Resveratrol Powder (501-36-0) Specifications
| Product Name | Resveratrol |
| Chemical Name | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol |
| Synonyms | trans-resveratrol;
3,4′,5-Trihydroxystilbene; 3,5,4′-Trihydroxystilbene (E)-5-(4-Hydroxystyryl)benzene-1,3-diol; 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol; |
| CAS Number | 501-36-0 |
| InChIKey | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 |
| Monoisotopic Mass | 228.078644241 |
| Melting point | 253-255°C |
| Boiling point | 449.1±14.0 °C(Predicted) |
| Color | Off-white |
| Density | 1.359±0.06 g/cm3(Predicted) |
| Form | Powder |
| Water Solubility | Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL). |
| Storage Temperature | Store at -20° C |
| Application | Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. |
| Assay | ＞98% |
| Testing Document | Available |
Resveratrol is one of the most widely known antioxidant compounds in the supplement industry. It has been known to celebrities, athletes and other public figures over the years. Research suggests this powerful antioxidant has many health benefits as well as positive effects on the skin. Many people take resveratrol for its anti-inflammatory, anti-aging, weight loss and blood sugar control properties.
With so many resveratrol supplements on the market today, it can be difficult to decide which product is right for you. Therefore, you should have a full understanding and awareness of resveratrol before purchasing.
What Is Resveratrol Powder?
Resveratrol(3,5,4′-trihydroxy-trans-stilbene) is a class of plant micronutrients called polyphenols and a naturally occurring potent antioxidant. It is produced by several plants in response to damage and has many powerful health benefits.
In fact, resveratrol is naturally present in many foods in our daily diet. You can easily find it in foods like red grape skins, mulberries, peanuts, knotweed, berries, and tea. Among them, Japanese knotweed is the plant source with the highest content of resveratrol.
Resveratrol exerts a variety of biological activities, including anti-inflammatory, anti-proliferative, and antioxidant effects. It can protects you from diseases like cancer, diabetes and Alzheimer’s disease. Its anti-inflammatory properties make it a great treatment for arthritis and skin inflammation. In addition to this, resveratrol also has antibacterial and antifungal properties that help treat urinary and digestive tract infections.
As the research into resveratrol has deepened, health experts have begun to recognize the true benefits of resveratrol. And resveratrol powder was found to help lower blood pressure and protect brain function.
Resveratrol vs Trans-Resveratrol
Did you spot a mention of “trans-resveratrol” too? You might wonder if they are the same.
Resveratrol(501-36-0) is the generic product name used in supplements. But actually, resveratrol comes in two different forms: cis-resveratrol and trans-resveratrol. Of these, trans-resveratrol is more commonly found in plants. It is a more bioactive natural chemical and the type of resveratrol found in most daily nutritional supplements. Regular resveratrol (also known as cis-resveratrol) is still biologically active and still has antioxidant properties, although it doesn’t seem to have as many benefits as trans-resveratrol.
The difference between the two types comes down to how easily your body absorbs and uses it. Here is the breakdown:
￭ Red grape skins are rich in resveratrol. However, the health benefits only occur when the body is converted to trans-resveratrol.
￭Trans-resveratrol is a chemical form of resveratrol that can be absorbed and used by the body. For example, Japanese knotweed contains high concentrations of trans-resveratrol. This pure bulk resveratrol powder from Knotweed is standardized to contain at least 98% trans-resveratrol. This makes it an effective source of supplements.
What Forms Are Resveratrol Supplements Available On The Market?
In the past two years, with the hype of red wine advertisements for its beauty and beauty benefits, people have gradually recognized a powerful antioxidant ingredient resveratrol. Not only is it a nutrient found naturally in our food that helps us fight aging, it also has anti-inflammatory properties and maintains a healthy brain and heart. As people continue to understand the benefits of resveratrol, the demand for resveratrol in the market is also rising, and it was once one of the most popular products in the supplement market. At the same time, many resveratrol suppliers and manufacturers began to sell resveratrol in bulk online and offline, mainly in powder, capsule, pill and liquid form.
–Dietary Supplements: Resveratrol can be used as dietary supplements such as red wine extract, grape seed extract and Japanese knotweed extract. Most supplements on the market come from Japanese knotweed, as this plant has one of the highest concentrations of resveratrol found in nature.
The amount and purity of resveratrol in supplements varies widely. Micronized resveratrol is available in pill or powder form. Because of the low systemic bioavailability of resveratrol, oral absorption is poor. The resveratrol powder supplied by Phcoker manufacturer factory undergoes a micronization process that greatly reduces the average particle size of the compound and increases absorption.
–Skincare: Due to its powerful antioxidant properties, resveratrol is also commonly used in various skincare products for anti-aging and maintaining youthful skin. Such as serums, creams and moisturizers.
In addition, resveratrol is also available in solution form and in transdermal patches. Although its safety and efficacy have not been approved by the U.S. Food and Drug Administration, resveratrol is generally considered a healthy dietary supplement.
How Does Resveratrol Work?
Resveratrol can be found in the skins and seeds of grapes and in peanuts. It has demonstrated potent antioxidant, anti-inflammatory, and anti-proliferative activities. Topical application of resveratrol in mice demonstrated photoprotection by significantly decreasing UVB-mediated generation of hydrogen peroxide and infiltration of leukocytes. Its antiproliferative properties are related to the inhibition of cellular events associated with tumor initiation, promotion, and progression, and the triggering of apoptosis in tumor cells.
Why Is Resveratrol Powder Important?
Resveratrol is a phytoalexin, which means it is a protective antibiotic produced when plants are stressed, whether due to fungal attack, drought, UV exposure or inflammation. This molecule helps plants fight back and stay healthy. Scientists have become interested in resveratrol due to its antioxidant properties, which are thought to potentially confer longevity, anti-inflammatory, heart-healthy, and anti-cancer properties through a variety of mechanisms.
Like other antioxidants, resveratrol allows the body to effectively detoxify molecules that oxidize other molecules and tissues. The body is protected from these dangerous molecules by capturing and breaking them down, thereby removing them from the cellular environment. In addition to its own antioxidant properties, antioxidants can also oxidize themselves by free radicals and then regenerate. This protects other key molecules and cells from oxidative damage.
Healthy levels of antioxidants help repair damage caused by oxidants and are essential for preventing chronic inflammatory damage, stopping precancerous changes and slowing changes in aging. So, when your body is deficient in resveratrol, the ability to fight harmful molecules and antioxidants will also decrease, which may affect the body. Properly supplementing resveratrol powder to keep it in a healthy state is beneficial to our health.
What Are the Benefits of Resveratrol Supplements?
As research into resveratrol benefits has grown, it has been touted as having many body health benefits, such as protecting the heart and circulatory system, lowering cholesterol, and preventing blood clots that can lead to heart attacks and strokes.
1.Resveratrol for brain and heart health
(1)For brain
Some studies suggest that resveratrol may have an effect on cognitive decline. A protein fragment of beta-amyloid is essential for the formation of plaques that are a hallmark of Alzheimer’s disease. As a potent antioxidant and anti-inflammatory compound, resveratrol affects the cells in your body by protecting them from damage. It appears to interfere with this segment to slow age-related cognitive decline.
(2)For heart health
In addition, there are studies showing that resveratrol can effectively reduce the risk of heart disease. In high doses, it can lower blood pressure by reducing the pressure on the walls of blood vessels as the blood pumps. It can also have a positive effect on blood lipids, lowering cholesterol by reducing the effects of enzymes that control cholesterol production.
Most notably, it helps with brain and heart inflammation by providing a protective lining for your blood vessels and preventing insult or injury. This means it could have neuroprotective qualities and help preserve memory and brain function, as well as prevent heart disease and strokes.
2.Resveratrol for aging
(1)For skin
Oxidative stress is one of the main causes of skin aging. As an antioxidant, resveratrol is great for reducing this effect. One of its most valuable features is its ability to stimulate the production of other antioxidants that provide further protection to the skin.
–Protects the skin: Our skin is the largest organ in the human body, and it is your body’s first line of defense against harmful microorganisms. Resveratrol interrupts negative environmental influences and protects the skin from UV rays. Using antioxidants like resveratrol can help strengthen your skin’s natural barrier, making your skin look and feel smoother and healthier.
–Anti-aging: Resveratrol works at the cellular level to fight the aging process by stimulating healthy cellular proliferation.
–Reduces Redness: Resveratrol contains key skin calming properties that help minimize the appearance of redness and inflammation.
Evens skin tone: Not only does resveratrol brighten and even improve skin tone, it also improves the overall texture of the skin.
–Moisturizes the skin: Resveratrol hydrates your skin and prevents it from drying out.
In addition to the aforementioned benefits, resveratrol also has phytoestrogenic properties that can help stop collagen and skin elasticity from declining with age. It also inhibits tyrosinase, an important enzyme in melanin biosynthesis, which helps smooth irregular hyperpigmentation in the skin for fresher, younger-looking skin.
(2)For lengthens lifespan
The resveratrol’s ability to extend lifespan in different organisms has become a major area of research. There is evidence that resveratrol can activate certain genes to ward off diseases of aging.
The study found that resveratrol extended the lifespan of study organisms by 60 percent, but the effects were strongest in organisms less related to humans, such as worms and fish.
It does this in the same way as calorie restriction, by altering the way genes express themselves, and has shown promise in extending lifespan.
3.Resveratrol for cancer
Resveratrol has the benefits to prevent and treat cancer. In animal and test-tube studies, it has been shown to fight several types of cancer cells, including gastric, colon, skin, breast, and prostate cancers, among others.
Resveratrol may prevent cancer cells from replicating and spreading by altering gene expression in cancer cells to inhibit their growth. It may also interfere with the way certain hormones are expressed, thereby preventing the spread of hormone-dependent cancers.
However, because the studies to date have been conducted in test tubes and animals, more research is needed to understand if and how this compound could be used in human cancer treatment.
4.Other benefits
Besides, resveratrol also have some potentital benefits:
– Support for cardiovascular health
– assists with increasing HDL and reducing LDL cholesterol
– Helps reduce blood clotting
– May help lower blood pressure, hypoglycemic and blood fats.
– May Increase Insulin Sensitivity
– May Ease Joint Pain
– Relieve poor pulmonary function
– Protect ovarian health
– Relieve Testicular malfunction and male infertility
– Help treat obesity
– Antiplatelet
– Prevention of osteoporosis
However, more research is needed to determine the benefits of resveratrol. Unfortunately, research on human subjects is limited. On the positive side, researchers are working hard to examine its positive effects.
How Can We Get Resveratrol?
As we know, grape skins produce large amounts of resveratrol, which protects plants from fungal diseases and sun damage; therefore, red wine has higher levels of resveratrol than other natural foods. Drinking wine to get more resveratrol is a good option. But drinking can cause a lot of bad effects, so drinking a lot of red wine to get more resveratrol is not a long-term good idea.
But this is not a problem. Research has found that resveratrol is a naturally occurring micronutrient found in more than 70 plants, many of which are part of our daily diet. So, in addition to getting resveratrol from red wine, we can also get the resveratrol our body needs in the form of food and resveratrol powder supplements.
What Foods Are High In Resveratrol?
Resveratrol powder supplements are a convenient way to get a full dose of resveratrol. However, considering that foods high in the polyphenol resveratrol are plant-based, it is easy to find it in our daily diet. Such as:
– Peanuts
– Pistachios
– Grapes
– Red Wine
– Blueberries
– Cranberries
– Bilberries
– Berries
– Cocoa and Dark Chocolate
There are many more resveratrol-rich foods in life, and the above are just a few of them. If you want to learn more about the source of resveratrol, you can look it up online, consult the resveratrol raw material manufacturer Phcoker and a health professional.
How Much Resveratrol Powder Should l Take Daily?
Currently, there is no “safe” effective dose of resveratrol powder. Still, experts recommend a standard adult dose of 150 mg per day, or more, depending on individual needs. Always consult a trusted healthcare professional for expert advice before self-medicating. Also, always read and follow the dosing instructions that come with your supplement.
Possible side effects of Resveratrol
According to research, small doses of resveratrol do not cause serious side effects. However, at long-term doses above 2.5 grams, studies have found problems such as nausea, vomiting and diarrhea. Some studies suggest that people with nonalcoholic fatty liver disease may experience liver problems, and high doses may be associated with high fever and decreased blood pressure. Also, if you take blood-thinning pills such as warfarin, aspirin, or ibuprofen, you also may increase your risk of excessive bleeding.
While no other potential side effects of resveratrol have been identified, make sure to do your due diligence before trying new ingredients or actively increasing your intake. Avoid causing health problems or adverse reactions. If you are taking certain medications for health maintenance or are prone to allergic reactions, please consult your doctor, resveratrol raw powder supplier or healthcare provider beforehand.
Last but not less, use resveratrol with caution when:
▲People with bleeding disorders may find that resveratrol slows blood clotting and increases the risk of bleeding. Patients should be monitored by a physician while taking this product. People undergoing surgery should stop taking resveratrol two weeks before surgery and two weeks after surgery.
▲Resveratrol has mild estrogenic activity, until more is known, with cancer and other estrogen-sensitive diseases (breast, uterine, ovarian, endometriosis or uterine fibroids) of women should seek medical advice before taking resveratrol.
▲Do not take resveratrol supplements or excessive amounts of resveratrol-containing natural foods during pregnancy or breastfeeding. There is a lack of research in this area to demonstrate safety. Children should avoid resveratrol.
▲Resveratrol reduces the activity of enzymes involved in drug metabolism, but whether it has significant effects in humans has not been studied.
What Other Drugs Will Affect Resveratrol?
1.Resveratrol supplement interaction
As with all supplements, other medications may interact with resveratrol while taking it. If you take any medications or other supplements on a regular basis, consult your manufacturer/healthcare provider before starting a resveratrol supplement powder. They can be combined with blood thinners, blood pressure medications, cancer treatments, blood pressure medications, anti-anxiety medications, immunosuppressants, MAOI antidepressants, antiviral and antifungal medications, non-steroidal anti-inflammatory drugs as well as St. John’s wort, garlic and Ginkgo biloba and other supplements interact.
2.Resveratrol supplement synergy
(1) Resveratrol and quercetin
Resveratrol and quercetin are plant polyphenols that xhibit anti-inflammatory properties and anti-insulin resistance when administered in isolation or combination. Recently, we also found that grape powder extract containing resveratrol and quercetin reduced inflammatory markers in human adipocytes and macrophages and insulin resistance in human adipocytes. Meantimes, a mixture of resveratrol and quercetin that may affect fatty liver in individuals with metabolic syndrome.
(2)Resveratrol and curcumin
The synergistic effect of curcumin and resveratrol has been found to inhibit colon cancer, suggesting that resveratrol also has anticancer properties and acts as a stabilizer for curcumin.
(3)Resveratrol and melatonin
The combination of resveratrol and melatonin reduced tumour incidence by approximately 17% and significantly decreased the quantity of invasive and in-situ carcinomas.
FAQ
(1)What is resveratrol?
Resveratrol is a polyphenolic antioxidant found in red wine, the skin of red grapes, certain berries, and peanuts. Resveratrol has several beneficial properties, such as promoting bone health, supporting weight loss, supporting heart health, and potentially enhancing longevity.
(2)What is the best source of resveratrol?
Resveratrol is found in many foods and plants. It’s usually found in grape skins, dark chocolate, berries, pistachios, peanuts, red and white wine, and even cocoa. However, the problem here is that these foods don’t have a lot of resveratrol, and you need to consume a lot to reap any benefits. That’s why supplements are most people’s go-to, especially those that use resveratrol extracted from Japanese knotweed.
How do I take resveratrol?
Some people take resveratrol in supplement form. You can find resveratrol supplements in capsules or powders. Others supplement resveratrol by taking berries, grapes, wine, blueberries, cranberries, pomegranate, or fruit juice daily.
(3)Why is red wine good for health?
Some studies suggest that red wine supports health because it contains doses of resveratrol.
(4)Does resveratrol help cancer?
Several small studies have shown that resveratrol can kill cancer cells or help treat cancer in other ways. However, we need more studies, especially large-scale studies in humans, to verify these effects.
(5)Does resveratrol help lower blood pressure?
Research shows that resveratrol can help lower blood pressure by raising nitric oxide levels, relaxing blood vessel walls, and supporting other aspects of cardiovascular health.
(6)Does resveratrol help lower cholesterol?
Research shows that resveratrol can neutralize bad cholesterol while promoting good cholesterol, which can make it an effective supplement for people with high cholesterol.
(7)Does resveratrol help with dementia and Alzheimer’s disease?
Research suggests that resveratrol may help treat dementia and Alzheimer’s disease by targeting plaques that build up inside blood vessels in the brain. Some studies suggest that taking a daily resveratrol supplement can slow the progression of the disease.
(8)Can resveratrol reverse aging?
Resveratrol may contribute to brain ageing reversal by as much as ten years: Study. A long-term study adds to the science backing resveratrol’s benefits as it finds the regular consumption of this plant compound could slow cognitive decline by as much as a decade.
(9)Is resveratrol better than vitamin C?
It’s such a powerful antioxidant that it works even better than vitamin E and vitamin C when it comes to fighting off existing free radicals and preventing the formation of new free radicals.
(10)Does resveratrol work for weight loss?
Overall, the current meta-analysis demonstrated that resveratrol intake significantly reduced weight, BMI, WC and fat mass, and significantly increased lean mass, but did not affect leptin and adiponectin levels.
(11)Is resveratrol anti-inflammatory?
Taken together, these studies suggest that resveratrol can prevent inflammation and oxidative stress, reduce the risk of carcinogenesis and developed as anti-inflammatory agent to improve the quality of life of patients.
(12)Is resveratrol good for the brain?
Resveratrol, a plant-based compound found in red grapes and peanuts, exerts beneficial effects on the human brain. Clinical trials have demonstrated that resveratrol reduces levels of amyloid-beta in cerebrospinal fluid and improves cognitive function in people with Alzheimer’s disease.
(13)How much resveratrol is in a glass of red wine?
Red wines have a resveratrol content (per 5-oz glass) of 0.03-1.07 milligrams (mg), which is comparable to the resveratrol content in white wines, which is typically in the range of 0.01-0.27 mg. Red grape juice contains 0.017-1.30 mg per 5 oz.
(14)Is resveratrol good for your liver?
It provided liver protection against chemical, cholestatic, and alcohol injury. Resveratrol can improve glucose metabolism and lipid profile and decrease liver fibrosis and steatosis. Furthermore, it was able to alter hepatic cell fatty acid composition.
(15)What is the best time of day to take resveratrol?
They found that a young person, for example, should take NMN six hours after they wake up to achieve the highest efficiency. On the other hand, young individuals should take Resveratrol at night while older people should take it midday for the greatest effectiveness.
(16)How much resveratrol do I put in Covid?
Resveratrol group (treatment group) will be instructed to consume with capsules (1.0 g, orally once a day) for six months. Resveratrol has been used as a food supplement. Its antiviral properties have been well studied including its inhibitory effect against the coronavirus MERS-CoV.
(17)What is the best resveratrol supplement to take?
The best resveratrol supplement for you is the one that addresses your needs. As always, we urge you to consult a doctor before taking a supplement. First, a doctor will determine whether your needs and wants should be met with the help of a resveratrol supplement. Second, a medical specialist will help pick a dosage that will be safe yet beneficial.
(18)Can I use resveratrol with other active ingredients like retinol, AHA/BHA or vitamin C?
In general, resveratrol works with, and actually works well with, active ingredients, especially antioxidant-rich ones like vitamin C.
(19)Does resveratrol help treat acne?
Research shows that resveratrol actually inhibits the growth of acne-causing bacteria. When it’s combined with benzoyl peroxide, it helps boost antibacterial properties.
Where is Resveratrol Bulk Powder Sold?
Resveratrol powder wholesale trades are much more common than retail sales as it is usually purchased in bulk directly from the resveratrol powder manufacturer factory. For resveratrol tablet/capsule suppliers or raw powders resellers who need to buy resveratrol powder in bulk, they can find a reputable company online or offline, and buy the best quality resveratrol acid raw materials at the best price.
Resveratrol Powder Summary
From reading the above articles, we learned that resveratrol is associated with many health benefits. Naturally occurring resveratrol is very safe. Taking resveratrol supplement powder daily may help with weight loss, prevent cardiovascular disease, and improve brain health, and it may even have anticancer, antiviral properties, and many other benefits.
However, there are so many resveratrol suppliers out in market, and while they all claim to offer the best resveratrol, not all resveratrol supplements are created equal. That’s why it’s critical to double-check everything from brand reputation to substances used in products before buying. After you do the proper research and find a raw supplement that’s right for you, there’s nothing stopping you from getting the resveratrol dose you need.
More About Resveratrol
Resveratrol has antiviral, antioxidant and anti-inflammatory properties. It has been studied and shown to be effective against a variety of different viruses, including in the treatment of viruses such as influenza, hepatitis C virus, respiratory syncytial virus, human immunodeficiency virus (HIV), enteroviruses and human metapneumonia virus. The study found that resveratrol showed high antiviral potential, and eliminates inflammation and reduces free radical damage to the lungs.
At present, the new coronavirus(covid) epidemic is not over yet, and the issue of whether resveratrol is equally effective against the virus still requires continuous research and exploration by researchers.
Reference
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