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Lanreotide (108736-35-2)

Lanreotide is a somatostatin analogue that suppresses GH/IGF-I hypersecretion in acromegaly patients and used to Lanreotide………


Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1627kg/month

Description

Lanreotide (108736-35-2) video

 

Lanreotide (108736-35-2) Description

Lanreotide is a somatostatin analogue that suppresses GH/IGF-I hypersecretion in acromegaly patients and used to manage neuroendocrine tumours.

Lanreotide is a a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide inhibits the secretion of growth hormone (GH) by binding to pituitary somatostatin receptors, and may inhibit the release of various other hormones, including thyroid stimulating hormone (TSH) and the gastroenteropancreatic hormones insulin, glucagon and gastrin. This agent also decreases circulating total and free insulin-like growth factor 1 (IGF-I). Lanreotide exhibits a high binding affinity for somatostatin receptor 2 (SSTR-2) and a lesser binding affinity for SSTR-5. However, compared to octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

Lanreotide (108736-35-2) Specifications

Product Name Lanreotide
Chemical Name (4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-(naphthalen-2-yl)propanamido)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-10-(4-aminobutyl)-16-(4-hydroxybenzyl)-7-isopropyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
Brand Name Somatuline; Lanreotide; Ipstyl; BIM 23014; Somatulin; Lanreotide Autogel.
Drug Class Peptide
CAS Number 108736-35-2
InChIKey PUDHBTGHUJUUFI-SCTWWAJVSA-N
Molecular Formula C54H69N11O10S2
Molecular Weight 1096.33g
Monoisotopic Mass 1095.467 g/mol
Melting Point  180-185°C
Freezing Point N/A
Biological Half-Life 2 hours
Color White powder
Solubility  slightly soluble in DMSO and methanol
Storage Temperature  0 – 4 C for short term (days to weeks), or -20 C for long term (months).
Application Lanreotide is a somatostatin analogue that suppresses GH/IGF-I hypersecretion in acromegaly patients and used to manage neuroendocrine tumours.

 


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