Erectile dysfunction (ED) has become a common health issue amongst men, especially those who’ve hit 40. A recent research shows that 5% of men aged 40 years suffer from complete dysfunction. The percentage increases to 15 for 70 years-old men. To address this problem, scientists have come up with various medications aimed at helping men maintain their masculinity with proper erection capability. Tadalafil (CAS 171596-29-5) is one of the most prominent ED treatment medications.
♦ Brand name: Cialis, Adcirca, etc.
♦ Chemical structure of Tadalafil
Tadalafil is a FIDA-approved oral drug used for the treatment of dysfunction or impotence among men. It functions similarly to similar to Viagra and Levitra by increasing the flow of blood to the penis and as a result, enables a man to get an erection. It is suitable for adult men who have difficulties in attaining or maintaining a penile erection.
♦ Tadalafil history
Galxo Wellcome, in collaboration with Lilly ICOS, a biotechnology company, was the first to discover and develop Tadalafil. However, the companies parted ways in 1996 and two years later, ICOS Corporation and Eli Lilly entered a joint venture and formed a new company called Lilly ICOS, LLC. The venture developed the drug again and started to sell it as Cialis.
After a few years, Lilly ICOS, LLC. filed a new application for the drug with Tadalafil as the generic name and Cialis as the brand name. December 2003 was a historic moment for Tadalafil as it is the time that it was approved by the Food and Drug Administration (FDA) for sale in the United States as a drug for dysfunction treatment.
Tadalafil (171596-29-5) — How does it work?
Men with ED usually have an enzyme called PDE5. This enzyme suppresses cyclic guanosine monophosphate (cGMP), an extremely important substance in the processing of a healthy penile erection. cGMP helps a man’s nerve ending signals in the pelvic region to trigger nitric oxide release. As a result, the smooth linings of his pelvic blood vessels relax and this leads to increased blood flow through the vessels to fill the cavernous structures of his penile body. This makes the penis to become hard and engorged.
Higher amounts of PDE5 and insufficient cGMP in a man make his body unable to decipher the signals released by his nerve endings, leading to partial or complete loss of ability to get a penile erection. Men with erection problems have low blood flow to their penises. Since a penis becomes hard as a result of increased supply, such men cannot get an erection due to lack of insufficient blood in their penises. Semaglutide Effects Only as Peptide? NO, Much More Than That!
When a man with penile erection incapability takes Tadalafil (171596-29-5) as prescribed, the drug reduces the effects of PDE5 in his body system and this makes cGMP concentration to return usual level. Just like other Erectile dysfunction drugs, Tadalafil works by widening a man’s blood vessels and as a result, when sexually stimulated, the blood flow to his penis increases, the organ becomes hard, hence an erection.
Although the medication acts similarly to Viagra, Spedra and Levitra its effect lasts longer- up to 36 hours. No wonder it is called a weekend pill, simply because a single dose of the drug can make a man with ED have a normal erection and enjoy sexual intercourse with his partner for nearly a whole weekend.
When a man takes a 36-hour Tadalafil dose, the drug reduces the PDE5 level in his body quickly (in about 15 to 45 minutes) and as a result, cGMP returns to normal levels. Nevertheless, since the medication has a relatively short half-life, its effect disappears within two days and as a result, the level of PDE5 increases again and the man loses his penile erection capability again.
On the other hand, when a man is taking daily Tadalafil dose for ED treatment, the drug helps in keeping cGMP in his body in healthy levels all the time as long as he adheres to the drug’s prescription religiously. This helps the man to get an erection easily whenever he’s sexually stimulated. However, the daily dose of low-strength Tadalafil usually takes 4 to 5 days to begin working. So, don’t be in a hurry to become a bed tiger upon taking the first pill; just let the period lapse and you’ll be just that as long as you take it as prescribed.
Being a prescription-only medication, a man ought to be extra cautious while planning to take it. Particularly, he ought to do and observe various things before, when and after taking it.
Let’s start with the things that one should do before taking the drug.
Do the following before taking Tadalafil:
♦ Visit a doctor or pharmacist for advice on the right Tadalafil dosage for you, among other prescription information.
♦ In case you are allergic to certain medications, including Tadalafil itself or some of its ingredients, let the doctor or pharmacist know about it. You can get information about the ingredients of the drug from the medical expert.
♦ Let your doctor know in case you have taken riociguat or nitrates isosorbide dinitrate and nitroglycerin in the recent past or still on them. You can confirm from the doctor or pharmacist if the drugs you are using (if any) have nitrated. You might be advised not to take Tadalafil if the doctor finds out that you are taking nitrates because they don’t get along well with Tadalafil.
♦ Remember that Tadalafil comes with a brand name Adcirca or Cialis. Therefore, you should not take both concurrently, otherwise, you’ll have abused the drug and the outcome might be undesirable. You should only be treated with any of them at a time.
♦ Are you taking (or planning to take) any other medication, be it prescription or nonprescription, vitamins or nutritional supplements? If yes, bring it to the attention of the medical expert. Such information is crucial as it’ll help the doctor or pharmacist to establish the dosage that will be best for you, considering the other medication or supplements that you are using or intend to use. Upon having the information, the specialist may find it necessary to monitor you closely for possible side effects.
♦ Are you using any herbal product, particularly St. John’s wort? If yes, let the specialist know about it.
♦ In case you are a smoker and at one or several occasions have ever had an erection that persisted for over four hours, you need to tell your doctor or pharmacist about it.
♦ Tell your doctor if you have vomited, sweated abnormally, had diarrhea, or not been taking sufficient water and so you suspect that you might be insufficiently hydrated.
♦ Let your doctor know if you have ever suffered from the pulmonary veno-occlusive disease in your life or any other health condition that’s likely to affect the shape of your penis. Such conditions include diabetes, high or low blood pressure, heart attack/failure, blood circulation issues, blood cell issues, irregular heartbeat, chest pain, multiple myeloma, stomach ulcers, bleeding disorders, a heart disease, a kidney disease, a liver disease and stroke
♦ If you love alcoholic beverages and you’d like to use them while taking Tadalafil, you need to discuss with your doctor about it. Upon an assessment of your health, your doctor will advise you accordingly, whether to avoid the drinks or take them moderately. In the case of wine or whiskey, you might be advised to take not more than five glasses. This is because high alcohol intake while one is on the effects of Tadalafil can cause side effects like low blood pressure, increased heartbeat rate, headache as well as dizziness.
♦ In case you had previously been advised by a health specialist to refrain from having sexual intercourse due to a medical reason, you should bring it to the attention of your doctor.
♦ Tell your doctor if you have ever had chest pain while performing a sexual activity. Your heart may be strained as a result of your engagement in a sexual activity, particularly if you are suffering from a heart illness.
♦ Tell your doctor if you’re prostrate or part of it has been removed.
You should not take Tadalafil in case:
♦ You have ever had a vision-impairing condition called Non-arteritic anterior ischemic optic neuropathy (NAION)
♦ You suffer from a heart illness
♦ You have suffered from stroke or a heart attack, recently, particularly in the last six months
♦ You are suffering from low blood pressure
♦ Having uncontrollable hypertension
♦ Allergic to the ingredients of Tadalafil
♦ Bear in mind that the effect of the drug might not be instant. Although 36-hour dose gives the desired Tadalafil results faster as compared to a daily dose, you are likely to wait for about 15 to 45 minutes to feel the desired effect of the drug.
♦ Don’t take nitrates for at least 48 hours before the time you are expecting to take Tadalafil.
♦ Get Tadalafil from a trusted source. You can count on Phcoker.com for genuine Cialis products, including Tadalafil.
♦ Once your doctor has found that you are fit to use Tadalafil and prescribes you the right dose for the treatment of ED, there are various things that you ought to do while taking the medications. Here is a list of the dos and the don’ts:
♦ Ensure that you adhere fully to the dosage instruction given by your doctor. Take the medication precisely the way the specialist advised you. You are supposed to take the drug at least half an hour prior to the time you have planned to engage in sexual intercourse.
♦ Swallow the tablet whole with a drink of water. You can take it with or without food. Do not drink an excessive amount of alcohol while taking the medication, as this increases your risk of side effects such as dizziness when you stand up.
♦ Avoid drinking grapefruit juice, eating grapefruit or using grapefruit products while you are taking Tadalafil since grapefruit content can interfere with the effectiveness of the medication.
♦ You should also avoid taking alcohol while using the ED medication. The reaction of the drug and alcohol can make you experience some side effects.
♦ You should take the drug strictly as per the amount recommended by the doctor; not more, not less.
♦ Don’t take the medication for a longer period than prescribed.
♦ You can take Tadalafil with or without food
♦ Swallow the Tadalafil tablet whole with a mouthful of water; do not break or split the tablet.
♦ You should take Tadalafil before having sex and not more than one time in a day.
♦ You must necessarily be on a dosage schedule of the medication. Therefore, just take it as prescribed by the medical expert.
♦ In case you’ve missed a dose, don’t take extra Tadalafil to make up. If you missed, just let it go just like that and continue taking as prescribed.
After taking Tadalafil
♦ Make sure you are sexually stimulated if you want to erect and enjoy sex because the drug will only be effective if you are stimulated sexually.
In case you have recently taken Tadalafil or still on its course and you need emergency heart problem medical treatment, let your health care provider know about it as well. Tadalafil reacts to heart medications and so, upon revealing such information to your health specialist, they’ll be able to establish the safest course of action, considering the possible effectiveness of Tadalafil in your body. Therefore, your doctor will be interested in knowing when you last took the medication.
♦ Make sure that you keep the medication at a room temperature, in a cool and dry place; away from heat and moisture.
Although Tadalafil is very effective as an ED treatment, it can cause some undesired effects. Although a man who has taken the medication is not likely to experience all these side effects, he should seek medical attention in case he experiences some of them.
▲ The side effects that must require doctor’s attention
king the medication since some of them can be fatal if they are unaddressed on time.
A: The Common side effects
In this case, the common side effects include:
- Arm pain
- Jaw pain
- Back pain
- Neck pain
- Leg pain
- Upset stomach
- Stuffy nose/ nasal congestion
- Unclear sight
- Chest pain
- Chest discomfort
- Tight chest
- Heavy chest
- Irregular heartbeat
- Slow heartbeat
- Fast heartbeat
- Cold sweats
- Loss of hearing capability
- Faintness or lightheadedness while getting up quickly from a lying/sitting position
- Passing out
- Abnormal exhaustion or weakness
- Warmth, redness, or tingly sensation
- Swollen lips, tongue or throat
- Ringing in your ears
B: Rare side effects
(1) With a severe expression
Although the following Tadalafil side effects are rare, they mostly have a severe expression if they occur.
- Painful or prolonged penis erection
- Unusual liver function tests
- Blocked or closed eye retina blood vessels
- Anal blood discharge
- Reduced blood pressure when you stand
- Swallowing difficulties
- Unusually low blood pressure
- Eye disease as a result of blood flow issues
- Heart attack
- Heart throbbing or pounding
- Inflamed esophagus
- Kidney disease and reduced kidney function
- Sudden loss of vision
- Pink eye
- Swollen face
- Skin rash and skin sloughing
- Stevens – Johnson syndrome
- Breathing difficulties
(2) Less Severe expression
The following are also rare side effects of Tadalafil (171596-29-5) but they have a less severe expression as compared to the previously listed.
- Fluid accumulation in the eyelid tissues
- A burning sensation in the stomach
- Chronic sleep issues
- Acquired abnormally colored sight
- Abnormal mouth dryness
- Short-term memory loss episodes
- Too much sweating
- Excessive watery eyes
- Fluid accumulation in the legs, hands, feet or arms
- Too much blood in the eye lining
- Painful joints
- Loose stools
- Regular erections
- Painful eyes
- A spinning or whirling feeling
The above list doesn’t comprise all the side effects of the drugs. Therefore, you are advised to get comprehensive information about all the possible effects from your doctor. In case you experience another side effect that is not listed here, you can report it to FDA at 1-800-FDA-1088.
▲ The side effects that don’t require doctor’s attention
A Tadalafil side effect must not require medical attention to go away. Some go away by themselves once your body gets used to the medication. Besides, your health care provider may advise you on how to prevent or minimize such effects. However, you can still check with your health specialist if they are persistent or bothering you much. Some of these side effects are more common than others. Let’s start with the more common:
A: More-common self-healing side effects
- Acid or sour stomach
- Stomach discomfort
- Stomach upset
B: Less-common self-healing side effects
These Tadalafil side effects go away on their own without any medical intervention but they are less-common.
- Bloody nose
- Prickling, “pins and needles”, tingling, crawling and burning sensations
- Painful, burning or dry eyes
- Nasal congestion
- Dry or a sore throat
- Excessive tiredness
- Loose stools
- Muscle cramps and aches
- Stiff muscles
- Neck, arm and/or leg pain
- Painful or burning throat
- Painful, swollen or reddened eyes, eyelid or eyelid’s inner lining
- Reduced sensitivity to touch
- Spinning sensation
- Dizziness or unusual drowsiness
- Lack of sleep
- Impulsive erection of the penis
- Stomach upset
- Puffy or swollen face
- Swelling of joints
- Upper abdominal or stomach pain
- Hoarse voice
- Watery eyes
Tadalafil comes in the form of tablets, liquid or. Whichever form in which you take the medication, rest assured that it is as effective as the medication in any of the two other forms. Liquid Tadalafil is similarly effective as or tablet Tadalafil as long as you’ve bought the medication from a trusted source. Although there might be a difference, it should be fairly insignificant.
♦ Tadalafil pills or tablets
As earlier mentioned Tadalafil comes as tablets, pills liquid or. Tadalafil tablets or pills are yellow in colour, coated with a film and are almond-shaped. They are sold in 2.5, 5mg, 10mg and 20mg doses. The 9 questions to ask yourself before taking Avanafil
The tablets come in packets of 5, 10, 15, 30 and 90 tablets each. You can also get the medication as a 4, 8, 12, 16 or 28 tablet packet.
Tadalafil tablets for daily use comes in 2.5 mg and 5 mg doses while the 10mg dose is used only when a man is about to have sex; at least 30 minutes before engaging in a sexual intercourse. Considering the effectiveness of the drug in a man and his tolerability to the medication, the doctor may prescribe the on as-needed dosage to be increased to 20 mg or reduced to 5 mg. The 5mg when-needed dose is suitable for men with less-severe ED.
The recommended daily Tadalafil dose is usually 2.5 mg and ought to be taken as at a specific time every day. However, depending on the efficacy and tolerability, the dosage may be increased to 5 mg.
▲ Are there Tadalafil counterfeit tablets or pills?
Among the various forms of Tadalafil, the medication in tablet or pill form is the most likely to be the tablets have been around for the longest time as compared to Tadalafil, suspensions and gels. The makers of counterfeits know that the drug’s tablets are the most popular and so, they take advantage of that to supply their fabricated tablet drugs. Therefore, you need to be extra cautious while buying Tadalafil, especially the tablets. Preferably, get them from a reputable source, particularly from Phcoker.com, among other trusted Cialis suppliers and manufacturers. However, that doesn’t mean that you should not have a keen eye while buying Tadalafil suspensions and gels.
Liquid Tadalafil is milky white in color and just like tablets, should be stored in cool and dry place, away from heat, moisture as well as direct exposure to light. Men who experience difficulty swallowing tablets find Tadalafil easier to use while it is liquid form. Besides, people who are vulnerable to digestive conditions such as dyspepsia prefer liquid Tadalafil because it is easily digestible and absorbable by the body. Besides, the medication in liquid form starts working earlier as compared to tablets.
Essentially, it doesn’t matter if you have used liquid Tadalafil or Tadalafil tablets or, as long as you’ve bought it from a trusted source, you should rest assured of that good erection you need to feel more masculine. Therefore, you must not spend much of your time looking for a particular form of the pill (unless you have a swallowing or digestive issue). If you get the tablets, liquid or, you are good to go.
At the end of the day, it doesn’t matter if you are using liquid Tadalafil or Cialis pills; you are still more than just likely to achieve that good erection you need. So don’t spend too much time looking for the better option of the two – they both are good enough to make you and your partner smile.
The liquid formulations of Tadalafil were released to the market after the tablets. So, they are less popular as compared to tablets and so, some people might question their effectiveness but the fact is they are equally effective. All formulations of the medication use exactly the same active ingredient and so, they are equally reliable. Nevertheless, ensure that you get liquid Tadalafil from a trusted seller for certainty that you are using genuine and safe medication.
▲ How to use liquid Tadalafil
Liquid Tadalafil comes in air-tight and easy to open bottles.
You are supposed to shake the bottle first before use to ensure that the solution is homogeneously concentrated.
You can use an eyedropper to draw the right dosage of the medication
Put the medication on your tongue and swallow. The drug is tasteless and so, friendly to people who don’t like tasting medications as well as their unpleasant after back tastes.
A 5ml dose of Tadalafil is enough to help you get an almost-instant reaction. Nevertheless, remember we said you should take the drug according to your doctor’s instructions.
If you take the drug on an empty stomach, you are likely to get an erection within 15 to 20 minutes of taking it. However, you are going to have the best results of the medication after about an hour.
Therefore, don’t rush to take another dosage if you don’t see results within 15 to 20 minutes. Just relax and wait for 60 to 90 minutes to see if you’ll have felt the desired effect of the drug.
If the results are not forthcoming despite waiting for 60 to 90 minutes, consult your healthcare specialist for guidance on what to do next. Most likely, you’ll be advised to take an additional 1ml dosage of the medication.
The major differences between liquid Tadalafil and Tadalafil tablets are that the former is more easily absorbed through the walls the digestive tract and so, it is to a certain extent softer and gentle on the digestive system. When it comes to the tablets, they must be broken down to a form in which they can be absorbed by the digestive tract before absorption and so, their effect takes longer to manifest.
That’s why people who are susceptible to digestive issues like dyspepsia and gastroesophageal reflux prefer liquid Tadalafil to tablets. The issues are less common when one takes the liquid formulation and compared to when one has taken the drug in tablet form.
Tadalafil is the raw material of Tadalafil. The drug is white in colour and is mostly used in the manufacturing of Tadalafil tablets. You can get genuine Tadalafil from a high-purity supplier such as Phcoker.com.
Other than making Tadalafil tablets and pills, Tadalafil can also be used to make sexual candy and sex coffee.
♦ Tadalafil for Sexual candy
Sexual sweets are very prominent among men with sexual issues, especially those with low sexual drive and those penile erection difficulties as these candies improve their sexual desire and capabilities. Tadalafil is a common ingredient in such candies. The candies are sweet and so, encourages one to take the sex enhancement ingredient hassle-free.
♦ Tadalafil for Sex coffee
Ever heard of sex coffee? Well, these are kinds of drinks containing ingredients that can increase your libido. A certain amount of Cialis can be used to make sex coffee, depending on the desired strength of the desired sex enhancement effect.
Other than Tadalafil, sex coffee contains other ingredients like coconut milk, maca, cinnamon, honey and Cacao. Therefore, the drink has a slightly spicy flavor while its sweetness appeals your taste buds. In as such, you won’t even feel like you are taking a drug.
The amount of Tadalafil in sex coffee is influenced by the desired strength of the effect of the medication in a man’s body upon taking the drink.
♦ Other forms
Tadalafil also comes as a jelly. Tadalafil jelly is an oral ED medication and you should allow is to dissolve in your mouth before swallowing it. It is easy to swallow and so, suitable for people experiencing swallowing difficulties as well as the elderly.
The majority of men who have used Tadalafil are thrilled by its results. Let’s sample some of the feedback we’ve received from our clients about the drug.
Thomson from Europe: “He says that he has been using Tadalafil for the last five months and he’s happy to have found it. “I am 64 years old and happy because, despite my over 15 years of struggling to enjoy sex with my girlfriends, I can now feel more man since the time I discovered this drug. I get an erection like I used to do in my early 20s,” he says. He goes on to advise other men with erection issues to try Tadalafil and he’s certain that they too will find it helpful.”
Cheng from China: “He says that his newly-wed wife almost left him while on their honeymoon since he could not satisfy her in bed. He shared the experienced with a friend who advised him to use Tadalafil. “After taking Tadalafil, we had the best moments of our honeymoon and the perception that my wife had towards me changed. However, I’m yet to disclose to her that I use sex enhancement drugs but I’ll let her know with time. I can’t thank enough whoever came up with this medication,” he says.”
Lam from China: “He says that of all the sex enhancement drugs he has ever used, Tadalafil is the best. “Its results are instant and last for the longest time as compared to other brands,” he writes.”
Khatri from India: “Tadalafil is ultra-effective and worth every coin in its price,” he comments. He adds that although initially, he used to have a fever and facial inflammation after using it, nowadays he doesn’t experience any side effect upon taking the medication.”
Tong from China: “I’m both a consumer and a seller of Tadalafil and from the experience, I have had with the drug, I can confidently say that it works,” Tong says. “I highly recommend it to any adult male with dysfunction, “he adds.”
Zoeng from China: “Tadalafil has helped me big time to regain my self-esteem as a man. I use it occasionally, especially on weekends when I’m expecting to lay someone and I have never disappointed me. I would only wish I could get it from my local pharmacy. Hopeful that the suppliers will do the necessary.”
George: “He says that he and his buddy use Tadalafil and they both like it. He highly recommends it to other men with penile erection issues.”
Isaac: “Isaac says that he uses Tadalafil and is amazed by its results. “ I wish I knew about it earlier,” he continues to say.”
Tadalafil– How to buy Tadalafil online?
You don’t have to move up and down looking for a place from which you can buy Tadalafil. You can simply buy the medication from Phcoker.com at the comfort of your PC or smartphone.
Here are the steps of the online purchase:
♦ Go to Phcoker.com website
♦ Search “Tadalafil”
♦ Fill and submit the application form for the purchase
♦ You might be asked to fill in a short medical questionnaire; fill it in and submit. Our specialist will review and possibly approve your order.
♦ Once your order is approved, you’ll pay for the product and then wait for Phcoker.com to deliver it to you.
（1）Tadalafil price in the market
Tadalafil is sold at different prices by different sellers. Here is a sample price range of Tadalafil Canada as at the time of writing this article (November 2018).
|Number of tablets per packet||Weight per tablet||Market Price range|
|6||2. 5 mg||$27-$109|
|7||2. 5 mg||$31-$108|
|8||2. 5 mg||$35-$108|
|30||2. 5 mg||$116-$268|
|90||2. 5 mg||$338-$784|
Hopefully, the table gives you a glimpse of Tadalafil cost.
（2）Tadalafil supplier/manufacturer from different countries
Xuchang Shangke Chemical Co., Ltd, also known as Phcoker, is a China-based high-tech enterprise that specializes in the manufacturing of active pharmaceutical intermediates and products which include Tadalafil. The company deploys top-creams in the pharmaceutical industry as well as state-of-the-art equipment besides using top-class laboratories for accurate production quality control. Phcoker.com is a go-to shop for customers from China, North America, Europe and India who need genuine Tadalafil. It is where you can get Tadalafil best price.
There are other companies that supply Tadalafil to various parts of the globe. Here is a table indicating the other active manufacturers and suppliers and the countries in which they are based:
Men, especially those who’ve hit 60 years are susceptible to ED. Luckily, following the release of Tadalafil; every man now can enjoy having good sex irrespective of his age, thanks to the effect of the medication. Nevertheless, you should seek advice from a healthcare specialist if you want to use this medication to avoid some possible side effects.
Even having adhered to doctor’s advice, a man who has used Tadalafil can experience one or several side effects, some of which require professional medical attention while others can just disappear on their own with time. The most popular nootropic Fasoracetam: what does it give us?
Tadalafil comes as tablets, pills, liquid,, candies and coffee as well as in a jelly form. Tadalafil tablets, pills and liquid are equally effective since they have the same active ingredients. When it comes to coffee and candies, the effectiveness of the drug is dependent on the quantity of the medication used as an ingredient in the products.
If you want to be sure that the Tadalafil that you are using is genuine, purchase it from a trusted Tadalafil supplier or Tadalafil manufacturer like Phcoker.com. Tadalafil is your go-to drug for you ED treatment need as a man.
1.National Centre For Biotechnology Information, US. National Library Of Medicine, Tadalafil, Pubchem Sections 1-10.
2.Evelyn C. Cortez, CIALIS (Tadalafil): Uses, Dosage, Side Effects Information and Where to Buy Generic Cialis (Tadalafil), Viagra (Sildenafil), and Other Best Drugs Cheap and Safely Online, Published, 13 Dec 2017, page 5-3
3.James Lee Anderson, Cialis, Tadalafil: Treats Erectile Dysfunction, Symptoms of Benign Prostatic Hyperplasia, and Pulmonary Arterial Hypertension, CreateSpace Independent Publishing Platform, 26 Mar 2015, page 5-47.
Hot topic discussion：
|1.||Is Tadalafil Safe?||2.||How can I improve my dysfunction?|
|3.||an I drink with Cialis?||4.||How to improve tadalafil effects?|
|5.||What is the best pill for dysfunction?||6.||How long can you take tadalafil for?|