Ipamorelin (170851-70-4) video
Ipamorelin (170851-70-4) Description
Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor that selectively stimulates the ghrelin receptor and causes growth hormone release. The potency and efficacy of ipamorelin are similar to GHRP-6 but without increase plasma levels of ACTH or cortisol. Ipamorelin appears to enter the central nervous system and to activate GRLN receptors in the spinal cord.
Ipamorelin is also one of several synthetic met-enkephalin analogs that include unnatural D-amino acids. They were developed for their growth hormone (GH) releasing activity, then called GH secretatogues. They lack opioid activity but are potent stimulators of GH release. These secretatogues are distinct from the growth hormone releasing hormone (GHRH or GHRF) in that they share no sequence relation and derive their function through action at a completely different receptor, the ghrelin receptor.
Ipamorelin (170851-70-4) Specifications
|Molecular Weight||711.868 g/mol|
|Monoisotopic Mass||711.386 g/mol|
|Biological Half-Life||About 2 hours|
|Color||White or white to beige powder|
|Solubility||Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.|
|Application||Use to reduce the symptoms of postoperative ileus is a gastrointestinal dysfunction arising due to abdominal surgery. Symptoms include abdominal distention, vomiting, nausea, constipation and anorexia.|