+86(1812)4514114 [email protected]

Galantamine Hydrobromide (69353-21-5)

Galantamine hydrobromide is a benzazepine derived from…….


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1290kg/month

Description

Galantamine Hydrobromide (69353-21-5) video

 

Galantamine Hydrobromide (69353-21-5) Description

Galantamine hydrobromide is a benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.

Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer’ s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.

Galantamine Hydrobromide (69353-21-5) Specifications

Product Name Galantamine Hydrobromide
Chemical Name Galantamin; Galantamine; Galanthamine
Galanthamine Hydrobromide; Lycoremine; Nivalin
Nivaline; Razadyne; Reminyl
Galanthamine hydrobromide; Galantamine hydrobromide; 1953-04-4; Reminyl; Galanthamine (hydrobromide);
Brand Name No data available
Drug Class Alzheimer Disease Agents, cholinesterase inhibitor
CAS Number 69353-21-5
InChIKey QORVDGQLPPAFRS-XPSHAMGMSA-N
Molecular Formula C17H22BrNO3
Molecular Weight 368.271 g/mol
Monoisotopic Mass 367.078 g/mol
Melting Point  126-127 deg C
Freezing Point No data available
Biological Half-Life Elimination half-life: 7 hours
Color White solid
Solubility  Fairly soluble in hot water; freely soluble in alcohol, acetone, chloroform. Less sol in benzene, ether.
Storage Temperature  −20°C
Application cholinesterase inhibitor; medicine

 


=

Reviews

There are no reviews yet.

Be the first to review “Galantamine Hydrobromide (69353-21-5)”

Your email address will not be published. Required fields are marked *

Shangke Chemical is a high-tech enterprise specializing in active pharmaceutical intermediates (APIs). To control the quality during production, a large number of experienced professionals, a first-class production equipment and laboratories are the key points.

Contact Us