Ganirelix

July 20, 2023

Ganirelix is an injectable competitive gonadotropin-releasing hormone antagonist (a decapeptide GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation. Ganirelix is marketed by Merck & Co., Inc. as Orgalutran.
Ganirelix is rapidly absorbed following subcutaneous injection with maximum serum concentrations reached approximately one hour after dosing.


Status:In Mass Production
Unit:5mg,10mg,1g/customized
Capacity: 1kg/month

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Raw Ganirelix powder (124904-93-4) video

Ganirelix Description

Ganirelix is an injectable competitive gonadotropin-releasing hormone antagonist (a decapeptide GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation. Ganirelix is marketed by Merck & Co., Inc. as Orgalutran.

Ganirelix is rapidly absorbed following subcutaneous injection with maximum serum concentrations reached approximately one hour after dosing.

Ganirelix Specifications

Product NameGanirelix
Chemical NameAc-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Ganirelixum
Brand NameOrgalutran, Antagon
Drug ClassPeptide
CAS Number124904-93-4 (123246-29-7)
InChIKeyGJNXBNATEDXMAK-PFLSVRRQSA-N
Molecular FormulaC80H113ClN18O13
Molecular Weight1570.347 g/mol
Monoisotopic Mass1568.842 g/mol
Melting Point N/A
Biological Half-Life16.2 hours
ColorWhite
Solubility 0.25mg/ml~30mg/ml in DMSO and DMF
Storage Temperature −20°C
Applicationa Gonadotropin Releasing Hormone Antagonist, used in assisted reproduction to control ovulation.


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