Urolithin A 8-Methyl Ether（35233-17-1）video
Urolithin A 8-Methyl Ether（35233-17-1）Specifications
| Product Name | Urolithin A 8-Methyl Ether powder |
| Chemical Name | 3-hydroxy-8-methoxy-6H-benzo[c]chromen-6-one;
3-hydroxy-8-methoxybenzo[c]chromen-6-one; 35233-17-1; MLS001049096; SMR000386929; ChemDiv3_002724; Urolithin A 8-Methyl Ether; |
| CAS Number | 35233-17-1 |
| InChIKey | IGJLBTGXYKPECW-UHFFFAOYSA-N |
| Molecular Formula | C14H10O4 |
| Molecular Weight | 242.23 |
| Monoisotopic Mass | 242.057909 g/mol |
| Melting point | 242 °C(Solv: acetic acid (64-19-7)) |
| Boiling point | 479.9±38.0 °C(Predicted) |
| Density | 1.375±0.06 g/cm3(Predicted) |
| Biological Half-Life | N/A |
| Color | Light Beige to Very Dark Orange Solid |
| Solubility | Acetone (Slightly, Sonicated) DMSO (Slightly, Sonicated), Methanol (Slightly) |
| Storage Temperature | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Application | Urolithin A 8-Methyl Ether is an intermediate in the synthesis of Urolithin A (U847000), a major metabolite of Ellagitannin and exhibits anti-inflammatory and antioxidant properties. |
Reference
[1] Espín, Juan Carlos; Larrosa, Mar; García-Conesa, María Teresa; Tomás-Barberán, Francisco (2013). “Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far”. Evidence-Based Complementary and Alternative Medicine. 2013: 270418. doi: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.
[2] Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Pénélope A; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Félix, Amandine A; Williams, Evan G; Jha, Pooja; Sasso, Giuseppe Lo (2016). “Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents”. Nature Medicine. 22(8): 879–888. doi:1038/nm.4132. PMID 27400265.
[3] Ishimoto, Hidekazu; Shibata, Mari; Myojin, Yuki; Ito, Hideyuki; Sugimoto, Yukio; Tai, Akihiro; Hatano, Tsutomu (2011). “In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A”(PDF). Bioorganic & Medicinal Chemistry Letters. 21(19): 5901–5904. doi:1016/j.bmcl.2011.07.086. PMID 21843938.
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