Ganirelix Acetate

July 20, 2023

Ganirelix Acetate is the acetate salt form of ganirelix, a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix directly competes with the GnRH for receptor binding in the anterior pituitary gland, thus induces a rapid and reversible suppression of the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH). This agent is used for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation, and in combination with other hormones for retrieval of the mature follicles for in-vitro fertilization.


Status:In Mass Production
Unit:5mg,10mg,1g/customized
Capacity: 1kg/month

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Raw Ganirelix Acetate powder (129311-55-3) video

Ganirelix Acetate Description

Ganirelix Acetate is the acetate salt form of ganirelix, a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix directly competes with the GnRH for receptor binding in the anterior pituitary gland, thus induces a rapid and reversible suppression of the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH). This agent is used for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation, and in combination with other hormones for retrieval of the mature follicles for in-vitro fertilization.

Ganirelix Acetate Specifications

Product NameGanirelix Acetate
Chemical NameN-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate
Brand NameOrgalutran, Antagon
Drug ClassPeptide
CAS Number129311-55-3
InChIKeyOVBICQMTCPFEBS-SATRDZAXSA-N
Molecular FormulaC84H121ClN18O17
Molecular Weight1690.45
Monoisotopic Mass1688.8845622
Melting Point N/A
Biological Half-LifeN/A
ColorWhite
Solubility 0.25mg/ml~30mg/ml in DMSO and DMF
Storage Temperature −20°C
Applicationused for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation, and in combination with other hormones for retrieval of the mature follicles for in-vitro fertilization.

 


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