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Raw AOD 9604 powder (221231-10-3)

AOD 9604 powder is a modified form Growth Hormone which is a 191 amino acid peptide. The last 15 amino acids (176-191)…..


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

 

Description

Raw AOD 9604 powder (221231-10-3) video

 

Raw AOD 9604 powder (221231-10-3) Description

Raw AOD 9604 powder (221231-10-3) is a potential anti-obesity peptide based on human growth hormone.

AOD 9604 powder is a modified form Growth Hormone which is a 191 amino acid peptide. The last 15 amino acids (176-191) of the Growth Hormone polypeptide have been reproduced as a specific peptide and is called GH Frag 176-191 or AOD 9604.

It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, Raw AOD 9604 powder stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans. Recent findings have shown, in addition to its fat loss properties, AOD 9604 processes many other regenerative properties associated with growth hormone. Currently trials are underway to show the application of AOD 9604 in osteoarthritis, hypercholesterolemia, bone and cartilage repair. Raw AOD 9604 powder (221231-10-3) has an excellent safety profile, recently obtaining Human GRAS status in the USA.

Raw AOD 9604 powder, also known as Tyr-hGH Frag 176-191 has been proven to have a strong fat burning capacity, without creating a desire to overeat. It doesn’t affect blood sugar or tissue growth. AOD-9604 activates degradation and fat burning (oxidation), by a method that doesn’t use hGH receptor. It has its own mechanism of action independent of hGH. Laboratory studies on rodents, pigs, dogs & humans have identified AOD-9604 mechanism where it triggers fat release from the obese fat cells predominantly and works to reduce the accumulation of new fat in fat cells as well as increasing fat burning. What is extraordinary about the AOD-9604 is its ability to reduce abdominal fat stores

 

Raw AOD 9604 powder (221231-10-3) Specifications

Product Name AOD 9604 powder
Chemical Name UNII-7UP768IP4M;7UP768IP4M
L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide.
Sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Brand Name N/A
Drug Class anti-obesity peptide
CAS Number 221231-10-3
InChIKey GVIYUKXRXPXMQM-BPXGDYAESA-N
Molecular Formula C78H123N23O23S2
Molecular Weight 1815.1 g/mol
Monoisotopic Mass 1813.86 g/mol
Melting Point  191.0~193.0ºC
Freezing Point N/A
Biological Half-Life N/A
Color White crystalline powder ; Lyophilized Powder
Solubility  Soluble in water or 1% acetic acid
Storage Temperature  Closed, below 2 ~ 8 C preservation
Application Obesity treatment

This peptide has an amino acid sequence that mimics the lipolytic region of human growth hormone (the region of this hormone thought to be responsible for burning fat) and it has been promoted variously as a weight loss supplement, as an aid to muscle and cartilage repair, and a treatment for osteoarthritis by its manufacturers. It is also known as lipotropin and Tyr-hGH fragment, and is generally available these days as a transdermal cream or an injectable.

 


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References & product citations

Peptide AOD 9604 Truth: What It Bring After Use AOD 9604?

 

References

  1. Stier, H., Vos, E., and Kenley, D. (2013). Safety and Tolerability of the Hexadecapeptide AOD-9604 in Humans. Journal of Endocrinology and Metabolism.
  2. Ng, F.M., Sharma, L., Sun, J., Jiang, W.J., Libinaka, R., and Gianello, R. (2000). Metabolic Studies of a Synthetic Lipolytic Domain (AOD-9604) of Human Growth Hormone.
  3. Heffernan, M., Ng, F.M., Summers, R.J., Thorburn, A., et al. (2001). The Effects of Human GH and its Lipolytic Fragment (AOD-9604) on Lipid Metabolism Following Chronic Treatment in Obese Mice and β3-AR Knock-Out Mice.
  4. Heffernan, M., Gianello, R., Ng, F.M., et al. (2001). Increase of Fat Oxidation and Weight Loss in Obese Mice Caused by Chronic Treatment with Human Growth Hormone or a Modified C-Terminal Fragment. International Journal of Obesity.

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