Alpha-lactalbumin (9013-90-5) video
Alpha-Lactalbumin powder Specifications
|Product Name||Alpha-lactalbumin (9013-90-5)|
|Chemical Name||α-Lactalbumin; LALBA |
lactalbumin, alpha-; alpha-lactalbumin; LYZL7; lysozyme-like protein 7; lactose synthase B protein;
|Drug Class||Biochemicals and Reagents, Casein and Other Milk Proteins, Proteins and Derivatives|
|Molecular Weight||14178 Da|
|Color||White to off white powder|
|Application||alpha lactalbumin powder has used in food, supplement, break milk.|
Alpha-lactalbumin (9013-90-5) Overview
Lactalbumin, also known as “whey protein”, is the albumin contained in milk and obtained from whey. Lactalbumin is found in the milk of many mammals. There are alpha and beta lactalbumins; both are contained in milk.
Scientific studies suggest that certain types of lactalbumin (whey protein) can significantly improve immune responsiveness and increase levels of glutathione systemically in animals and possesses antiviral (against viruses), anti-apoptotic (impede cell death) and anti-tumor (against cancers or tumors) activities in humans.
What is Alpha-Lactalbumin ?
Alpha-lactalbumin is a natural whey protein containing a naturally high content of all essential and branched-chain amino acids (BCAA), making it a unique protein source. The most significant amino acids in alpha-lactalbumin are tryptophan and cysteine, together with the BCAAs; leucine, isoleucine and valine.
Due to the high content of branched-chain amino acids (BCAA, ~26%), especially leucine, alpha-lactalbumin effectively supports and stimulates muscle protein synthesis, making it the ideal protein source for improving muscle health and help prevent sarcopenia during ageing.
Alpha-lactalbumin is the protein found in the second-highest amount in whey protein isolate at about 17%. It has all the benefits of whey protein; i.e., it is a complete source of protein that is high in EAAs, rich in branched-chain amino acids (BCAAs), has high digestibility, and is lactose- and fat-free.
It is the unique amino acid composition that makes alpha-lactalbumin a perfect protein option for individuals seeking a variety of benefits.
Alpha-lactalbumin is rich in essential and conditionally essential amino acids and is a dominant protein in human milk. It is suitable for a variety of medical nutrition applications such as UHT drinks, bars and powders.
Alpha-lactalbumin is a particularly rich source of the amino acids tryptophan and cysteine. Of these two, cysteine stands out as a rate-limiting amino acid for the formation of glutathione (GSH) –an antioxidant known to minimize oxidative stress in the human body.
Alpha-lactalbumin is naturally high in tryptophan
Tryptophan is one of the most limited amino acids in food proteins. However, alpha-lactalbumin provides 48 mg of tryptophan per gram of protein, its highest content in all food protein sources.
Alpha-lactalbumin as a protein source increases blood tryptophan levels, which promotes the synthesis and availability of serotonin in the brain. In turn, serotonin supports the production of melatonin, the hormone that helps regulate sleep patterns.
Alpha-lactalbumin is high in cysteine
Alpha-lactalbumin provides 48 mg of cysteine per gram of protein. Cysteine is the direct precursor to the antioxidant glutathione, which is involved in body processes that support the immune system, build and repair tissues, and protect against oxidative damage.
Alpha-lactalbumin is a rich source of sulfur-containing amino acids
Alpha-lactalbumin whey protein contains a highly unique 5:1 ratio of cysteine to methionine – a ratio that is physiologically favorable. Methionine is central to the methylation cycle, a crucial process that requires folate, vitamin B12, and choline, and is essential for the synthesis of nucleotides, the building blocks of DNA.
Whey protein (including alpha-lactalbumin) is a rich source of essential amino acids.
Whey protein is high in EAAs, the nine of 20 amino acids that must come from the diet because the body can’t synthesize them. Furthermore, BCAAs, specifically leucine, plays a direct role in initiating muscle protein synthesis.
EAAs support rebuilding, repair, and synthesis of muscle proteins even in the presence of lower protein or lower caloric intake.
Alpha-lactalbumin whey protein contains bioactive peptides
Bioactive peptides possess prebiotic properties and have a unique potential application for human health. Research suggests the specific effects of alpha-lactalbumin on the gut are in part from the bioactive peptides from the unique tryptophan and cysteine combination and other post-translational modifications of these amino acids.
As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding;variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.
Alpha-lactalbumin is present at a level of 0.02% to 0.03% in bovine milk, making isolation and purification a precise science. Its presence in human milk is much higher, about eight times more; thus, isolation and purification of alpha-lactalbumin enables the development of infant formula that more closely resembles human milk.
Alpha-lactalbumin as a protein source increases blood tryptophan levels, which promotes the synthesis and availability of serotonin in the brain. In turn, serotonin supports the production of melatonin, the hormone that helps regulate sleep patterns. Serotonin exerts multiple effects and is implicated in the control of the appetite, mood, sleep regulation, cognitive performance and the ability to cope with stress.
In the latest position stand on protein by the International Society of Sports Nutrition, alpha-lactalbumin is also promoted for its capacity to speed wound healing, which is vital for recovery from combat and contact sports.
LALBA(Alpha-lactalbumin ) has several biochemical functions, for example, calcium ion binding, lactose synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LALBA itself. We selected most functions LALBA had, and list some proteins which have the same functions with LALBA. You can find most of the proteins on our site.
alpha-lactalbumin whey protein supports athletes or individuals seeking to maintain or build muscle mass during periods of catabolic conditions, such as overnight fasting, weight loss, bed rest, aging, intense exercise/stress, or illness.
Studies have shown that consuming alpha-lactalbumin rich in tryptophan may improve sleep quality and morning alertness, cognitive performance under stress, and mood under stress.
Alpha-lactalbumin powder uses
- Alpha-lactalbuminpowder use as a component of infant formulas, to make them more similar to breast milk;
- Alpha-lactalbuminpowder use as a supplement to promote gastrointestinal health or modulate neurological function, including sleep and depression;
- Alpha-lactalbuminpowder use as a therapeutic agent with applications in conditions or diseases such as sarcopenia, mood disorders, seizures, and cancer.
- Layman D, Lönnerdal B, Fernstrom J. Applications for α-lactalbumin in human nutrition. Nutr Rev 2018;76(6):444-460.
- Booij L, Merens W, Markus C, Van der Does A. Diet rich in alpha-lactalbumin improves memory in unmedicated recovered depressed patients and matched controls. J Psychopharmacol 2006;20(4):526-535.
- Markus C, Olivier B, de Haan E. Whey protein rich in alpha-lactalbumin increases the ratio of plasma tryptophan to the sum of the other large neutral amino acids and improves cognitive performance in stress-vulnerable subjects. Am J Clin Nutr 2002;75(6):1051-1056.
- Alpha-lactalbumin production in human mammary carcinoma Science 1975 190: 673-.
- Comparison of the amino acid sequence of bovine alpha-lactalbumin and hens egg white lysozyme.K Brew et. Al The Journal of biological chemistry, 242(16), undefined (1967-8-25)
- Alpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs. Nielsen CH, Hui Y, Nguyen DN, Ahnfeldt AM, Burrin DG, Hartmann B, Heckmann AB, Sangild PT, Thymann T, Bering SB. Nutrients. 2020 Jan 17
- nvestigation and comparison of the anti-tumor activities of lactoferrin, α-lactalbumin, and β-lactoglobulin in A549, HT29, HepG2, and MDA231-LM2 tumor models. Li HY, Li P, Yang HG, Wang YZ, Huang GX, Wang JQ, Zheng N. J Dairy Sci. 2019 Nov