Urolithin B

April 8, 2021

Urolithin B decreases protein degradation and induces muscle hypertrophy. Urolithin B inhibits the activity of aromatase, an enzyme that interconverts estrogen and testosterone.

Chemical information of Urolithin B

Product Name Urolithin B powder
Chemical Name 3-hydroxy-6H-benzo[c]chromen-6-one

3-hydroxybenzo[c]chromen-6-one

Uro-B

3-Hydroxyurolithin

CAS Number 1139-83-9
InChIKey WXUQMTRHPNOXBV-UHFFFAOYSA-N
SMILE C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
Molecular Formula C13H8O3
Molecular Weight 212.2 g/mol
Monoisotopic Mass 212.047344 g/mol
Melting Point 247 °C
Color white to beige powder
Solubility DMSO: soluble5mg/mL, clear (warmed)
Storage temp 2-8°C
Application Urolithin B has been used in bodybuilding and supplements area.

Reference

[1] Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57. [2]. Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):583-597.

[2] Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia.Lee G, Park JS, Lee EJ, Ahn JH, Kim HS.

[3] Urolithin B, a newly identified regulator of skeletal muscle mass.Rodriguez J, Pierre N, Naslain D, Bontemps F, Ferreira D, Priem F, Deldicque L, Francaux M.

[4] Urolithin B, a gut microbiota metabolite, protects against myocardial ischemia/reperfusion injury via p62/Keap1/Nrf2 signaling pathway.Zheng D, Liu Z, Zhou Y, Hou N, Yan W, Qin Y, Ye Q, Cheng X, Xiao Q, Bao Y, Luo J, Wu X.