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L-Carnosine powder (305-84-0)

L-Carnosine is a protein building block that is naturally produced in the body. It is found in muscles when…f…….

 


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

 

Description

L-Carnosine powder (305-84-0) video

 

L-Carnosine powder (305-84-0) Specifications

Product Name L-Carnosine powder
Chemical Name beta-Alanyl-L-histidine

Karnozin

Carnosine

Brand Name L-Carnosine powder
Drug Class Anti-aging peptide
CAS Number 305-84-0
InChIKey CQOVPNPJLQNMDC-ZETCQYMHSA-N
Molecular Formula C9H14N4O3
Molecular Weight 226.236 g·mol−1
Monoisotopic Mass 226.10659 g/mol
Melting Point  253 °C (dec.)(lit.)
Freezing Point N/A
Biological Half-Life N/A
Color White
Solubility  Soluble in water, and almost transparency
Storage Temperature  2-8°C
Application

 

What is L-Carnosine?

L-Carnosine (beta-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.

L-Carnosine and carnitine were discovered by Russian chemist V.Gulevich.Researchers in Britain,South Korea,Russiaand other countries have shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturatedaldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. Carnosine is also a zwitterion, a neutral molecule with a positive and negative end.

Like carnitine, carnosine is composed of the root word carn, meaning flesh, alluding to its prevalence in animal protein. A vegetarian (especially vegan) diet is deficient in adequate carnosine, compared to levels found in a standard diet.

Carnosine can chelate divalent metal ions.

L-Carnosine can increase the Hayflick limit in human fibroblasts,as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.

 

l-carnosine benefits

  1. New types of food additives.
  2. Carnosine is composed of a β alanine and histidine dipeptide, animals can be synthesized in the body.
  3. Carnosine caused by free radicals and metal ions significantly inhibited lipid oxidation in meat processing carnosine can inhibit lipid oxidation, color protection. Carnosine and phytic acid oxidation resistance beef. Diets supplemented with 0.9 g / kg carnosine can improve the color and improve the oxidative stability of skeletal muscle, has a synergistic effect with vitamin e.
  4. In the use of cosmetics that can prevent skin aging and skin whitening effect, carnosine can prevent free radical caused by smoking, which is more than the sun’s rays free radicals damage the skin and radicals are highly reactive atoms or radicals in the human body, can be oxidation of other substances in the body.
  5. Carnosine has antioxidant, which is a natural antioxidant.
  6. People on cloudy eye lens transmittance is enhanced. Used as raw material in carnosine antioxidant agents can treat senile cataracts.
  7. Olfactory sensing object, can promote wound healing, especially used in surgical treatment of oral medication.

 

l-carnosine benefits for skin

  1. L-Carnosine powder is of interest as an anti-aging product because of its effects on advanced glycosylation end-products (AGEs). AGEs are abnormal, cross-linked, and oxidized proteins that might play a role in the aging process.
  2. L-carnosine helps to prevent skin collagen cross-linking which leads to loss of elasticity and wrinkles.
  3. L carnosine also acts as a regulator of zinc and copper concentrations in nerve cells, helping to prevent overstimulation by these neuroactive in the body substantiates all of the above and other studies have indicated further benefits.
  4. L Carnosine is a SuperAntiOxidant that quenches even the most destructive free radicals: The hydroxyl and the peroxyl radicals, superoxide, and singlet oxygen. Carnosine helps to chelate ionic metals(flush toxins from the body).

 

Pure l-carnosine powder uses and application:

  1. Protects epithelial cell membranes in the stomach and restores them to their normal metabolism;
  2. Acts as an antioxidant and protects the stomach from alcohol and smoking-induced damage;
  3. Has anti-inflammatory properties and moderates production of interleukin-8;
  4. Adheres to ulcerations, acts as a barrier between them and stomach acids and helps to heal them.

 

Reference:

  1. L-carnosine as an adjuvant to fluvoxamine in treatment of obsessive compulsive disorder: A randomized double-blind study. Arabzadeh S et al. Hum Psychopharmacol. (2017)
  1. Physiology and pathophysiology of carnosine. Boldyrev AA et al. Physiol Rev. (2013)
  1. L-Carnosine’s dose-dependent effects on muscle sympathetic nerves and blood flow. Horii Y et al. Neurosci Lett. (2015)
  1. Novel Facial Cream Containing Carnosine Inhibits Formation of Advanced Glycation End-Products in Human Skin. Narda M et al. Skin Pharmacol Physiol. (2018)
  1. Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products. Babizhayev MA et al. Life Sci. (2006)
  1. Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study. Garre A et al. Clin Cosmet Investig Dermatol. (2017)

 

PRECAUTION AND DISCLAIMER:

This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

 


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