It is designed to target stubborn areas of fat and promote fat burning. And the side effects shown are lower than HGH(Human Growth Hormone).

Many people suffering from obesity and research experts in the field of weight loss have turned their attention to AOD 9604 peptide. They buy AOD9604 for further research, including its benefits for weight loss, use, etc., hoping to make more breakthroughs in the field of weight loss. It is difficult to find a reliable AOD 9604 peptide manufacturers online.

The Mechanism of Action Of AOD 9604

AOD 9604 was originally developed for use as an anti-obesity drug. As a polypeptide fragment of human GH, studies have shown that the main working principle of the AOD 9604 peptide is to imitate the way natural growth hormone regulates fat metabolism.[2][8]

AOD 9604 powder mainly targets fat cells and can detect fat cells in the body. It binds to receptors on these fat cells, initiating a signaling cascade within the cells. In addition, it can trigger a program in fat cells called apoptosis, which can destroy and break down fat cells, leading to a reduction in body fat mass and weight loss.

AOD 9604 peptide can also indirectly promote the body’s metabolism (improving insulin sensitivity, promoting glucose metabolism, etc.). This indirect effect can also promote weight loss and improve metabolic capabilities.

Researchers research AOD 9604 current findings indicate that AOD 9604 shows great promise as a weight loss and metabolic improvement treatment. Considering the research cost of AOD9604, researchers seeking AOD 9604 for weight loss research use, prefer to buy it online due to the easy purchase process and fast door to door shipping service.

The Benefits of AOD 9604 Powder

AOD 9604 powder is the active ingredient of AOD-9604 based pharmaceutical weight loss products. AOD 9064 peptide has received widespread attention as a weight loss peptide. [4][10]AOD 9604 powder provided by peptide supplier Phcoker has very important benefits in promoting fat loss and weight management:

Promote weight loss and fat loss

AOD 9604 can stimulate the breakdown of fat and inhibit the formation of new fat cells, thereby promoting fat loss. This gives AOD 9604 peptide its fat-reducing effect.[9][11]

Manage weight

Due to its ability to specifically target fat cells and promote fat metabolism, AOD 9604 is considered to be one of the good choices for weight management and metabolism promotion.

Preserve muscle mass

AOD 9604 can reduce fat, but unlike other weight loss drugs, AOD 9604 can reduce fat without losing muscle. It can help retain muscle mass.

Enhance athletic performance

Studies have shown that AOD 9604 can promote fat loss while improving muscle mass and endurance, thereby enhancing the user’s sports performance.

Promote the body’s metabolism

Through the metabolism of fat, AOD 9604 will have an impact on the levels of insulin and blood lipids, thereby improving the body’s metabolic health. This is good news for patients with diabetes and cardiovascular disease.

Improve bone health

In some clinical studies, AOD 9604 has shown the potential to repair bones and cartilage, enhance bone health, and prevent diseases such as osteoporosis.

Potential anti-aging effects

Some studies have shown that AOD 9604 peptide has potential anti-aging effects due to its metabolism and tissue repair effects.

Little side effects

Compared with other weight loss methods, AOD 9604 has fewer side effects. This is due to its more targeted effect on fat cells, resulting in less systemic effects.

Through the review of best AOD 9604 peptide benefits list, people have a deeper understanding of peptide AOD9604. It is easy to buy AOD9604 from pharmacies, medical research institutions, and peptide manufacturers. Be careful when purchasing AOD9604 online or off-line. AOD 9604 as an injectable peptide, it must be produced under strict GMP conditions and fully comply with pharmaceutical grade. Although it is very easy to purchase AOD9604 online, strict review of suppliers is required to ensure that the quality of the purchased products is guaranteed. Find out the best AOD9604 peptide manufacturer is a challenge.

AOD 9604 Vs Semaglutide: Differences,Similarities

When it comes to weight loss products, Semaglutide has to be mentioned. Semaglutide is approved by the FAD for different uses under different brand names, including Ozempic, Wegovy, and Rybelsus.

The U.S. Food & Drug Administration has recently granted Human GRAS status to AOD 9604, a substance included in the Generally Recognized As Safe (GRAS) program. This classification assures that when used according to its intended purpose, as outlined in the Federal Food, Drug, and Cosmetic Act, AOD 9604 is deemed safe for consumption as a food additive.

AOD 9604 injections are notably safe, with no documented health risks associated. This makes them a preferable option over conventional hormone-based weight loss treatments.

As Semaglutide and AOD 9604 are very popular weight loss peptides in the weight loss market, what are the differences and similarities between them? Let’s take a look.

AOD 9604 Vs Semaglutide

In order to have a deeper understanding the differences and similarities between Semaglutide and AOD 9604 petpide, researchers buy them from some famous peptide manufacturers like Phcoker to do comparison testing. If you are interested in weight loss peptides research, contact phcoker for more information is a good choice.

What are the Differences Between AOD 9604 peptide and Frag 176-191?

Both AOD 9604 peptide and Frag 176-191 have weight loss effects. AOD 9604 is a modified form of the C-terminus of HGH. It contains amino acids 177-191 of the HGH sequence. Frag 176-191 is a peptide fragment of HGH, which is generally considered to be related to the fat-reducing effect of HGH.

AOD 9604 peptide consists of HGH residues 176–191, with a tyrosine in place of the phenylalanine at the C-terminal end.

Frag 176-191 is a simpler fragment than AOD 9604. It is mainly used to promote weight loss, can stimulate lipolysis, and can inhibit fat production. By mimicking the fat-burning activity of natural HGH without the growth-promoting effects.

AOD 9604 5mg powder is commonly used to treat obesity and helps promote weight loss without adversely affecting blood sugar levels or growing tissue.

Frag 176-191 is a peptide fragment of HGH. Its mechanism of action is similar to AOD 9604. It can increase lipolysis and inhibit lipogenesis to promote fat loss. Studies have shown that Frag 176-191 can effectively reduce abdominal fat without affecting blood sugar levels.

Frag 176-191 is different from other products in that it has the function of reducing fat mass without increasing muscle mass. Its main purpose is for weight loss and fat reduction.

Both products can be used to promote weight loss, but more research is needed to show their similarities and differences. If you are interested in this aspect, make sure to purchase from a reliable supplier. There are many online manufacturers selling AOD 9604 peptide and Frag 176-191. Phcoker.com is a professional manufacturer and we can provide you with the best products at the best price.

What Are The Clinical Trials On AOD 9604?

The clinical research of AOD 9604 mainly focuses on fat reduction.[3][12] The following are some key points about the clinical research of AOD 9604 peptide:

  1. The weight loss effect of AOD 9604: Early clinical studies were mainly focused on the effect of AOD 9604 on fat loss and body metabolism. A 2004 study showed that subjects who took AOD 9604 experienced a decrease in body fat.
  2. Metabolic effects of AOD 9604: A study published in 2010 investigated the effect of AOD 9604 on glucose metabolism. This study showed that AOD 9604 powder can improve insulin sensitivity and glucose tolerance, which is important for the body. Metabolic health plays a very important role.
  3. Safety of AOD 9604: A study published in the “Journal of Clinical Endocrinology and Metabolism” in 2007 showed that AOD 9604 was safe and well-tolerated, and did not show significant good results in the study.
  4. Future research methods of AOD 9604: Although existing clinical studies have achieved objective prospects for the benefits of AOD 9604, more long-term experimental studies are needed to evaluate and analyze the various benefits and risks of this peptide. .

Compare to AOD 9604 finished vial form, the AOD 9604 raw powder form is the common use form for research use. Researchers can use AOD9604 powder to make into different forms like injection according to the research purpose. In another hand, AOD 9604 powder is relatively easier to buy, as it do not require the prescription and easy to buy online. The important is to buy from good peptide AOD 9604 manufacturers.

The Side Effects Of AOD 9604 Peptide

AOD 9604 is a peptide fragment derived from the GH molecule.[6][7][13] Although many studies have shown that this peptide is safe, you should also be aware of the possible side effects before using this drug:

  • Headache
  • Nausea
  • Redness and swelling at the injection site, etc.
  • Dizziness
  • Insomnia
  • Cough
  • Nasopharyngitis
  • Palpitations

AOD 9604, like any other drug, can cause side effects when mixed with other medications. You should seek the advice of your health care provider when treating with AOD 9604. Buy high quality AOD 9604 peptide is more guaranteed.

AOD 9604 For SaleAOD 9604 Peptide Supplier

AOD 9604 is an orally active lipolytic peptide fragment of human growth hormone that is generally believed to promote weight loss by enhancing fat metabolism.

Due to the benefits shown by AOD 9604 peptide, more and more researchers are studying this peptide to explore more potential benefits of AOD 9604. Currently you can see many peptide manufacturers selling AOD 9604 online. But when buying AOD 9604 powder, you need to find a reliable and trustworthy manufacturer.

Phcoker is a professional peptide manufacturer that can provide high-quality AOD 9604 raw powder and vials.Whether you are buying AOD 9604 in small quantities or in bulk, Phcoker will provide you with preferential prices. If you want to buy AOD 9604 online, Phcoker.com may be a good choice for you.

 

Manufacturers/Factory


AOD 9604 is a drug that can stimulate lipolysis and inhibit lipogenesis, and this drug has been approved by the FDA. AOD 9604 fat-burning peptide was originally developed as an anti-obesity drug. As a modified version of HGH, it can stimulate the body’s pituitary gland after injection, which will accelerate the body’s metabolism and increase weight loss. Some human studies have shown that although AOD 9604 has fat-breaking properties, it does not stimulate the production of IGF-1 at the same time. If you are troubled by stubborn fat, AOD 9604 weight loss peptide may be able to solve your problem.

As the best AOD 9604 peptide manufacturer, Phcoker is not only supply the peptide AOD 9604 in powder form but provide the customized standard easy use vial form.

You can buy the best price AOD 9604 and best quality peptide from this professional peptide manufacturer.

 

Where to buy


Would you like to buy the best AOD 9604 peptide from the best AOD 9604 suppliers in the market? You have come at the right place!

Phcoker.com as a peptide factory, is the best place where you can buy AOD 9604 in compeptitive price, from small to bulk quantity. Click and make a contact, you will get all the details. Before buy AOD 9604, you may curious:

What Are The Advantages If Buy AOD 9604 From Phcoker.com?

  • 【Competitive Factory Price】

Factory direct sales, No middlemen make a difference.

  • 【Customization Service】

Product specifications can be customized to create your own peptide brand.

  • 【Quality Guarantee】

Professional lab reports along with shipment.

  • 【Fast Shipping】

Professional logistics customization solutions, on-time delivery.

  • 【Easy Payment】

Payment methods that are diverse.

  • 【365/24/7 Service】

High quality pre-sales and after-sales service, followed by product and order details consultation.

How To Get The Quick Price Of AOD 9604 Online?

  • Visit professional AOD 9604 supplier Phcoker.com, choose the AOD 9604 you want to buy.
  • Leave your contact and message on Phcokerwebsite, then submit to Phcoker.com.
  • The customer service will reply you in 12 hours once received your message, then talk in details about buy AOD 9604.

Does Phcoker.com Support The Free Sample Of AOD 9604 Powder?

It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for sample.

Can I Appoint The AOD 9604 Colour When Buy AOD 9604?

YES! Phcoker as peptide manufacturer, provide colour customization of AOD 9604, easy to help you to build your AOD 9604 peptide brand.

Can I Appoint The Products Standard When Buy AOD 9604 From Phcoker.com?

YES! As one of the best AOD 9604 manufacturer, Phcoker not only provide the standard specification of AOD 9604 in 5mg, 10mg, but support standard customization. Provide the best support to build your own AOD 9604 brand.

Can I Buy AOD 9604 In Pure Powder Form From Phcoker.com?

YES! AOD 9604 powder is the base that use for AOD 9604 lyophilized powder manufacture. Phcoker provide AOD 9604 in both of pure powder form and semi-finished vial form.

Can I Buy Discount AOD 9604 Powder From Phcoker.com?

YES! Our factory produce high quality AOD 9604 powder in term and keep AOD 9604 powder in stock. You can buy high quality AOD 9604 powder in bulk. During promotion sale, you can buy AOD 9604 peptide by lower price. You can keep touch with our customer manager and they will update the latest bulk AOD 9604 price for you in time.

 

FAQ


What is AOD 9604?

AOD 9604 is a fat-burning weight-loss peptide that stimulates lipolysis and inhibits the formation of new fat cells.

Does AOD 9604 really work?

According to the research results of clinical trials, AOD 9604 has a very significant effect in promoting fat burning and improving the body’s metabolism.

Does AOD 9604 have other nicknames?

AOD 9604 is also known as lipotropin and Tyr-hGH fragment.

When is the best time to take AOD 9604?

If you want to get the best results from AOD 9604, you should preferably use it on an empty stomach. The best time to use it is in the morning, but you can also use it 30-45 minutes after the last meal.

In what environment should AOD 9604 be stored?

AOD 9604 should be kept in the refrigerator at a temperature between 25-46℉. Remember not to freeze it.

Is AOD 9604 safe?

Numerous studies have successfully shown that use of AOD 9604 is safe and that AOD 9604 is well tolerated.

How long will it take for me to see the effects of AOD 9604?

Since everyone’s physical condition is different, the time it takes to see the results of AOD 9604 is also different. But generally speaking, it usually takes at least 12 weeks to see the significant effects of AOD 9604 on your body.

How to inject AOD 9604 correctly?

The following is the correct way to inject AOD 9604:

  • Use a syringe to draw the required AOD 9604 solution
  • It is best to give subcutaneous injections in areas of the abdomen with a higher concentration of fat
  • Make sure the entire process is clean to avoid infection

Will AOD 9604 increase your appetite?

No, AOD 9604 will not only not increase your appetite, but it will help users increase their satiety and reduce food intake, thus promoting weight loss.

Is AOD 9604 nasal spray effective?

The common way of administration of AOD 9604 is subcutaneous injection, and the effectiveness of its nasal spray form requires more experiments. If you would like to use this form of AOD 9604, talk to your health care professional.

Referenced Citations


[1]Heffernan, M.; Summers, R. J.; Thorburn, A.; Ogru, E.; Gianello, R.; Jiang, W. J.; Ng, F. M.(December 2001). The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 142(12): 5182–5189. doi:10.1210/endo.142.12.8522. ISSN 0013-7227. PMID11713213.

[2]Stier, Heike; Vos, Evert; Kenley, David (2013-04-23). Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans. Journal of Endocrinology and Metabolism.3 (1–2): 7–15. doi:10.4021/jem157w. ISSN 1923-287X.

[3]Valentino, Michael A.; Lin, Jieru E.; Waldman, Scott A. (June 2010). Central and Peripheral Molecular Targets for Anti-Obesity Pharmacotherapy. Clinical Pharmacology and Therapeutics. 87 (6): 652–662. doi:10.1038/clpt.2010.57. ISSN 0009-9236. PMC 3136748. PMID20445536.

[4]Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM.The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice.Endocrinology. 2001 Dec;142(12):5182-9. doi: 10.1210/endo.142.12.8522.PMID:11713213.

[5]Heffernan MA, Thorburn AW, Fam B, Summers R, Conway-Campbell B, Waters MJ, Ng FM.Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment.Int J Obes Relat Metab Disord. 2001 Oct;25(10):1442-9. doi: 10.1038/sj.ijo.0801740..PMID:11673763

[6]Heffernan MA, Jiang WJ, Thorburn AW, Ng FM.Effects of oral administration of a synthetic fragment of human growth hormone on lipid metabolism.Am J Physiol Endocrinol Metab. 2000 Sep;279(3):E501 7. doi: 10.1152 ajpendo.2000.279.3.E501.PMID:10950816.

[7]Ng FM, Jiang WJ, Gianello R, Pitt S, Roupas P.Molecular and cellular actions of a structural domain of human growth hormone (AOD9401) on lipid metabolism in Zucker fatty rats.J Mol Endocrinol. 2000 Dec;25(3):287-98. doi: 10.1677/jme.0.0250287.PMID:11116208.

[8]Langin D.Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome.Pharmacol Res. 2006 Jun;53(6):482 91. doi:10.1016 j.phrs.2006.03.009. Epub 2006 Mar 27.PMID:16644234.

[9]Iughetti L, China M, Berri R, Predieri B.Pharmacological treatment of obesity in children and adolescents: present and future.J Obes. 2011;2011:928165. doi:10.1155 2011 928165. Epub 2010 Dec 15.PMID: 21197151.

[10]Misra M.Obesity pharmacotherapy: current perspectives and future directions.Curr Cardiol Rev. 2013 Feb 1;9(1):33 54. doi:10.2174 157340313805076322.PMID:23092275.

[11]Isidro ML, Cordido F.Approved and Off Label Uses of Obesity Medications, and Potential New Pharmacologic Treatment Options.Pharmaceuticals (Basel). 2010 Jan 12;3(1):125 145. doi: 10.3390 ph3010125.PMID:27713245.

[12]Habibullah MM, Mohan S, Syed NK, Makeen HA, Jamal QMS, Alothaid H, Bantun F, Alhazmi A, Hakamy A, Kaabi YA, Samlan G, Lohani M, Thangavel N, Al Kasim MA.Human Growth Hormone Fragment 176 191 Peptide Enhances the Toxicity of Doxorubicin Loaded Chitosan Nanoparticles Against MCF 7 Breast Cancer Cells.Drug Des Devel Ther. 2022 Jun 27;16:1963 1974. doi: 10.2147/DDDT.S367586. eCollection 2022.PMID: 35783198.

[13]Harpur CM, West AC, Le Page MA, Lam M, Hodges C, Oseghale O, Gearing AJ, Tate MD.Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection.Clin Transl Immunology. 2023 Mar 23;12(3):e1443. doi: 10.1002/cti2.1443. eCollection 2023.PMID: 36969366.

 

Author of this article:


Dr. Jean Zeng graduated from king’s college london Faculty of Life Sciences & Medicine.

 

Scientific Journal paper Author:


1.Mario Thevis

Center for Preventive Doping Research – Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany

2.Jing Jing

Shanghai Anti-doping Laboratory, Shanghai University of Sport, Shanghai, China

3.Steven Janvier

Division of Food, Medicines and Consumer Safety, Section Medicines and Healthcare Products, Scientific Institute of Public Health (WIV-ISP), J. Wytsmansstraat 14, B-1050 Brussels, Belgium

4.Gilles Coppieters

Doping Control Laboratory (DoCoLab), Ghent University, Department Diagnostic Sciences, Ottergemsesteenweg 460, B-9000 Ghent, Belgium

5.Sharon C. Cheetham

RenaSci Consultancy Ltd, BioCity, Nottingham, UK, NG1 1GF


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