Ipamorelin

March 2, 2024

Phcoker is a professional Ipamorelin GMP manufacturer that provide both form of Ipamorelin powder and Ipamorelin finished lyophilized powder in vial.  The regularly manufacturing specification include Ipamorelin 10mg,Ipamorelin 20mg, Ipamorelin 30mg. Larger dosage and contract manufacturing service is available.

Monthly production capacity: >1,000,000 vials


Other Name:SCHEMBL18428173,DTXSID80168955,A881983,NNC 26-0161

 

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Raw Ipamorelin powder (170851-70-4) video

Properties


Sequence:(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(4H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Molecular Formula:C38H49N9O5
Molecular Weight:711.9 g/mol
PubChem CID:20754357
CAS Number:170851-70-4
Synonyms:SCHEMBL18428173,DTXSID80168955,A881983,NNC 26-0161

Description


Ipamorelin peptide was originally developed by Novo Nordisk and was initially used to treat postoperative intestinal obstruction. As a pentapeptide, it is also a ghrelin/ghrelin receptor agonist. As a ghrelin, it can not only promote weight loss, increase muscle mass and improve sleep, but also maintain bone health and reduce the impact of glucocorticoids. If you are interested in buying or knowing more about Ipamorelin,here is the updated complete guide of Ipamorelin in 2024.

The Structure of Ipamorelin Peptide

Structure Ipamorelin Peptide

What Is Ipamorelin Powder?

Ipamorelin is also known as “Growth Hormone Releasing Peptide (GHRP)” and is considered to be one of the safest GHRP drugs.[1][5]Growth Hormone Releasing Peptiden can slowly and steadily mimic the natural release of growth hormone, while also achieving a more intense self-induced release of growth hormone through the stimulation of ghrelin.

Ipamorelin powder is the active ingredient of Ipamorelin-based pharmaceutical products, it is not only stimulates growth hormone secretion, but also inhibits the hormone somatostatin.The more growth hormone you have in your body, the younger you will be. This dual role of Ipamorelin peptide removes obstacles that hinder the production of growth hormone and greatly increases the release rate of growth hormone.

Researchers seeking to purchase Ipamorelin powder for their peptide studies will discover that buying Ipamorelin online is cost-efficient option. However,it is a challenge to identify a reputable manufacturer from the sea of peptide suppliers.

How Dose Ipamorelin Work?

Ipamorelin mainly works by imitating the growth hormone-releasing peptide in the body. Ghrelin, which was discovered in 1999, has a great impact on the body’s metabolism and can regulate the release of hormones.[3][6]

This effect of Ipamroelin is very helpful for appetite regulation and energy release. This naturally occurring hormone in the gastrointestinal system binds to ghrelin receptors and stimulates the pituitary gland to release growth hormone.

The main appeal of Ipamorelin’s popularity is its selectivity. Its ability to precisely target growth hormone-releasing receptors allows users to wean themselves off a wider range of hormones, thereby avoiding some of the common adverse side effects of growth hormone therapy.

Ipamorelin can help users achieve physical goals such as muscle growth by creating a more favorable synthetic environment.[2]

If you are interested in studying the benefits, mechanism of action, etc. of Ipamorelin, you can try to purchase some Ipamorelin for more in-depth exploration.

Benefits of Ipamorelin

Ipamorelin powder is a synthetic form of ghrelin that has a variety of health benefits, including weight loss and anti-aging benefits. Here are top 8 benefits of Ipamorelin in 2024:

  • Weight Loss: Ipamorelin powder can promote fat loss through increased metabolism and breakdown of fat cells. Ipamorelin not only reduces fat mass, but also preserves muscle quantity and quality, providing users with a healthy way to lose weight.
  • Muscle Gaining: Ipamorelin has been widely used as a muscle-building supplement to promote the release of growth hormone, which promotes protein synthesis, thereby helping to enhance muscle mass and growth.
  • Anti-aging: Researchers have found that Ipamorelin helps promote collagen synthesis. Regular use of Ipamorelin powder can help reduce the appearance of aging and maintain skin firmness and elasticity.[7][14]
  • Improves intestinal health: Ipamporelin improves intestinal barrier function, thereby improving intestinal health. In addition, Ipamorelin can also regulate intestinal peristalsis and reduce inflammation.
  • Maintain bone health: Ipamorelin, like GH, can promote the enhancement of bone density. Bone density refers to the amount of minerals and protein in the bone tissue in our body. Ipamorelin can promote bone growth and remodeling and maintain bone health.
  • Enhances cognitive abilities: Ipamorelin also helps improve cognitive abilities by stimulating the release of growth hormone, which improves memory and learning abilities.
  • Strengthens the Immune System: Ipamorelin can improve the body’s immune system function by regulating the response to infection and inflammation, and may also improve overall recovery.
  • Improves vitality and energy: Ipamorelin stimulates growth hormone levels to increase energy and vitality.[4][13]

CJC 1295 + Ipamorelin: What Are The Advantages?

Recently, with the advancement of medical technology, medical research has brought about combination therapy of peptides. The combination of CJC 1295 and Ipamorelin can significantly improve appearance and health.

Why should CJC 1295 and Ipamorelin be used together?

The combined use of CJC 1295 and Ipamorelin increases the release of growth hormone by 3-5 times compared to Ipamorelin alone. In addition, the half-life of Ipamorelin is 2 hours, and the addition of CJC 1295 makes the drug effect last longer.[9][11]

What are the benefits of the combined use of CJC 1295 and Ipamorelin?

  • Faster onset of action: This combined effect accelerates the rapid release of growth hormone, allowing the body to obtain more energy.
  • Longer-lasting effects: The addition of CJC 1295 extends the time it takes for Ipamorelin to take effect, giving it long-term benefits.
  • Reduces Hormone Infections: This combined approach keeps cortisol and other hormone levels from being affected, which is important for overall health.

Ipamorelin VS Sermorelin: Which One Is Better?

What is Sermorelin?

Sermorelin is a ghrelin analog, a synthetic version of ghrelin that stimulates the release of growth hormone.

What is Ipamorelin?

Ipamorelin is a pentapeptide, a ghrelin that can stimulate the release of growth hormone and inhibit the release of somatostatin.

What’s the difference between the two?

  • The constituent genes are different: Ipamorelin is a pentapeptide with relatively few amino acids; while Sermorelin is a large peptide containing 29 amino acids.
  • The mechanisms of action are different: Ipamorelin is designed to mimic ghrelin, which can stimulate the release of growth hormone; Sermorelin has a mechanism of action similar to GHRH, which stimulates the production of natural growth hormone.
  • The administration methods are different: Ipamorelin has fewer peptide blocks and is mainly administered subcutaneously; Sermorelin has more amino acids and can only be administered by injection.

What are the Side Effects of Ipamorelin Powder?

Ipamorelin is well tolerated, although Ipamorelin peptides offer many benefits and uses to users.[8][15]However, you should also be aware of the potential side effects it may bring when using it.

Common side effects include:

  • injection site reactions
  • Headache
  • nausea
  • flushing

Uncommon side effects:

  • Dizziness
  • abdominal discomfort
  • fatigue

Although the purity and quality of the product provided by Ipamorelin supplier Phcoker.com are superior, the side effects it brings cannot be ignored. If serious side effects occur, you should consult a medical professional to ensure the safety and effectiveness of the medication.[10][12]

Ipamorelin For SaleIpamorelin Manufacturer

Ipamorelin is a very powerful peptide and a hormone secretagogue that can significantly enhance growth hormone (GH) levels in plasma. Ipamorelin powder does not stimulate the secretion of adrenocorticotropic hormone and cortisol, but its main purpose is to stimulate the pituitary gland to secrete growth hormone. This hormone is necessary for various physiological activities (growth, metabolism, etc.). Ipamorelin can promote weight loss, increase muscle mass and growth, fight aging, improve bone density, and many other benefits.

With the advancement of technology, there are currently many suppliers on the market offering Ipamorelin peptides. However, when buying Ipamroelin online, you need to find a reliable and trustworthy manufacturer. Phcoker is a professional Ipamorelin manufacturer that can provide pharmaceutical grade Ipamorelin raw powder and Ipamorelin lyophilized powder in vials. If you want to buy Ipamorelin, Phcoker.com is a good place you can visit.

 

Manufacturers/Factory


Ipamorelin is a synthetic peptide belonging to the GHRP family, which stimulates the secretion of growth hormone and has potential benefits and uses. Ipamorelin is currently used by athletes as a specific drug to provide performance. Ipamorelin, when used correctly and under the guidance of a healthcare practitioner, can help resolve health problems and may also promote overall well-being.

As the best Ipamorelin peptide manufacturer, Phcoker is not only supply the peptide Ipamorelin in powder form but provide the customized standard easy use vial form.

You can buy the best price Ipamorelin and best quality peptide from this professional peptide manufacturer.

Where to buy


Would you like to buy the best Ipamorelin peptide from the best Ipamorelin suppliers in the market? You have come at the right place!

Phcoker as a peptide factory, is the best place where you can buy Ipamorelin in compeptitive price, from small to bulk quantity. Click and make a contact, you will get all the details. Before buy Ipamorelin, you may curious:

What Are The Advantages If Buy Ipamorelin From Phcoker.com?

  • 【Competitive Factory Price】

Factory direct sales, No middlemen make a difference.

  • 【Customization Service】

Product specifications can be customized to create your own peptide brand.

  • 【Quality Guarantee】

Professional lab reports along with shipment.

  • 【Fast Shipping】

Professional logistics customization solutions, on-time delivery.

  • 【Easy Payment】

Payment methods that are diverse.

  • 【365/24/7 Service】

High quality pre-sales and after-sales service, followed by product and order details consultation.

How To Get The Quick Price Of Ipamorelin Online?

  • Visit professional Ipamorelin supplier Phcoker.com, choose the Ipamorelin you want to buy.
  • Leave your contact and message on Phcokerwebsite, then submit to Phcoker.com.
  • The customer service will reply you in 12 hours once received your message, then talk in details about buy Ipamorelin.

Does Phcoker.com Support The Free Sample Of Ipamorelin Powder?

It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for sample.

Can I Appoint The Ipamorelin Colour When Buy Ipamorelin?

YES! Phcoker as peptide manufacturer, provide colour customization of Ipamorelin, easy to help you to build your Ipamorelin peptide brand.

Can I Appoint The Products Standard When Buy Ipamorelin From Phcoker.com?

YES! As one of the best Ipamorelin manufacturer, Phcoker not only provide the standard specification of Ipamorelin in 5mg, 10mg, but support standard customization. Provide the best support to build your own Ipamorelin brand.

Can I Buy Ipamorelin In Pure Powder Form From Phcoker.com?

YES! Ipamorelin powder is the base that use for Ipamorelin lyophilized powder manufacture. Phcoker provide Ipamorelin in both of pure powder form and semi-finished vial form.

Can I Buy Discount Ipamorelin Powder From Phcoker.com?

YES! Our factory produce high quality Ipamorelin powder in term and keep Ipamorelin powder in stock. You can buy high quality Ipamorelin powder in bulk. During promotion sale, you can buy Ipamorelin peptide by lower price. You can keep touch with our customer manager and they will update the latest bulk Ipamorelin price for you in time.

 

FAQ


What does Ipamorelin do?

Ipamorelin is a growth hormone-releasing peptide that can stimulate the release of growth hormone. It can relieve pain and regulate body growth, thyroid function and body temperature.

Can Ipamorelin promote fat burning?

Ipamorelin is a very effective ghrelin on the market that reduces body fat and increases muscle mass and strength.

What is the dosage of Ipamorelin?

According to research, although some treatment plans recommend a maximum dose of as high as 500 micrograms, the lowest dose should be started at 200 micrograms.

Does Ipamorelin have any effect on increasing testosterone levels?

GH stimulates the pituitary gland to produce luteinizing hormone (LH), and LH stimulates the testicles to produce testosterone, so Ipamorelin will increase testosterone levels.

How quickly does Ipamorelin take effect?

According to research results, most patients can see physical changes after one month, and it takes about 3-6 months to fully experience the benefits of Ipamorelin.

Is Ipamorelin safe?

Ipamorelin is well tolerated and generally considered safe for long-term use. However, each user reacts differently to medications, and you should consult with your healthcare provider before using this medication.

Is Ipamorelin effective against aging?

Ipamorelin can increase the level of growth hormone in the blood, which not only reduces appetite and improves sleep quality, but also promotes collagen production, tightens skin, and repairs wrinkles.

Does Ipamorelin affect blood sugar?

There is scientific evidence that GH secretion can be promoted through injection of ghrelin. GH secretion can improve blood sugar levels in diabetic patients, while Ipamorelin can increase GH levels.

Does Ipamorelin enhance cortisol?

Cortisol increases the body’s blood pressure and heart rate, but unlike other analogues, Ipamorelin does not increase cortisol levels in the body.

Can Ipamorelin promote hair growth?

Treatment with GH will increase the level of growth hormone in the human body, thereby making hair thicker and shinier.

Will Ipamorelin improve sleep quality?

Ipamorelin may improve sleep quality through an increase in growth hormone, thereby promoting better sleep.

Referenced Citations


[1]Nets’ Chandler suspended 25 games for PED use. nba.com. Retrieved 2019-08-30.

[2]Maloney J (13 April 2018). NBA Playoffs 2018: Wizards’ Jodie Meeks suspended 25 games for failing drug test. CBSSports.com. Retrieved 2018-04-14.

[3]Perez AJ (5 May 2016). Peptides under greater scrutiny in MLB’s performance-enhancing drug battle. USA TODAY. Retrieved 2018-04-14.

[4] Ipamorelin. AdisInsight. Springer Nature Switzerland AG. Retrieved 10 June 2015.

[5] Jiménez-Reina L, Cañete R, De la Torre MJ, Bernal G (2002). Chronic In Vivo Ipamorelin Treatment Stimulates Body Weight Gain and Growth Hormone (GH) Release In Vitro in Young Female Rats. European Journal of Anatomy. 6 (1): 37–46. ISSN 1136-4890.

[6]Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.Doi N, Hirotani C, Ukai K, Shimada O, Okuno T, Kurasaki S, Kiyofuji T, Ikegami R, Futamata M, Nakagawa T, Ase K, Chihara K.

[7]J Endocrinol. 1991 Apr;129(1):11-9. doi: 10.1677/joe.0.1290011.PMID: 1674284.Desensitization studies using perifused rat pituitary cells show that growth hormone releasing hormone and His D Trp Ala Trp D Phe Lys NH2 stimulate growth hormone release through distinct receptor sites.

[8] Gobburu JV, Agersø H, Jusko WJ, Ynddal L (September 1999). Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharmaceutical Research. 16 (9): 1412–6. doi:10.1023/A:1018955126402. PMID 10496658. S2CID 12048934.

[9]Moulin A, Ryan J, Martinez J, Fehrentz JA (September 2007). Recent developments in ghrelin receptor ligands. ChemMedChem. 2 (9): 1242–59. doi:10.1002/cmdc.200700015. PMID 17520591. S2CID 24945528.

[10]Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH (November 1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. 139 (5): 552–61. doi:10.1530/eje.0.1390552. PMID 9849822.

[11] Isidro ML, Cordido F (March 2006). Growth hormone secretagogues. Combinatorial Chemistry & High Throughput Screening. 9 (3): 175–80. doi:10.2174/138620706776055458. PMID 16533150

[12]Effects of growth hormone on body fat in adults. Gertner JM.

[13]Psychological functioning after growth hormone therapy in adult growth hormone deficient patients:endocrine and body composition correlates. Lasaite L.

[14]Lee D,Lee SH,Cho N,Kim YS,Song J,Kim H.Int J Mol Sci. 2019 Mar 12;20(5):1253. doi:10.3390/ijms20051253.PMID: 30871109.Effects of Eleutherococcus Extract Mixture on Endochondral Bone Formation in Rats.

[15]Howick K,Griffin BT,Cryan JF,Schellekens H.From Belly to Brain:Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation.Int J Mol Sci.2017 Jan27;18(2):273.doi:10.3390/ijms18020273.PMID: 28134808

 

Author of this article:


Dr. Jean Zeng graduated from king’s college london Faculty of Life Sciences & Medicine.

 

Scientific Journal paper Author:


1.Enrico Gerace

Dipartimento di Chimica, Università degli Studi di Torino, Turin, Italy

2.Bernd Peschke

Discovery Chemistry, Novo Nordisk A/S, Novo Nordisk Park, 2760 Måløv, Denmark

3.N.B. Andersen

Department of Connective Tissue Biology, Institute of Anatomy, University of Aarhus, Aarhus C, DK-8000, Denmark

4.Peter B. Johansen

Department of Pharmacological Research, Novo Nordisk A/S, Bagsværd, DK-2880, Denmark

5.Thomas K. Hansen

Novo Nordisk, Novo Nordisk Park, 2760 Måløv, Denmark


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