Aloin powder (1415-73-2) video
Aloin powder (1415-73-2) Specifications
|Product Name||Aloin powder|
|Chemical Name||▪ Aloin A
▪ Aloin (Mixture of A and B)
|Drug Class||Anti-inflammation,removing beverage peptide|
|Monoisotopic Mass||418.31 g/mol|
|Color||Lemon yellow crystalline powder|
|Solubility||Pyridine: 50 mg/mL, clear, dark red|
|Application||Aloin as an ant ineoplastic agent that enhances melanogenesis and transglutaminase activity.|
Aloin powder (1415-73-2) Description
Aloin powder is a natural chemical found in the skin of the Aloe Vera plant that has laxative effects when orally consumed by humans. Not to be confused with Acemannan (a beneficial compound in Aloe Vera), aloin powder has long been a point of controversy, as some found it to be a useful as a stimulant-laxative to treat constipation by inducing bowel movements. However, the negative side effects of aloin powder far outweigh any benefits and even make consumption of the chemical potentially dangerous.
Once ingested, aloin powder increases peristaltic contractions in the colon, which induces bowel movements. Aloin powder also prevents the colon from re-absorbing water from the gastrointestinal tract, which leads to softer stools. This effect is caused by aloin’s opening of chloride channels of the colonic membrane. In higher doses, these effects may lead to electrolyte imbalance, diarrhea, and abdominal pain, which are common side-effects of the aloin powder. Because aloin powder can potentially cause uterine contractions, pregnant women should avoid ingesting aloe products containing aloin powder in more than trace amounts.
In a study on consumption of aloe in rats and tilapia (with no separation of gel from aloin), significant negative health effects were found, including normocytic normochromic anaemia (low red blood cell count, but normal cells), hypoproteinaemia, and high AST levels. As many studies involving aloe gel (without aloin) have not observed these negative effects, it is possible that the negative effects could in large part be due to aloin powder.