Endurobol (317318-70-0) video
Endurobol (317318-70-0) Description
Endurobol is a PPARδ receptor. It activates the same pathways activated through exercise, including PPARδ and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. Endurobol has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound alone.
Endurobol could be used by athletes as an ergogenic performance enhancing drug that was not currently controlled by regulations or detected by standard tests. One of the main researchers from the study on enhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee.
Endurobol (317318-70-0) Specifications
|Chemical Name||2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid;GW-501615;CB6465728;2-(4-((2-(4-(Trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic a;GW1516; GSK-516.|
|Drug Class||Inhibitors;Intermediates & Fine Chemicals; Pharmaceuticals;Sulfur & Selenium Compounds;kl; Inhibitor;Antineoplastic;SARMs(Selective androgen receptor modulator);Sarms|
|Molecular Weight||453.494 g/mol|
|Monoisotopic Mass||453.068 g/mol|
|Boiling Point||584.543ºc at 760mmhg|
|Biological Half-Life||16-24 hours|
|Color||white to beige|
|Solubility||DMSO: soluble20mg/mL, clear|
|Endurobol Application||A selective and potent PPARβ agonist;An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist.|