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AICAR (2627-69-2)

AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity(AMPK)………


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1277kg/month

Description

AICAR (2627-69-2) video

 

AICAR (2627-69-2) Description

AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity(AMPK). AICAR is an intermediate in the generation of inosine monophosphate. AICAR is being clinically used to treat and protect against cardiac ischemic injury, it can enter cardiac cells to inhibit adenosine kinase and adenosine deaminase. It enhances the rate of nucleotide re-synthesis increasing adenosine generation from adenosine monophosphate only during conditions of myocardial ischemia. AICAR increases glucose uptake by inducing translocation of GLUT4 and/or by activating the p38 MAPK pathway. Currently, the drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.

AICAR (2627-69-2) Specifications

Product Name AICAR
Chemical Name 1-ribosyl-4-carboxamido-5-aminoimidazole, ARA 100, ARA-100, ARA100, GP 1 110, 5-aminoimidazole-4-carboxamide 1-ribofuranoside, 5-aminoimidazole-4-carboxamide riboside, acadesine, AICA ribofuranoside, AICA riboside, aminoimidazole carboxamide ribonucleoside, arasine, Z-riboside
Brand Name No data for available
Drug Class SARM
CAS Number 2627-69-2
InChIKey RTRQQBHATOEIAF-UUOKFMHZSA-N
Molecular Formula C9H14N4O5
Molecular Weight 258.23
Monoisotopic Mass 258.096 g/mol
Melting Point  214-215 °C
Freezing Point 214 °C
Biological Half-Life Very short
Color tan
Solubility  H2O: >10 mg/mL
Storage Temperature  −20°C
AICAR Application AMPK activator

 


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Shangke Chemical is a high-tech enterprise specializing in active pharmaceutical intermediates (APIs). To control the quality during production, a large number of experienced professionals, a first-class production equipment and laboratories are the key points.

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