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Tranexamic Acid powder (1197-18-8)

Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived…….

 


Status: In Mass Production
Synthesized and Customized Available
Capacity: 1277kg/month

 

Description

Tranexamic Acid powder (1197-18-8) video

 

Tranexamic Acid powder (1197-18-8) Specifications

Product Name Tranexamic Acid powder
Chemical Name ▪ Cyklokapron

▪ Tranexamsaeure

▪4-(Aminomethyl)cyclohexanecarboxylic acid

▪trans-4-(Aminomethyl)cyclohexanecarboxylic acid

▪Transamin

Brand Name Cyklokapron
Drug Class whitening
CAS Number 1197-18-8
InChIKey GYDJEQRTZSCIOI-UHFFFAOYSA-N
Molecular Formula C8H15NO2
Molecular Weight 157.21 g/mol
Monoisotopic Mass 157.110279 g/mol
Melting Point   >300 °C
Freezing Point N/A
Biological Half-Life 3.1 hours
Color White powder
Solubility  water solubility: 1.67E+005 mg/L
Storage Temperature  N/A
Application ▪ Heart surgery

▪ Menstrual bleeding

▪ Whitening effect

 

What is Tranexamic acid?

Tranexamic Acid is a synthetic amino acid that functions as a skin-conditioning agent and astringent. In cosmetics, it functions on skin as a barrier repair ingredient and seems able to help skin recover from damage. It an effective skin lightener when used in cosmetic formulations. There’s a growing body of research showing that tranexamic acid also has an inhibitory effect on melanin (skin pigment) production, meaning topical applications of effective amounts may improve brown skin discolorations associated with melisma.

 

Tranexamic acid powder for skin?

Tranexamic Acid is a white powder that is an effective skin lightener when used in cosmetic formulations. The lightening effects of tranexamic acid were discovered accidentally during a medical procedure.

Tranexamic acid works by stopping tyrosinase activity, which reduces the formation of melanin. It is soluble in water and glacial acetic acid (anhydrous).

Please note that this is for COSMETIC USE ONLY, not to be consumed, injected, or used in any way other than as a topical cosmetic ingredient. Tranexamic acid must be formulated into a cosmetic cream, lotion, or serum, it cannot be applied directly to skin in its powdered form.

 

Tranexamic acid powder uses and application

Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding.

Trauma

Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury.

Heart surgery

Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin.

Orthopedic surgery

Tranexamic acid is used in orthopedic surgery to reduce bloodloss. It is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced.

Menstrual bleeding

Used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. A recent study showed patients treated with tranexamic acid are more likely to develop thrombosis and necrosis in their fibroids, and may result in pain and fever.

Dentistry

Tranexamic acid is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.

Other usesIn obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with syntocinon/oxytocin and fundal massage.

In hemophilia

Tranexamic acid is also useful in the treatment of bleeding as a second line treatment after factor VIII in patients (e.g. tooth extraction).

Whitening effect

Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%

Tranexamic Acid ,a mechanism of work that the validity of the whitening, not only can play excellent cleaning effect, the further reduce melanin, fade melanin generation spots, can prevent ultraviolet ray to skin damage and play excellent whitening effect! So the more stable, not easy the acid by temperature environmental damage, without excitant etc many advantages, and to ensure the it in the whitening and don’t stimulate the skin.

 

Reference:

  1. Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review. Kim HJ et al. Acta Derm Venereol. (2017)
  2. Tranexamic Acid in the Treatment of Melasma: A Review of the Literature. Perper M et al. Am J Clin Dermatol. (2017)
  3. Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies. Taraz M et al. Dermatol Ther. (2017)

 

PRECAUTION AND DISCLAIMER:

This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

 


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