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Conjugated linoleic acids (CLA) 95% (121250-47-3)

Conjugated Linoleic Acid, or CLA, is a term used to refer to a mixture of fatty acids that have the general structure of………

 


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

 

Description

Conjugated linoleic acids (CLA) Specifications

Product Name Conjugated linoleic acids (CLA) 95%
Chemical Name 9,11-Linoleic acid;9,11-Octadecadienoic acid;Conjugated Linolenic Acid,CLA;CIS-10,CIS-12-OCTADECADIENOICACID;CIS-10-CIS-12-CONJUGATEDLINOLEICACID;TRANS-10,TRANS-12-OCTADECADIENOICACID;Conjugated linoleic acid – Microencapsulated solid;Octadecadienoic Acid (Conjugic Acidd, cis-9,Trtans-11) (C18:2)
Brand Name N/A
Drug Class N/A
CAS Number 121250-47-3
InChIKey OYHQOLUKZRVURQ-HZJYTTRNSA-N
Molecular Formula C18H32O2
Molecular Weight 280.44
Monoisotopic Mass 280.24023 g/mol
Boiling point  444 to 446 °F at 16 mm Hg (NTP, 1992)
Freezing Point N/A
Biological Half-Life Easily oxidized by air.
Color Yellow liquid
Solubility  Freely soluble in ether; soluble in absolute alcohol; 1 mL dissolves in 10 mL petroleum ether; miscible with dimethylformamide, fat solvents, oils
Storage Temperature  Store at -20° C
Application A family of 8 geometric isomers of linoleic acid

 

What is Conjugated linoleic acids (CLA)?

Conjugated Linoleic Acid, or CLA, is a term used to refer to a mixture of fatty acids that have the general structure of linoleic acid (18 carbons in length, 2 double bonds) where the double bonds exist two carbons away from each other; they are all polyunsaturated fatty acids, and some may be trans fatty acids.

Our Conjugated Linoleic Acid (CLA) is produce by the technology of Supercritical fluid extraction. CLA is marketed as a dietary supplement on the basis of its supposed health benefits. It is a popular dietary supplement that is sold with claims of helping people lose fat, maintain weight loss, retain lean muscle mass, and control type 2 diabetes — the type of diabetes that is often associated with obesity. CLA has been shown to offer numerous health benefits with respect to cardiovascular disease, cancer, obesity, osteoporosis and the immune system.

Others believe that CLA can enhance immune function while improving high cholesterol and blood pressure levels. Despite its popularity among some athletes, the evidence remains split on whether CLA can deliver on these promises.

Conjugated linoleic acids (CLA) benefits

CLA is a naturally occurring fatty acid found in certain animals and animal food products, like ground beef and other meats, cheese and dairy—types of food often excluded in diet plans. Because the human body can’t produce CLA, we can only get it through our diet or supplements in order to reap the benefits.

CLA can lower blood lipids, soften blood vessels, lower blood pressure, and promote microcirculation, can prevent or reduce the incidence of cardiovascular disease, especially for high blood pressure, high cholesterol, angina, coronary heart disease, atherosclerosis, and senile obesity prevention and control of extremely strong, can prevent human serum cholesterol in the blood vessel walls deposits, have “vascular scavenger” reputation, the prevention and treatment of atherosclerosis and cardiovascular disease with health effects.

Health Benefits

  1. Helps with Weight Loss and Fat-Burning
  2. Regulates Blood Sugar and Helps Improve Insulin Function
  3. Improves Immune Function and Might Help Fight Cancer
  4. Reduces Allergies and Asthma Symptoms
  5. Improves Rheumatoid Arthritis Symptoms
  6. Might Improve Muscle Strength
  7. Reversing atherosclerosis (hardening of the arteries)
  8. Improving digestionreducing food allergies and sensitivities
  9. helping to normalize blood sugar levels

Conjugated linoleic acids (CLA) dosage

The FDA allows CLA to be added to foods and gives it a GRAS (generally regarded as safe) status.

Most studies on CLA have used doses of 3–6 grams per day. Doses greater than 6 grams may increase the risk of side effects.

 

Conjugated linoleic acids (CLA) possible side effects.

Conjugated linoleic acids (CLA) has been granted “Generally Recognized As Safe” status in the U.S. for use as a dietary supplement. It is considered safe to use CLA if taken as prescribed, some people may experience side effects, usually mild, including stomach upset, diarrhea, nausea, fatigue, headache, and backache.

CLA is mainly metabolized in the liver. On rare occasion, CLA may cause liver toxicity (usually in people with underlying liver disease). Large doses can also trigger the accumulation of fat in the liver, leading to fatty liver disease, diabetes, and metabolic syndrome.

Conjugated linoleic acid may also slow blood clotting. Taking a CLA supplement along with an anticoagulant (“blood thinners”) or nonsteroidal anti-inflammatory drug (NSAID) can further enhance this effecting, leading to easy bruising and bleeding.

 

Conjugated linoleic acids (CLA) uses and application.

Applied in food and beverage ingredients;

Applied in cosmetics additives;

Acid Applied in health products;

Applied in nutrition supplement;

Applied in pharmaceutical industry;

Applied in weight loss.

 

Reference:

  • R.C. Khanal, T.R. Dhiman Biosynthesis of conjugated linoleic acid (CLA): a review Pak. J. Nutr., 3 (2004), pp. 72-81
  • Conjugated linoleic acid metabolism Curr. Opin. Lipidol., 13 (2002), pp. 261-266
  • K.W. Lee, H.J. Lee, H.Y. Cho, Y.J. Kim Role of the conjugated linoleic acid in the prevention of cancer Crit. Rev. Food Sci. Nutr., 45 (2005), pp. 135-144
  • Tang, K.V. Honn 12(S)-HETE in cancer metastasis Adv. Exp. Med. Biol., 447 (1999), pp. 181-191 Churruca I et al. Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors 2009;35(1):105-11.

 

PRECAUTION AND DISCLAIMER:

This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

 


Video

Conjugated linoleic acids (CLA) 95% (121250-47-3) video

References & product citations

 

Reference:

  • R.C. Khanal, T.R. Dhiman Biosynthesis of conjugated linoleic acid (CLA): a review Pak. J. Nutr., 3 (2004), pp. 72-81
  • Conjugated linoleic acid metabolism Curr. Opin. Lipidol., 13 (2002), pp. 261-266
  • K.W. Lee, H.J. Lee, H.Y. Cho, Y.J. Kim Role of the conjugated linoleic acid in the prevention of cancer Crit. Rev. Food Sci. Nutr., 45 (2005), pp. 135-144
  • Tang, K.V. Honn 12(S)-HETE in cancer metastasis Adv. Exp. Med. Biol., 447 (1999), pp. 181-191 Churruca I et al. Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors 2009;35(1):105-11.