Sermorelin

March 2, 2024
SKU: 86168-78-7

Phcoker is a professional Sermorelin GMP manufacturer that provide both form of Sermorelin powder and Sermorelin finished lyophilized powder in vial.  The regularly manufacturing specification include Sermorelin 5mg, Sermorelin 10mg, Sermorelin 15mg. Larger dosage and contract manufacturing service is available.

Monthly production capacity: >1,000,000 vials


Other Name:Sermorelinum,86168-78-7,Sermorelina,SCHEMBL34139,UNII-8,243S03TE,DTXSID70903978,EX-A5534,BDBM50004966,89243S03TE,AC-8930

 

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Raw Sermorelin powder (86168-78-7) video

 

Properties


Sequence:H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Molecular Formula:C149H246N44O42S
Molecular Weight:3357.9 g/mol
PubChem CID:16132413
CAS Number:86168-78-7
Synonyms:Sermorelinum,86168-78-7,Sermorelina,SCHEMBL34139,UNII-8,243S03TE,DTXSID70903978,EX-A5534,BDBM50004966,89243S03TE,AC-8930

Description


Sermorelin peptide is a man-made synthetic peptide that stimulates the pituitary gland to release growth hormone. As an analog of growth hormone-releasing hormone, Sermorelin’s primary role is as a treatment that stimulates the body to release enough growth hormone to act as a treatment for children who are unable to grow normally. In addition, Sermorelin can also accelerate wound healing, increase muscle mass and other effects.

What Is Sermorelin Peptide

Before view the details of Sermorelin, we need to know what is Growth Hormone-Releasing Hormone first. Growth hormone-releasing hormone (GHRH) is a hypothalamic peptide hormone that stimulates the pituitary gland to secrete growth hormone. [1][8]When GHRH binds to specific receptors on the cells of the anterior pituitary gland, it triggers a biochemical reaction in the pituitary gland, thereby stimulating the release of growth hormone into the blood.

The secretion of growth hormone is very important in the regulation of various physiological processes. Whether it is growth and development during childhood and youth, or metabolism and muscle growth in adulthood, GHRH plays an extremely important role in the entire process of body growth and development. big effect.

Sermorelin peptide is a well-tolerated GHRH analog that binds to receptors in the brain to stimulate the release of growth hormone. In terms of treatment, Sermorelin powder is the active ingredient of Sermorelin-based products, which is mainly used to diagnose and treat growth hormone deficiency in children and adults, and to stimulate the growth and development of the body. In addition, Sermorelin can also be used for anti-aging and improving sports performance.[3][6]

To achieve the benefits of Sermorelin,researchers buy Sermorelin peptide from pharmacy or peptide manufacturers online, and found that it is cheaper to buy online. The good manufacturers of peptides, they will have perfect quality management system to guarantee the quality of Sermorelin peptides is genius. Not only can manufacture Sermorelin powder but can provide customized production to match different customers’ requirements, especially the peptide retailers or peptide independent brand owner.

The Structure Of Sermorelin Powder

Structure Sermorelin Powder

The Mechanism Action Of Sermorelin

Sermorelin peptide is a natural GHRH analogue that stimulates the growth hormone-releasing hormone receptor in the anterior pituitary gland to release growth hormone. [11][13]The following is the main mechanism of action of Sermorelin:

Binding to GHRH receptors: Sermorelin peptide can bind to receptors on anterior pituitary cells, and GHRH naturally produced in the human body can activate these receptors.

Stimulates the release of growth hormone: Sermorelin can stimulate the pituitary gland to release growth hormone after binding to the receptor, and causes the synthesis and release of these growth hormones into the body’s blood.

Regulate body circulation: The release of growth hormone itself is feedback-regulated by various mechanisms in the body. On the contrary, the release of growth hormone can also adjust the level of growth hormone in the body to an appropriate level.

Produce physiological effects: After growth hormone is released into the blood, it will affect the body’s tissues and organs, stimulating the body’s physiological reactions, including body growth and development, metabolism and other physiological effects.

Researchers seeking to know more about the science behind Sermorelin prefer to buy Sermorelin powder from Sermorelin powder manufacturers online, due to the fast shipping and easy order process, what is important, the Sermorelin price is more competitive than pharmacy. But make sure to buy from the legal peptide manufacturer like Phcoker.

The Benefits Of Sermorelin Powder

Sermorelin powder is a synthetic hormone peptide.[2][4][5]As a professional peptide manufacturer, Phcoker can provide you with high-quality Sermorelin powder. After receiving Sermorelin injection, here are 10 primary expected benefits of Sermorelin, including:

  • Stimulates growth hormone secretion: Sermorelin powder can stimulate the pituitary gland to release growth hormone, thus having a therapeutic effect on growth hormone deficiency in children and adults.
  • Promote growth and development: For patients who are deficient in growth hormone, Sermorelin can stimulate bone growth and development, thereby increasing height and the growth and development of other tissues.
  • Promote weight loss: Sermorelin can promote metabolism. The increase in metabolism increases the burning of calories, thereby increasing fat-free weight and helping to lose weight.
  • Increase muscle: Muscle protein is an important component of muscles, and after stimulating the secretion of growth hormone, Sermorelin can promote tendon and skeletal muscle mass, thereby increasing your muscle strength and size.
  • Increase insulin sensitivity: Studies have shown that Sermorelin can increase insulin sensitivity, improve blood sugar control in patients, and reduce the risk of type 2 diabetes.
  • Increased libido: Low growth hormone can reduce sexual desire levels, and as hormone levels drop, sexual relationships can become more complicated. Sermorelin is an effective treatment option for restoring libido and treating any sexual dysfunction.[11][12]
  • Improve bone health: Sermorelin can promote calcium retention and bone mineralization, which is very helpful for bone self-repair and can increase bone density, thereby reducing the chance of osteoporosis.
  • Enhance immunity: Sermorelin injection can affect cell regeneration and increase the number of red blood cells and white blood cells, thereby increasing and improving your immunity and immune system.
  • Effective anti-aging: Sermorelin treatment can tighten the skin and restore skin aging. And through the injection of Sermorelin, the skin can absorb more moisture, making the skin plumper and firmer.
  • Increase energy levels: Sermorelin promotes lipolysis, and the broken down fat is converted into energy. Therefore, Sermorelin can effectively improve energy, mental health and mood.

Sermorelin peptide be sold online under different brand name, but the active ingredient of all Sermorelin brand is Sermorelin powder

Sermorelin Vs HGH: Differences, Similarities

As the best sell peptides, why are Sermorelin and HGH often put together?Let’s have a deep research on the differences and similarities between Sermorelin and HGH(Human Growth Hormone).

What is Sermorelin peptide?

Sermorelin is a growth hormone-releasing analog that stimulates the pituitary gland to produce more growth hormone.[7][10]Treatment with Sermorelin can restore hormone levels to a more youthful state.

What is HGH?

HGH is a natural substance produced by the pituitary gland. Growth hormone stimulates body growth. However, as age increases, HGH levels will gradually decrease, so some HGH supplements need to be used accordingly.

How do you compare Sermorelin and HGH?

Although the ultimate goal of Sermorelin and HGH is to increase growth hormone levels, they do so in different ways. The main differences are:

Sermorelin increases hormone production by stimulating the pituitary gland, causing the body to naturally produce more growth hormone.

HGH increases growth hormone levels by injecting synthetic HGH into the body.

Why Are Sermorelin Injections More Effective Than Hormone Replacement Therapy?

Sermorelin injections provide individuals with human growth hormone-releasing chemicals in cases where the body’s natural production is insufficient. Understanding the benefits of sermorelin involves recognizing its capacity to elevate human growth hormone levels, essential for bodily repair and facilitating weight loss through metabolism acceleration, appetite suppression, and enhanced fat burning facilitated by hormone replacement therapy (HRT). Why Sermorelin injection is more effective than HRT? The primary reason may include:

  • Can increase GH levels more effectively

Sermorelin can stimulate the pituitary gland to secrete more growth hormone release. One injection of Sermorelin can increase GH levels for up to six hours, and repeated injections can increase the time for up to two weeks.

  • Fewer Side Effects

Sermorelin stimulates the body’s natural release of growth hormone, so it doesn’t cause side effects like the synthetic growth hormone supplements we’re talking about.

  • Sermorelin is cheaper

For most people, hormone replacement therapy is very expensive, and Sermorelin is more cost-effective. As a professional peptide manufacturer, Phcoker.com can provide you with preferential prices for Sermorelin.[9][13]

As a long-term health maintenance, the cost of purchasing Sermorelin is undoubtedly an expensive expense. Individual seeking Sermorelin for body health turn to buy Sermorelin online, especially from the professional peptide manufacturers, Phcoker is one of the popular peptide manufacturers in 2024.

What Are The Side Effects Of Sermorelin Injections?

Although Sermorelin is generally considered safe and well-tolerated by most people, it is important to fully understand its possible side effects before using it so that you can respond promptly. These side effects include:

Common side effects

Injection site reaction: Redness

Swelling

Pain

Itching

These reactions are mild and can go away without even taking any action.

Uncommon side effects

Dizziness

Nausea

Flushing

Rash

Hard to swallow

Sermorelin For Sale | Sermorelin Supplier

Sermorelin original powder is a synthetic compound containing 28 amino acid peptide analogues of growth hormone-releasing hormone, which has biological activities of immunomodulation and promoting angiogenesis. Sermorelin injection has a significant regulatory effect on various physiological responses such as muscle increase and fat loss.

lf you’re looking to buying Sermorelin online, it is essential to exercise caution and ensure that you obtain the peptide from a reputable and trustworthy manufacuturer. Phcoker is a highly reliable manufacturer that offers pharmaceutical grade peptides.

 

Manufacturers/Factory


Sermorelin is a natural growth hormone-releasing hormone that can stimulate the body’s secretion and release of human growth hormone. The use of Sermorelin can have many benefits in restoring growth hormone levels. As we age, growth hormone will become less and less. Through Sermorelin treatment, the level of growth hormone in the body will be increased, stimulating the growth and development of the body and many other benefits. Currently, more and more people on the market are interested in this peptide.

As the best Sermorelin peptide manufacturer, Phcoker is not only supply the peptide Sermorelin in powder form but provide the customized standard easy use vial form.

You can buy the best price Sermorelin and best quality peptide from this professional peptide manufacturer.

 

Where to buy


Would you like to buy the best Sermorelin peptide from the best Sermorelin suppliers in the market? You have come at the right place!

Phcoker as a peptide factory, is the best place where you can buy Sermorelin in compeptitive price, from small to bulk quantity. Click and make a contact, you will get all the details. Before buy Sermorelin, you may curious:

What Are The Advantages If Buy Sermorelin From Phcoker.com?

  • 【Competitive Factory Price】

Factory direct sales, No middlemen make a difference.

  • 【Customization Service】

Product specifications can be customized to create your own peptide brand.

  • 【Quality Guarantee】

Professional lab reports along with shipment.

  • 【Fast Shipping】

Professional logistics customization solutions, on-time delivery.

  • 【Easy Payment】

Payment methods that are diverse.

  • 【365/24/7 Service】

High quality pre-sales and after-sales service, followed by product and order details consultation.

How To Get The Quick Price Of Sermorelin Online?

  • Visit professional Sermorelin supplier Phcoker.com, choose the Sermorelin you want to buy.
  • Leave your contact and message on Phcoker website, then submit to Phcoker.com.
  • The customer service will reply you in 12 hours once received your message, then talk in details about buy Sermorelin.

Does Phcoker.com Support The Free Sample Of Sermorelin Powder?

It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for sample.

Can I Appoint The Sermorelin Colour When Buy Sermorelin?

YES! Phcoker as peptide manufacturer, provide colour customization of Sermorelin, easy to help you to build your Sermorelin peptide brand.

Can I Appoint The Products Standard When Buy Sermorelin From Phcoker.com?

YES! As one of the best Sermorelin manufacturer, Phcoker not only provide the standard specification of Sermorelin in 5mg, 10mg, but support standard customization. Provide the best support to build your own Sermorelin brand.

Can I Buy Sermorelin In Pure Powder Form From Phcoker.com?

YES! Sermorelin powder is the base that use for Sermorelin lyophilized powder manufacture. Phcoker provide Sermorelin in both of pure powder form and semi-finished vial form.

Can I Buy Discount Sermorelin Powder From Phcoker.com?

YES! Our factory produce high quality Sermorelin powder in term and keep Sermorelin powder in stock. You can buy high quality Sermorelin powder in bulk. During promotion sale, you can buy Sermorelin peptide by lower price. You can keep touch with our customer manager and they will update the latest bulk Sermorelin price for you in time.

 

FAQ


What is Sermorelin used for?

Sermorelin mainly stimulates the release of growth hormone and is mainly used for the diagnosis and treatment of growth hormone deficiency in children and adults.

When should Sermorelin be administered?

Since growth hormone is usually released during sleep, the best time to use Sermorelin is before bed, which is very beneficial to the body’s recovery.

How to use Sermorelin?

Sermorelin is usually administered by subcutaneous injection, normally once a week, but dosage and exact frequency vary based on individual factors and requires consultation with a healthcare professional.

How long does it take for Sermorelin to work?

Like most supplements, Sermorelin takes 3-6 months to see the full effect. Its mechanism of action relies on the body’s reaction process, so it takes a certain amount of time to reach optimal levels.

Is lifelong use of Sermorelin necessary to achieve the desired results?

unnecessary. The maintenance effect of Sermorelin is very good, and the frequency of injections can be reduced or stopped after reaching optimal levels. At this time, the patient can switch to a maintenance regimen without the need for daily injections.

What does Sermorelin look like?

Phcoker.com offers Sermorelin as original powder or as lyophilized powder in injectable vials.

Is Sermorelin safer than HGH?

Sermorelin stimulates the production and release of growth hormone. Not only is it cheaper than HGH, it is also safer.

Do bodybuilders use Sermorelin?

Supplements commonly used by athletes include: Sermorelin, Tesamorelin, CJC 1295 with DAC, CJC 1295 without DAC, Anamorelin, etc.

Does Sermorelin Make You Younger?

Sermorelin works against skin and wrinkles, helping the skin return to a healthier condition and appearance, making you look younger.

Will Sermorelin Reduce Belly Fat?

Sermorelin can promote the body’s metabolism. Although it is not a professional weight loss drug, its potential effect can be to reduce abdominal visceral fat.

Referenced Citations


[1]Grønning AGB, Kacprowski T, Schéele C.MultiPep: a hierarchical deep learning approach for multi label classification of peptide bioactivities.Biol Methods Protoc. 2021 Nov 23;6(1):bpab021. doi: 10.1093/biomethods/bpab021. eCollection 2021.PMID: 34909478.

[2]Chang Y, Huang R, Zhai Y, Huang L, Feng Y, Wang D, Chai R, Zhang W, Hu H.A potentially effective drug for patients with recurrent glioma: sermorelin.Ann Transl Med. 2021 Mar;9(5):406. doi: 10.21037/atm-20-6561.PMID: 33842627 .

[3]Mi YN, Ping NN, Cao YX.Ligands and Signaling of Mas-Related G Protein-Coupled Receptor-X2 in Mast Cell Activation.Rev Physiol Biochem Pharmacol. 2021;179:139 188. doi: 10.1007/112 2020 53.PMID: 33479839.

[4]Sinha DK, Balasubramanian A, Tatem AJ, Rivera Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI.Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Transl Androl Urol. 2020 Mar;9(Suppl 2):S149 S159. doi: 10.21037/tau.2019.11.30.PMID: 32257855.

[5]Prakash A, Goa KL (August 1999). Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 12 (2): 139 57. doi:10.2165/00063030-199912020 00007. PMID 18031173. S2CID 195690081.

[6]Pharmacology (Rang, Dale, Ritter & Moore, ISBN 0-443-07145-4, 5th ed., Churchill Livingstone 2003).

[7]Fahy J.2006Drug could fight effects of aging [online]Accessed on 22 June 2006. Pittsburgh Post-Gazette. URL: http://www.post-gazette.com/pg/06173/700274-114.stm.

[8]Landsmann MA. Forever young What role does human growth hormone play in the aging process The question is rife with controversy. ADVANCE for Healthy Aging. 2006;2:54 61. [Google Scholar]

[9]Walker RF, Eichler DC, Bercu BB. Inadequate pituitary stimulation: a possible cause of growth hormone insufficiency and hyperprolactinemia in aged rat. Endocrine. 1994;2:633 8. [Google Scholar]

[10]Villalobos C, Núñez L, Frawley LS, et al. Multi responsiveness of single anterior pituitary cells to hypothalamic releasing hormones: A cellular basis for paradoxical secretion. Proc Natl Acad Sci U S A. 1997;94:14132 7. [PMC free article] [PubMed] [Google Scholar]

[11]Russell Aulet M, Dimaraki EV, Jaffe CA, et al. Aging related growth hormone (GH) decrease is a selective hypothalamic GH releasing hormone pulse amplitude mediated phenomenon. J Gerontol A Biol Sci Med Sci. 2001;56:M124 9. [PubMed] [Google Scholar]

[12]Perls TT, Reisman NR, Olshansky SJ. Provision and distribution of growth hormone for antiaging: clinical and legal issues. JAMA. 2005;294:2086–90. [PubMed] [Google Scholar]

[13]Merriam GR, Barness S, Buchner D, et al. Growth hormone releasing hormone treatment in normal aging. J Anti-Aging Med. 2001;4:331 43. [Google Scholar]

 

Author of this article:


Dr. Jean Zeng graduated from king’s college london Faculty of Life Sciences & Medicine.

 

Scientific Journal paper Author:


1.B.L. Furman

Strathclyde Institute of Pharmacy and Biomedical Sciences, Glasgow, United Kingdom

2.Cătălina-Diana Cristea

University of Bucharest, Faculty of Chemistry, Department of Analytical and Physical Chemistry, Sos. Panduri, No. 90, Sect 5, Bucharest, 050663, Romania

3.Gilles Coppieters

Doping Control Laboratory (DoCoLab), Ghent University, Department of Diagnostic Sciences (GE32), Ottergemsesteenweg 460, B-9000 Ghent, Belgium

4.Laura Pont

Catalonian Antidoping Laboratory, IMIM, Hospital del Mar Medical Research Institute, Barcelona, Spain

5.Steven Janvier

Division of Food, Medicines and Consumer Safety, Section Medicines and Healthcare Products, Scientific Institute of Public Health (WIV-ISP), J. Wytsmansstraat 14, B-1050 Brussels, Belgium


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