Everything about MK-2866 (Ostarine)
MK -2866, popularly known as Ostarine, was initially developed by Merck, a pharmaceutical company. A firm known as GTX took the initiative to test this drug with the aim of combating muscle wasting diseases; it is currently on clinical testing phase. It is a form of SARM (Selective Androgen Receptor Modulator). Unlike other performance-enhancing medicines, MK-2866 works better and is free of serious side effects thus a very effective drug for bodybuilders. MK-2866 (Ostarine) builds and preserves lean muscle mass in addition to healing bone and muscle tissues.
Contrary to other steroids, SARMs can work on bones or muscles individually. For these reasons, users of Ostarine are safe from increased estrogens and testosterone suppression. Ostarine has gained popularity among athletes and bodybuilders due to its minimal side effects. It is by far much better than other steroids and perhaps the best SARM. So far, however, it has not been recommended for human consumption. MK-2866 (Ostarine) is among the few SARMs that are still on clinical trial. If MK-2866 benefit outweigh the risks, soon it will be approved for medical use. Its use in sports was banned in 2008 by World Anti-Doping Agency; this rule might remain so even after Ostarine is approved medically.
How Does MK-2866 Work On the Body?
It is well known that androgens accelerate the build-up of muscle mass. This explains why women have fewer muscles than men since androgen is the major male sex hormone. When these hormones are stimulated none selectively by steroids, they cause serious side effects which may or may not be reversible.
Just like other SARMs, Ostarine MK-2866 attaches itself to an androgen receptor. During this process, however, dihydrotestosterone (DHT) is not converted into estrogen-like it is the case when other steroids are used. Estrogen conversion is one of the major drawbacks of using steroids; it leads to adverse side effects such as hair loss, increased body fat and man boobs.
To build muscle mass, Ostarine boosts water retention and protein synthesis processes in the body. Mainly, it works on muscle and bone receptor cells thus displaying high anabolic properties within the body. It therefore develops and protects muscle tissues thus stands out to be the best SARM and very popular among users.
To some extent MK-2866 triggers satellite cells which aid in regenerating and remodeling muscles. Also, it activates connective tissue cells that play a role in muscle injury recovery. GTX has studied Ostarine SARM eight times. The results were clear that it escalates and strengthens lean muscle mass. These results are quite reliable since the study was carried out eight times with a sample of six hundred participants.
As discussed above, it is clear that MK-2866 boosts muscle mass as well as preserving them. Precisely, Osterine can be used for bulking and cutting stages during training programs. Users gain lean muscles without aching joints, man boobs or excessive water retention like it is the norm when using other steroids.
(1) Ostarine Bodybuilding Benefits
With a dosage of 25mg daily, research indicated that bodybuilders gained 6-8lbs during bulking cycles. Cancer patients, on the other hand, gained 2-3lbs after administering 3mg/day of ostarine dosage for four months. Most people who have used ostarine MK-2866 find it very efficient since it builds up clean and dry muscles without worries of any harm. It is the best SARM in the market currently. Basing on the ostarine reviews by bodybuilders, it releases all steroid drug benefits without causing unnecessary side effects. They term it as a clean drug that builds pure muscle mass while burning fat.
Comparing to low dosages of other steroids like Primobolan, Oxandrolone or Equipoise, the gains when using ostarine dosage are not very dramatic. However, these gains are healthier, permanent and the side effects are minimal if not none. Steroid users administer MK-2866 as a PCT while others take it in between steroid cycles to ensure that the muscles gained are maintained. Others administer PCT (Post Cycle Therapy) shortly after an MK-2866 cycle.
Ostarine users’ claim that the muscles they gain during cycles are not difficult to maintain. Arguably, this is a more important benefit than muscle mass building effect. Users would most definitely prefer to gain less mass that can last longer than building more muscles that disappear immediately after the bulking cycle. Either way, ostarine users maintain that they enjoy maximum gains all through the bulking cycles. Women prefer Ostarine to other steroids since it does not trigger male-like features such as, hair growth on the face, deepened voice among others.
- Intensified protein synthesis
- Minimal or zero water retention
- Clean, dry and pure lean muscle gains
- Maximized, stamina, lifting endurance and strength
- Muscle mass gain of 6-8lbs
- Pre-cycle and liver support supplement are not needed
- No reports of increased aggression
- Post-cycle crashes are not experienced
- Fewer muscle gains as compared to other steroids
- Great and prolonged workouts
- A more significant percentage of women report more fat loss and muscle gains than men.
- Improved sense of well being
(2) Ostarine Cutting Benefits
Maintained muscle mass, fat loss, and zero strength loss are some of the effects experienced by MK- 2866 (Ostarine) users during cutting cycles. The major adverse effect of cutting cycles is lean muscle mass loss. This is why most bodybuilders use Ostarine since it burns fat while at the same time it prevents muscle loss.
Typically, it is impossible to lose weight or burn fats without minimizing the number of calories consumed. During this period, the body breaks down any form of energy accumulated in the system, proteins stored in the muscles included. Ostarine hampers this process thus the proteins are not converted to energy, but still, body fat is burned. Amazingly, users can maintain muscles even when consuming low calories. To improve cardio endurance, users combine Ostarine with Cardarine.
Basing on the fact that Ostarine can hinder muscle loss for less active individuals or cancer patients, it is only right to conclude that healthy people can also maintain their muscles while on calories free diet with the help of this drug.
(3) Body Recomposition Benefit
individuals who use ostarine for body recomposition experience muscle gain, fat loss and some weight gain that was reliant on the number of calories consumed. Bodybuilders are indifferent regarding body recomposition. Some think it is a good idea while others prefer either cutting or bulking.
Body recomposition is done to boost muscle mass while burning fats. During this phase, the number of calories consumed equals the number of calories expended. One-third of the calories consumed should be derived from lean proteins.
(4) Treating Injuries
Use MK-2866 to heal injuries caused by wrong training methods, recover routine or excessive training. However, if bodybuilders are careful with joint structure and strengthen tendons and ligaments, it is possible to train hard over a long period while avoiding injuries. Additionally, Ostarine treats osteoporosis thanks to its capacity to build up bone density. According to research, MK-2866 beats testosterone at preventing injuries with a dosage of 12.5mg daily.
(5) Vascularity Benefit
Users’ veins bulge out during cycles, and the process continues throughout the phase. The peak is reached in the ninth week then remains consistent during the PCT period.
(6) Clinical Benefits
- Healthy Bones
As people age, bone protecting sex hormone decreases in the body causing Osteoporosis and poor bone health. To prevent this, bone mineralization should follow increased muscle mass to reduce the chances of bone fractures while speeding recovery. The skeletal system is supported by muscles thus the stronger and healthier the muscles the better; chances of fractures are minimized.
- Prevent strength and muscle mass loss
MK- 2866 is still undergoing tests to verify its ability to prevent muscle loss in individuals with muscular dystrophy, an aging population, and cancer patients.
During clinical research, a sample population of 120 healthy aged individuals was given ostarine. Those who were given 3mg ostarine dosage every day for twelve weeks registered increased muscle mass and body fitness. Those who received lower doses did not register any results. Side effects brought about by steroid use were not registered.
In a different test, 159 cancer patients registered an increase in muscle mass. They gained approximately 2-3lbs each within four months. A lower and higher dosage of 1mg daily and 3mg daily respectively worked well in equal measures. More advanced tests on cancer patients to prevent muscle loss and discover other MK-2866 benefits are still underway.
- Boosts heart health
People who have heart disease lose weight and muscle mass. Ostarine comes in handy in such incidences. One hundred and twenty healthy aged individuals administered 1-3mg /day of ostarine in a clinical trial. The dosage reduced blood fats, example, triglycerides, HDL cholesterol, and total cholesterol. Healthy and low lipid levels in the body aid in preventing heart disease. Low level of HDL, though, is not beneficial.
- Insulin Resistance
Ostarine MK-2866 lowers blood glucose and improves insulin resistance just like anti-diabetic drugs. For this reason, ostarine would favor individuals with metabolic syndrome or diabetes when further research is carried out.
MK-2866(Ostarine) is selective on the body organ it targets thus does not bring about the troubles caused by other steroids. Though it does not cause drastic changes over a short period, its results are better in the long run. Other anabolic steroids cause serious side effects such as;
- Suppression or shutdown of pituitary glands.
- Prostate increases in size
- Excessive water retention
- Liver toxicity
- Heart problems
- Reproduction and sexual dysfunction
(1) MK-2866 cycle
With the help of ostarine (841205-47-8), you can enhance muscle mass and maintain strength when on a diet plan. For better results, add a different SARM into the dosage to boost fat loss and muscle mass. A combination of Cardarine and ostarine during cutting improves cardiovascular endurance for an extended period. Most bodybuilders are not aware that cardio has a significant role during cutting phases. A dose of 25mg and 20mg daily of MK-2866 and GW-501516 will give the best results over the cutting period.
(2) MK-2866(Ostrine) Dosage
Since ostarine is still under clinical trial, official dosage plans are minimal thus users have come up with unofficial dosage schedules
- Bulking doses
This phase takes approximately three to eight weeks. Male bodybuilders administer 25mg daily while women use 10mg daily. However, some men use up to 37mg per day which is ten times more than the dose recommended for cancer patients. Men who are 200lbs use even higher doses, which is not recommended.MK-2866 (841205-47-8) has 24 hours half-life thus most people prefer to take the dosage once every day. Others may split the dose into two or three chunks depending on individual preferences.
- Cutting ostarine dosage
The cutting phase takes approximately four to eight weeks. Men use 15 mg to 20mg of ostarine daily. It is not clear the female dosage used, but it is probably half of what male administer.
- Body recomposition doses
A dose of 12.5 mg to 25mg daily is enough for this process.
Some users prefer an ostarine alone dosage while others lower its dosage and combine it with other best SARMs.
MK-2866 cycle takes up to 12 weeks. Some bodybuilders stop at eight weeks and experience less to none side effects compared to those who stop at 12 weeks. Although some users claim that they do not experience any side effects even on longer cycles, it is thought that chances increase with time.
Time off a cycle should always be equal to the cycle duration. For instance, if an individual cycled ostarine SARM for eight weeks, he should take eight weeks break after the cycle. The break should, however, come after administering PCT for 3 to 4 weeks.
Some users do not find it necessary to follow the time- off rule. Lab test should be carried out to determine the hormone levels in the body or any adverse effect after the cycle and PCT. If there is no harm caused, individuals can resume the cycles even after one week break. In case the lab tests show any significant health problem, taking an ostarine or any other steroid break is mandatory.
(1) How to Use On Steroid Cycle Stack
Unlike other anabolic steroids, that strain and cause injury to soft tissues, Mk- 2866( ostarine) are one of the best SARM due to its ability to fasten tissues healing and recovery. For this reason, using an ostarine stack is a sure way of maintaining joint health. 25mgs per day is enough for those engaging in a vigorous workout.
(2) How to Use on a SARMs Stack
A blend of ostarine and any other selective androgen receptor (SARM) is common among steroid users. For fat loss, users can combine 20mgs of Cardarine GW501516 with 25mgms of MK-2866(Ostrine). For joint healing, a stack of 10mgs daily of Ligandrol LGD4033 with 25-50mgs daily of Osterine would work wonders.
(3) How to Use During Post Cycle
Contrary to other steroids, ostarine MK -2866 is not suppressive when administered at a stable dosage for approximately four weeks or so. Users can include 25mgs or less of ostarine in a post cycle therapy. It assists with, muscle wasting, joint health and maintaining strength.
(4) How to Use As a Stand-Alone
Some users prefer to use Ostarine SARM alone with the aim of gaining clean muscle mass or protecting and strengthening their soft tissues. They use 25-50mgs ostarine dosage daily.
(5) Ostarine Dose for Female
Women use MK-2866 since it gives the best results without having to deal with any unpleasant side effects. A dosage of 12.5-25mgs on a daily basis will yield satisfactory results. Other female users may also prefer to combine Ostarine with Cardarine or Stenabolic to invigorate fat loss.
World Anti -Doping Agency prohibited use of SARMs since they raise stamina and improve physical fitness. Clinical tests on ostarine gave positive results, and no significant risk was noted when used together with other common drugs such as statins, antibiotics, Celebrex and antifungals. The only side effect reported under this test was back pain and headache.
To be precise, very little scientific information is available on MK-2866 side effects. However, bodybuilders ostarine reviews and the structure of osterine can be used to clarify the possible side effects of the drug.
Unlike other steroids that increase estrogen levels in the body, Ostarine is not converted to steroid hormone. For this reason, it does not cause serious side effects such as enlarged man breast and gynecomastia. Also, Ostarine MK-2866 does not affect the prostate, sexual and vital organs.
Users have reported that ostarine raises blood estradiol to some extent. Although, this should not be the case since ostarine should not cause a significant hormonal imbalance. According to research, the increase is minimal. Contrary to other steroids Ostarine SARM does not affect the production of testosterone or cause water retention. When on high ostarine dosage, the levels of testosterone production may slightly reduce.
Users reported the following MK-2866 side effects;
- Pain on the testicles
- Minimal to zero muscle size increase at the first five weeks of the cycle.
- Reduced levels of testosterone after a cycle for users who did not do PCT
- Sleep disruptions
- Join pain
- Nausea and headache
- Difficulties erecting
- Irregular menstrual cycles
- High levels of estrogen when on a highostarine dosage
- Depression and a reduced sense of wellness
To combat the effect of low testosterone levels and high levels of estrogens in the system, users embark in post cycle therapy immediately they are done with ostarine cycle. Anti-estrogens such as Nolvadex and Clomid are administered during the 3 to 4 weeks therapy period.
Individuals who take a high ostarine dosage or are highly sensitive to estrogen include an aromatase inhibitor in their stalk to hinder androgen conversion to estrogen. Examples of aromatase inhibitors are Anastrozole and Arimidex. Users who are on low doses do not find it necessary to take aromatase inhibitor or anti-estrogens. Those who undergo a lab test and realize the levels of estrogens are high include an inhibitor in their MK-2866 cycle. To boost testosterone levels, users recommend inclusion of D-Aspartic Acid when on an aromatase inhibitor and post cycle therapy.
A few users pointed out increased hunger when on ostarine bodybuilding. Women, on the other hand, reported unstable menstrual cycles but became stable shortly after they were off the drug.
To sum it up, MK-2866 side effects are minimal as compared to the side effects felt after using other steroids. Users agree ostarine is currently the best SARM available.
James, a male bodybuilder who is in his mid-40, tried out an ostarine (841205-47-8) stalk. His shoulder was severely injured and was in the recovery process. He was using 25mg ostarine MK-2866 dosage plus 25mg MK-677 dosage on a daily basis for 12 consecutive weeks.
He gave the following reports;
- He was able to work out again without any shoulder pains. This was a vast improvement after a severe injury.
- He shed 4% of his body fat and added 15lbs lean muscle. Osterone bodybuilding was evident. He was amazed that MK-2866 works better than other steroids he had used before.
The MK 2866 benefit amused James to the extent that he wanted to go on with the dosage for a more extended period. However, to avoid stubborn side effects, he was advised to take a break off the drug and take up a PCT. Most individuals lack the knowledge on how to take ostarine dosage. The results could not have been good for James if he was not well informed.
In the recent past, the government has restricted the sale of ostarine. However, it is readily available in the black market. Most companies sell bogus ostarine or mix a small amount of the drug with some herbs or prohormones. Not every post stating MK-2866 for sale online should be trusted. Only a few authentic sellers are available in the market.
Buy MK-2866 (841205-47-8) from us and enjoy ostarine bodybuilding effects at affordable prize.
- Evans, W., Smith, M. R., Morley, J. E., Barnette, K. G., Rodriguez, D., Steiner, M. S., & Dalton, J. T. (2007). Ostarine increases lean body mass and improves physical performance in healthy elderly subjects: implications for cancer cachexia patients. Journal of Clinical Oncology, 25(18_suppl), 9119-9119.
- Schragl, K. M., Forsdahl, G., Gmeiner, G., Enev, V. S., & Gaertner, P. (2013). Novel pathway for the synthesis of arylpropionamide-derived selective androgen receptor modulator (SARM) metabolites of andarine and ostarine. Tetrahedron Letters, 54(18), 2239-2242.
- Zilbermint, M. F., & Dobs, A. S. (2009). Nonsteroidal selective androgen receptor modulator Ostarine™ in cancer cachexia. Future Oncology, 5(8), 1211-1220.