NSI-189 base (1270138-40-3) video
NSI-189 base (1270138-40-3) Description
NSI-189 base is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine. That was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro. In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression. The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer’s disease, and major depressive disorder (MDD).
NSI-189 base (1270138-40-3) Specifications
|Product Name||NSI-189 base|
|Chemical Name||(4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone; UNII-YVE9U408ZL; YVE9U408ZL;|
|Brand Name||NSI-189 base|
|Drug Class||Inhibitors; Nootropic|
|Molecular Weight||366.509 g/mol|
|Monoisotopic Mass||366.242 g/mol|
|Biological Half-Life||17.4 – 20.5 hours|
|Solubility||10 mM in DMSO|
|Storage Temperature||Cool Dry Place|
|NSI-189 base Application||It is used for treating other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.|