What is Glutathione?
Glutathione, whether in glutathione injections, glutathione cream or the naturally occurring form of it, is a minute protein comprising of three amino acids, namely cysteine, glutamate, as well as glycine. Although glutathione is a natural liver product, it is also a key chemical substance in fruits, meat and vegetables.Glutathione is administered orally, inhaled, or through injection to replenish its level in the body for various biological processes and benefits. Glutathione function plays an important role in immune system boosting, lung disease treatment, chemotherapy side effect relief, and anemia prevention, among other functions.
How does Glutathione work?
Glutathione function comes in handy in an array of processes that occur in a human body to present various glutathione benefits. These processes include immune response the repair and building of tissues as well as protein and chemical processing.
Also, known for its outstanding oxidation power, glutathione improves the manner in which the human body utilizes and recycles oxidants such as vitamins C and E, CoQ10 and alpha lipoic acid.
What are the benefits of Glutathione in the body?
With the right glutathione dosage for supplementation or ample production of it in the body, a person stands high chances to enjoy various health benefits as a result of sufficient supply of the molecule in the body. The key glutathione benefits include:
1.As a potent antioxidant
Oxidative stress is a major contributing factor to aging and various illness. This happens when the production of free radicals outweighs the ability of the body to fight these free radicals.
When the imbalance occurs, the excess free radicals damage the body cells, making one age fast and prone to various diseases. Some of the diseases that can occur as a result of excessive oxidative stress include diabetes, cancer, asthma, arthritis and inflammatory disorders.
On the other hand, when the body has reasonable level antioxidants such as glutathione, it is able to fight off the present free oxidants. Because of its antioxidative power and the ability to exist in the body cells in high concentrations, glutathione function is very effective in helping the body counteract various oxidants and their destructive impacts.
2.As a detoxifier
Glutathione detoxify toxic substances in our bodies. Due to the foods and other substances that people consume, their bodies are prone to toxins that adversely affect their organs and biological processes. Besides, the body itself can produce toxic substances during its usual processes.For instance, in the last phase of the energy production process, the body can produce superoxide. Considering superoxide has excess amounts of electrons, it can be poisonous to the cell membranes, DNA, mitochondria, among other body components near it.
Fortunately, when your body has sufficient levels of it, glutathione detoxify and neutralizes superoxides, protecting the body from their toxic effects. In addition to superoxides, glutathione also extinguishes and neutralizes many other types of toxic molecules that could be present in your body.
3.For skin and anti-aging
Everybody wants to have perfect skin. Unfortunately, with the aging process, hormonal changes, some lifestyle factors such as poor nutrition and physical exercise habit, your skin could be the opposite of your expectations. Worse still, anti-aging skincare products such as moisturizers, creams and serums might turn out to be unhelpful in your strive to achieve flawless skin.
If that’s your current situation, it’s advisable that you try glutathione for skin improvement.
a try. Glutathione for skin plays a crucial role in cellular and mitochondrial functions, and so, has the capability to promote the healing of the damaged body cells contributing to your skin flaws.
Besides, glutathione supports the regeneration of body cells, and this is a crucial step towards the restoration of your skin health.
Various scientific studies have repealed the ability of glutathione for skin pigmentation and wrinkle appearance reduction. Also, the antioxidant has been found to improve skin elasticity. The overall effect is a younger-looking person with a healthy and beautiful skin tone and texture.
4.For brain and heart
With advanced age, people normally experience memory issues as a result of neurodegeneration. This happens when a significant amount of brain neurons gets damaged or die. As a result, the brain shrinks and is not able to function to its full capacity.
Unfortunately, people can’t run away from such effects of the aging process. On the other hand, and fortunately, glutathione supplementation to improve glutathione level in the body can be of great help in reversing or slowing down the aging process and the associated signs and symptoms. The antioxidant eases and reduces the neural tissue damage rate, and facilitate the repair of the damaged neural tissues.
In a study conducted in 2017, researchers found out that intranasal glutathione contributed to the improvement of Alzheimer’s symptoms among the patients who have the mental condition.
Glutathione antioxidant is also crucial for heart health. This among the key glutathione benefits, and it trickles down to the ability of the glutathione molecules to counteract “lipid oxidation” in the body.
The initial stage of any heart disease is characterized by an arterial plaque in the walls of an artery. Then, the plague breaks off, causing an obstruction to the blood flow. Consequently, a heart attack or stroke occurs.
Fortunately, when you have ample glutathione supply in your body, the antioxidant collaborates with an enzyme known as glutathione peroxidase to inactivate the peroxinitrites, peroxides, free radicals, as well as the superoxide. If uncontrolled, all of these compounds contribute to lipid oxidation which adversely affect your heart health. Therefore, glutathione benefits your heart by protecting it from damages that could arise due to the presence of the compounds in your body.
Glutathione inflammation relief benefit is another thing that makes glutathione popular. Nearly any chronic illness, including diabetes, cancer and heart disease, is characterized by an inflammation.
Inflammations are also common in or around injured body areas. Although inflammatory responses are normally part of the healing process, sometimes they can persist unnecessarily for a long time, causing a reason for alarm. This is where glutathione inflammation relief benefit comes in handy.Various studies suggest that glutathione supplement or the internally-produced glutathione in the body controls the increase and decrease of inflammation as the body immune response requires. Allegedly, the glutathione molecules achieve this by influencing a person’s white cells. As such, they’re able to control chronic inflammations.
6.For immune system
Glutathione foods or glutathione supplement also provide your body with enough glutathione molecules to boost your immune system. With a robust immune system, your body can fight various disease pathogens effectively, thanks to glutathione vitamin c potential similarity in supporting the immune system.
According to scientific studies, active glutathione improves the functionality of white cells like natural killers as well as T cells. With the boost, T cells produce a higher number of substances responsible for fighting bacterial and viral infections. These substances include interferon-gamma as well as interleukins-2 and interleukin-12.
Researchers in one study discovered that glutathione antioxidant improved the potential of natural killer cells to kill pathogenic organisms by 200% after six months of using glutathione supplement. Besides, glutathione foods and supplements seem to directly assist macrophages fight Mycobacterium tuberculosis. Mycobacterium tuberculosis is a bacterium that leads to tuberculosis.
Infections like Epstein–Barr virus, Lyme diseases and hepatitis can suppress your immune system. However, with ample supply of glutathione antioxidant, the immune system can effectively resist the suppressive effect of such diseases.
Researchers suggest that there’s a direct correlation between autism and low glutathione levels. This follows the evidence showing that autistic children have lower glutathione levels as compared to kids without the disorder.
Fortunately, with the right glutathione dosage and adherence to the supplement, children with autism can get better. A 2011 study shows that glutathione oral supplements or glutathione injections can minimize some autism effects.
Glutathione cancer benefit is another thing that makes health specialists emphasize the importance of sufficient glutathione in the human body. According to numerous studies, that glutathione cancer prevention ability is evident. These studies suggest that glutathione mechanism helps in cancer progression prevention.
There’s also another glutathione cancer effect. Some healthcare specialists administer glutathione injections to cancer patients as a way of preventing the adverse chemotherapy effects.
9.For weight loss
People who are struggling with belly fat or obesity can also achieve their weight goals by eating glutathione foods or taking glutathione supplement. In most cases, toxins and free radicals resulting from heavy carb and sugar consumption are the major cause of obesity and belly fat.
The excessive consumption of either of the two makes the body to store more fat and burn fewer calories. As a result, you gain more weight, and perhaps your belly experiences higher fat accumulation. If left unattended, obesity can trigger inflammatory diseases like cancer.
Fortunately, glutathione injections are as effective as Vitamins D, B12 and D in helping the body flush out toxins. Glutathione mechanism supports the body in burning calories and fat, thus promoting weight loss and better body shape.
10.For Peripheral Vascular Disease
Peripheral Vascular Disease is a health condition that’s caused by the clogging of the peripheral arteries. It mostly affects the legs. Glutathione can help you avoid this disease by improving the circulation of blood throughout your body.
If you already have the disease, glutathione oral or injection administration can ease the symptoms due to the improved blood circulation. With adherence to the right glutathione dosage, it’ll be just a matter of time before you start walking without feeling any pain.
Athletic performance is also among glutathione uses. Studies have discovered that glutathione can improve the performance of an athlete if he/she uses glutathione supplement before the sports activity.
In one study, eight men were given 1,000 mg of glutathione prior to starting an athletic exercise. The other men who were used as the participants of the study were placed on placebo.Upon the completion of the athletic exercise, the researchers noted that the group that received glutathione supplement performed significantly better than the placebo group. The former experienced less fatigue and lower amount of blood lactic acid as compared to the latter. Normally, high lactic acid levels in the body heightens fatigue, reduces blood pressure and cause muscle aches and respiratory issues.
Glutathione powder which has been processed into consumable glutathione injections or supplements protects an athlete from such issues. This helps them to perform better in their workouts and competitions.
In most cases, diabetes or chronic high blood sugar is linked to glutathione deficiency
in human body. The high sugar levels can cause oxidative stress which leads to tissue damages.
As such people suffering from diabetes might experience a remarkable symptom relief upon addressing their glutathione deficiency. An effective solution to this is improved glutathione oral intake by taking glutathione foods or glutathione supplement. Alternatively, they can glutathione injections can also be used to fix glutathione deficiency.
13.For Parkinson’s syndrome
Some studies show that maintaining sufficient amount of glutathione in the body may contribute to the relief of Parkinson’s disease symptoms. The disease affects the integrity and functionality of the central nervous system, making a person experience symptoms like tremors and rigid joints.
Researchers have come up with findings that suggest that glutathione function could be a possible therapy for alleviating the symptoms of Parkinson’s disease. However, there’s not sufficient evidence to prove that glutathione oral supplementation could be safe and effective in this. Further research is in progress to determine the effeteness and safety of glutathione oral supplementation.
Being a crucial intercellular oxidant, glutathione cream can boost the health of your hair. Glutathione inflammation relief is a great benefit that those who experience scalp inflammations that lead to hairless appreciate.
Besides, if you want to avoid the graying of your hair, you need to ensure that you maintain healthy glutathione levels in your body. research shows that glutathione deficiency promotes hair graying. The glutathione mechanism to achieve this involves preventing oxidation stress by through detoxification and neutralization of oxidants.
Who need Glutathione? What is the usual dosage?
Everybody needs glutathione for optimal body performance, disease prevention and to look healthy and attractive.
However, young people with glutathione deficiency and those at advanced age need glutathione supplementation to avoid or experience a relief of the deficiency’s symptoms/impacts. They can take glutathione supplements orally or through injections.
At the moment, there’s no sufficient scientific proof to establish the right glutathione dosage. However, researchers have tentatively proposed for certain glutathione dosage for specific medical conditions. These amounts depend on various factors such as age, gender as well as the medical history of a person. Therefore, glutathione dosage differs from one person to another, even among patients with a common medical condition.
How to increase our Glutathione?
There are various ways in which you can boost glutathione level in your body. In case you don’t have a severe glutathione deficiency, eating glutathione-rich diet should help you overcome the deficiency. Some of the foods that you can count on for this purpose include vegetables (cabbages, spinach, broccoli, Brussel sprouts), walnuts, tomatoes, cucumber, chives, garlic and freshly prepared meat. Research shows that these foods are rich in glutathione.
drinking plenty water consistently (about 64 ounces every day), sleeping for 7 to 8 hours every day/night, avoiding stress, and performing physical exercises least five days every week will help your body to increase its glutathione production capacity.
Another way of increasing glutathione level in your body is taking glutathione supplements. These supplements can be taken orally or as injections. They are particularly very helpful for people who’ve been confirmed to have glutathione deficiency. The supplements are also available in the form of creams while others are designed for (intravenous) IV application.
What causes glutathione deficiency?
Glutathione deficiency mainly occurs due to various factors. One is the aging process. Your glutathione level keeps on declining as you grow older. Studies show that the production of glutathione in the human body cells reduces a rate of about 10 percent every ten years for a person who’ve attained or surpassed the age of 20.
The second factor is poor nutrition. Failure to eat the right quantities of glutathione-rich foods (seven to nine servings of organic veggies and fruits daily) leads to low supply of glutathione in your body.
Other factors that contribute to glutathione deficiency include chronic stress, anxiety, depression, excessively strenuous physical exercises and light pollution. Exposure to toxic and harmful substances such as acetaminophen, pesticides, benzopyrenes and housewares chemicals is also another factor.
Are there any glutathione side effects?
So far, there’s no sufficient scientific evidence of glutathione side effects. Nevertheless, some user reviews suggest that glutathione side effects can prevail, but in rare instances. According to the reviews, in some cases, one can experience cramps, rashes or bloating after taking glutathione supplements. Fortunately, most of these glutathione effects are mild and vanish after a fairly short time.If you are asthmatic, it is advisable that you avoid inhaled glutathione. Using this form of glutathione can trigger an allergic reaction in your body. Also, expectant and breastfeeding women are advised against using glutathione supplements to avoid possible serious glutathione side effects.
Glutathione’s current status and application in the market
Glutathione is available as Reduced Glutathione (GSH) or Oxidized Glutathione (GSSG) in the market. Various statutory drug regulatory authorities have approved the sale and purchase of both forms of glutathione, but under certain terms and conditions.
Glutathione powder has an array of applications. Besides being used in pharmaceuticals, many manufacturers make glutathione powder buy to use it as a key ingredient in foods, health products and cosmetics.
Where can we get Glutathione?
You can get from glutathione foods that are rich in it from your local wet market or garden. If you want glutathione powder or glutathione supplements, whether glutathione creams, pills, solutions, tablets, syrups or sprays, you can get them from your local drug store or a store specializing with dietary supplements in your locality.
However, the most convenient place to get glutathione powder or glutathione supplements is on the internet. There are many online drug or dietary supplement stores that you can count on for hassle purchase of glutathione. However, you need to ensure that you are dealing with a trustworthy online seller before money changes hands. This applies even when you want to make a glutathione powder buy.
Glutathione is an effective antiaging substance that we all need in our bodies. Glutathione detoxify toxic substances in our bodies and plays an important role in slowing down or even reversing the aging process. It provides an array of health benefits, including cancer prevention and Parkinson’s disease symptom relief. You can get glutathione from specific foods or from glutathione powder supplements available at physical and online drug/dietary supplement stores.
Glutathione is a minute protein comprising of three amino acids, namely cysteine, glutamate, as well as glycine. This article focuses on glutathione benefits, uses, side effects and dosage. You’ll also see where to get glutathione.
Deponte, M. (2013). Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes. Biochimica et Biophysica Acta (BBA)-General Subjects, 1830(5), 3217-3266.
Noctor, G., Mhamdi, A., Chaouch, S., Han, Y. I., Neukermans, J., Marquez‐Garcia, B. E. L. E. N., … & Foyer, C. H. (2012). Glutathione in plants: an integrated overview. Plant, cell & environment, 35(2), 454-484.
Owen, J. B., & Butterfield, D. A. (2010). Measurement of oxidized/reduced glutathione ratio. In Protein misfolding and cellular stress in disease and aging (pp. 269-277). Humana Press, Totowa, NJ.
Ribas, V., García-Ruiz, C., & Fernández-Checa, J. C. (2014). Glutathione and mitochondria. Frontiers in pharmacology, 5, 151.
Smeyne, M., & Smeyne, R. J. (2013). Glutathione metabolism and Parkinson’s disease. Free Radical Biology and Medicine, 62, 13-25.
Traverso, N., Ricciarelli, R., Nitti, M., Marengo, B., Furfaro, A. L., Pronzato, M. A., … & Domenicotti, C. (2013). Role of glutathione in cancer progression and chemoresistance. Oxidative medicine and cellular longevity, 2013.