Raw NSI-189 Phosphate powder (1270138-41-4)

December 28, 2018

Raw NSI-189 Phosphate powder is a multi-domain neurogenic compound with brain-therapeutic properties with potential…….


Status:In Mass Production
Unit:25kg/Drum
Capacity:1530kg/month

 

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Raw NSI-189 Phosphate powder (1270138-41-4) video

 

Raw NSI-189 Phosphate powder (1270138-41-4)Description

Raw NSI-189 Phosphate powder is neurogenic and nootropic research agent that was developed from nicotinamide and pyrazine. Randomized controlled trials have shown that it stimulates neurogenesis or neuronal cell production in the brain.

In animal studies, it has also been shown to increase the volume of hippocampus by 20% thereby reversing behavioral symptoms of depression. Such studies have shown that it may be an effective treatment for depression.

Raw NSI-189 Phosphate powder is also thought to be a promising treatment for other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.

Raw NSI-189 Phosphate powder (1270138-41-4) Specifications

Product NameRaw NSI-189 Phosphate powder
Chemical NameUNII-HX0VO60T62;HX0VO60T62;AKOS030632361;Methanone,(2-((3-methylbutyl)amino)-3-pyridinyl)(4-(phenylmethyl)-1-piperazinyl)-, phosphate (1:1)
Brand NameRaw NSI-189 Phosphate powder
Drug ClassNootropic
CAS Number1270138-41-4
InChIKeyLWHMGALTTIYPJU-UHFFFAOYSA-N
Molecular FormulaC22H33N4O5P
Molecular Weight464.503 g/mol
Monoisotopic Mass464.219 g/mol
Melting PointN/A
Biological Half-LifeN/A
ColorWhite to off white
Solubility N/A
Storage Temperature Room temperature
Fasoracetam ApplicationIt is used for treating other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.

 

Raw NSI-189 phosphate powder (1270138-41-4)

Raw NSI-189 Phosphate powder is neurogenic and nootropic research agent that was developed from nicotinamide and pyrazine. Randomized controlled trials have shown that it stimulates neurogenesis or neuronal cell production in the brain.

In animal studies, it has also been shown to increase the volume of hippocampus by 20% thereby reversing behavioral symptoms of depression. Such studies have shown that it may be an effective treatment for depression.

Raw NSI-189 Phosphate powder is also thought to be a promising treatment for other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.

NSI-189 phosphate powder (1270138-41-4) Mechanism of actions?

The mechanism of action of NSI-189 phosphate remains a trade secret. It has been speculated that NSI-189 binds to the glucocorticoid receptor in the brain. Glucocorticoid receptor binding could be form of negative feedback that decreases circulating cortisol. Cortisol is a stress hormone implicated in depression and other stress-related neuropsychiatric disorders.

Benefits of NSI-189 phosphate powder (1270138-41-4)

NSI-189 is a nootropic compound currently being studied by Neuralstem in order to use it to treat several psychiatric disorders like depression and neurodegenereative diseases.

  • May Improve Cognition
  • May Improve Depression
  • May Help With Stroke
  • May Help With Diabetes

Recommended NSI-189 phosphate powder (1270138-41-4) Dosage

Due to the fact that NSI-189 phosphate powder is still a trial drug, there has not yet been a fixed dosage. However, during the trials patients were given daily doses of 40mg, 80mg, and 120mg at the highest dose per day over the course of 28 days. During this period, patients did not report any serious events or side effects, and the NSI-189 phosphate was found to be well tolerated. Also, there was a significant reduction in depression and cognitive symptoms for patients taking the lower doses of 40mg and 80mg, but not for those taking 120mg per day. The preliminary findings of the trials are supportive of the idea that NSI-189 phosphate can treat MDD. Nonetheless, further studies on the dosage and the method of action of NSI-189 phosphate are imperative to help confirm preliminary observations and help draw conclusions.

Side effects of NSI-189 phosphate powder (1270138-41-4)

Side effects reported have been dry mouth, palpitations, headaches, dizziness, sleepiness, fatigue, restlessness, poor quality of sleep, nightmares/vivid dreams, parathesia, insomnia, hyperthermia, nausea, skin pain, and rash.

 

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