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Triptorelin (57773-63-4)

Triptorelin is a gonadotropin-releasing hormone (GnRH) agonist and a potent inhibitor of testosterone (male) and estrogen ………


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1277kg/month

Description

Triptorelin (57773-63-4) video

 

Triptorelin (57773-63-4) Description

Triptorelin is a gonadotropin-releasing hormone (GnRH) agonist and a potent inhibitor of testosterone (male) and estrogen (female) synthesis for the treatment of advanced prostate cancer. Triptorelin was associated with a transient increase in serum enzymes during treatment, but was not convincingly linked to clinically significant cases of acute liver injury.

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Triptorelin has greater potency than endogenous LHRH and reversibly inhibits gonadotropin secretion. After chronic continuous administration, the drug can continue to reduce LH and FSH production as well as testicular and ovarian steroid production. Serum testosterone concentrations may be reduced to levels normally observed in men who have undergone surgical castration.

Triptorelin (57773-63-4) Specifications

Product Name Triptorelin
Chemical Name TRIPTORELIN; 57773-63-4; Triptoreline; Triptorelina; Triptorelinum; Decapeptyl
Brand Name Trelstar Depot
Drug Class Peptide
CAS Number 57773-63-4
InChIKey VXKHXGOKWPXYNA-PGBVPBMZSA-N
Molecular Formula C64H82N18O13
Molecular Weight 1311.473 g/mol
Monoisotopic Mass 1310.631 g/mol
Melting Point  >180°C
Freezing Point no data available
Biological Half-Life  after a 3 to 4 hr
Color White powder
Solubility  Soluble in water
Storage Temperature  -20°C
Application A GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation

 


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