Raw Compound 7P powder (1890208-58-8) video
Raw Compound 7P powder (1890208-58-8) Description
Raw Compound 7P powder which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina. in an animal model of optic nerve injury, Raw Compound 7P powder was shown to induce growth of gap-43 positive axons, indicating that the in vitro neurite outgrowth activity of Raw Compound 7P powder translates into stimulation of axon regeneration in vivo.further optimization of Raw Compound 7P powder and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies.
Raw 2-[(2-methoxyphenyl)[(4-methyl phenyl) sulfonyl] amino]-N-(4-methoxy-3-pyridinyl) acetamide (Compound 7P) powder (1890208-58-8) Specifications
| Product Name | 2-[(2-methoxyphenyl)[(4-methyl phenyl) sulfonyl] amino]-N-(4-methoxy-3-pyridinyl) acetamide (Raw Compound 7P powder) |
| Chemical Name | 2-[(2-methoxyphenyl)[(4-methyl phenyl) sulfonyl] amino]-N-(4-methoxy-3-pyridinyl) acetamide (Raw Compound 7P powder) |
| Brand Name | Raw Compound 7P powder |
| Drug Class | Nootropic Drugs |
| CAS Number | 1890208-58-8 |
| InChIKey | NAXWKPFXCOBXLE-UHFFFAOYSA-N |
| Molecular Formula | C22H23N3O5S |
| Molecular Weight | 441.508g |
| Monoisotopic Mass | 440g/mol |
| Melting point | N/A |
| Freezing Point | N/A |
| Biological Half-Life | N/A |
| Color | White powder |
| Solubility | slightly soluble in water and in ethanol. |
| Storage Temperature | Store at room temperature, in sealed container, avoid strong heat and light. |
| Application | • Increases coordination • Improves mood • Helps fight fatigue • Prevents oxidation within the brain • Treats alcohol related brain damage |
Raw Compound 7P powder (1890208-58-8) Description
Raw Compound 7P (2-[(2-methoxyphenyl)[(4-methyl phenyl) sulfonyl] amino]-N-(4-methoxy-3-pyridinyl) acetamide) powder which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina. in an animal model of optic nerve injury, Raw Compound 7P powder was shown to induce growth of gap-43 positive axons, indicating that the in vitro neurite outgrowth activity of Raw Compound 7P powder translates into stimulation of axon regeneration in vivo.further optimization of Raw Compound 7P powder and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies.
Use of Compound 7P powder (1890208-58-8)
Compound 7p (2-[(2-methoxyphenyl)[(4-methyl phenyl) sulfonyl] amino]-N-(4-methoxy-3-pyridinyl) acetamide) showed the highest activity against cervical cancer cells. In a nude mouse xenograft model inoculated with HeLa cells, 7p showed dose-dependent inhibition of cervical tumour growth. Histopathological examination of excised tumour-bearing tissues showed that 7p improved the microstructure in a dose-dependent manner. Compound 7p also increased the proportions of HeLa cells in G0/G1 and S-phase and significantly decreased that of G2/M-phase. The effects of 7p on C-caspase-3, C-caspase-9, Bcl-2 and Bax expression in HeLa cells were also determined.
Tubulin polymerization assay, immunofluorescence studies, cell cycle analysis and competitive tubulin-binding assay strongly proved that 7p is a colchicine binding site inhibitor of tubulin.
Benefits of Compound 7P powder (1890208-58-8)
Compound 7p promoted regeneration of the crushed optic
Repair the damage head nerve
Recommended Compound 7P powder (1890208-58-8) Dosage
Compound 7p exhibited 100% inhibition of parasitemia on day 4 at multiple doses(100, 50, and 25 mg/kg) given for four consecutive days, but at 100 mg/kg, all mice survived and were cured, while at 50 mg/kg, three of five mice survived and two mice were cured, and at 25 mg/kg, none of the mice survived
