NADH 2Na (606-68-8)

March 15, 2020
SKU: 129311-55-3
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NADH is a form of nicotinamide adenine dinucleotide (NAD) enzyme, an active coenzyme form of a compound and vitamin B3……….

 


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

NADH 2Na (606-68-8) video


 

Beta-Nicotinamide adenine dinucleotide disodium salt(NADH 2Na) Specifications

Product Name Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)
Chemical Name NADH (disodium salt); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide,disodiumsalt;beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, reduced;
CAS Number 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Molecular Formula C21H27N7Na2O14P2
Molecular Weight 709.4
Monoisotopic Mass 709.088661 g/mol
Melting Point 140-142℃
Color Yellow
Storage temp 2-8℃
Solubility H2O: 50 mg/mL, clear to nearly clear, yellow
Application Medicine; diet and nutritional supplements;

 

What is Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

NADH is a form of nicotinamide adenine dinucleotide (NAD) enzyme, an active coenzyme form of a compound and vitamin B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Salt, reduced, also known as Nicotinamide adenine dinucleotide, is a coenzyme in redox reactions. Its functions as a regenerating electron donor in catabolic processes including glycolysis, β-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). NADH disodium salt is also participates in cell signaling events, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. As the disodium salt of NADH, it is used in diet and nutritional supplements in the treatment of Parkinson’s disease, chronic fatigue syndrome, Alzheimer’s disease and cardiovascular diseases.

 

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) benefits

As a coenzyme of oxidoreductases, NADH disodium salt plays a vital role in the body’s energy production.

– NADH disodium salt may lead to better mental clarity, alertness, concentration, and memory. It may increase mental acuity and may increase mood. It can increase energy levels in the body and improve metabolism, brain power and endurance.

– Help people with clinical depression, high blood pressure or high cholesterol;

– Improve athletic performance;

– Delay the aging process and maintain the integrity of nerve cells to support the nervous system;

– May treat Parkinson’s disease, improve the function of neurotransmitters in the brain of patients with Parkinson’s disease, reduce physical disability and drug needs;

– Treatg chronic fatigue syndrome (CFS), Alzheimer’s disease and cardiovascular disease;

– Protect against the side effects of an AIDS drug called zidovudine (AZT);

– Oppose alcohol ’s effects on the liver;

– Jet lag

 

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) side effects:

At present, NADH disodium salt seems safe for most people when used appropriately and short-term, up to 12 weeks. Most people do not experience any side effects when taking the recommended amount each day, which is 10 mg.

However, there is no enough datas about the use of NADH disodium salt during pregnancy and breast-feeding., so they should stay on the safe side and avoid use.

 

Reference:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) – a new therapeutic approach to Parkinson’s disease. Comparison of oral and parenteral application. Acta Neurol Scand Suppl 1993;146:32-5.
  • Budavari S, ed. The Merck Index. 12th ed. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral reduced B-nicotinamide adenine dinucleotide (NADH) affects blood pressure, lipid peroxidation, and lipid profile in hypertensive rats (SHR). Geriatr Nephrol Urol 1998;8:95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral reduced B-nicotinamide adenine dinucleotide (NADH) affects blood pressure, lipid peroxidation, and lipid profile in hypertensive rats (SHR). Geriatr Nephrol Urol 1998;8:95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome? Antioxid Redox Signal 2015;22(8):679-85.
  • Dizdar N, Kagedal B, Lindvall B. Treatment of Parkinson’s disease with NADH. Acta Neurol Scand 1994;90:345-7.

 

PRECAUTION AND DISCLAIMER:

This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.